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Ribonuclease κ promotes longevity by preventing age-associated accumulation of circular RNA in stress granules.

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Title: Ribonuclease κ promotes longevity by preventing age-associated accumulation of circular RNA in stress granules.
Authors: Kim SS; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Ham S; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Boo SH; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Lee D; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Min H; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Kang E; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Haque R; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Lee H; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Jung Y; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Kwon S; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Park S; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Park HH; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Kim EJE; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Hwang W; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 37673, South Korea., Kim E; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Lee GY; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Park KY; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea., Suh JM; Graduate School of Medical Science and Engineering, KAIST 34141, Daejeon, South Korea., Lee G; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea. Electronic address: ifglee@kaist.ac.kr., Kim YK; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea. Electronic address: yk-kim@kaist.ac.kr., Lee SV; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea. Electronic address: seungjaevlee@kaist.ac.kr.
Source: Molecular cell [Mol Cell] 2026 Mar 05; Vol. 86 (5), pp. 885-900.e14. Date of Electronic Publication: 2026 Feb 24.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE
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  Data: Ribonuclease κ promotes longevity by preventing age-associated accumulation of circular RNA in stress granules.
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  Data: <searchLink fieldCode="AU" term="%22Kim+SS%22">Kim SS</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Ham+S%22">Ham S</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Boo+SH%22">Boo SH</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Lee+D%22">Lee D</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Min+H%22">Min H</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Kang+E%22">Kang E</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Haque+R%22">Haque R</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Lee+H%22">Lee H</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Jung+Y%22">Jung Y</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Kwon+S%22">Kwon S</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Park+S%22">Park S</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Park+HH%22">Park HH</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Kim+EJE%22">Kim EJE</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Hwang+W%22">Hwang W</searchLink>; Department of Life Sciences, Pohang University of Science and Technology, Pohang, Gyeongbuk 37673, South Korea.<br /><searchLink fieldCode="AU" term="%22Kim+E%22">Kim E</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Lee+GY%22">Lee GY</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Park+KY%22">Park KY</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Suh+JM%22">Suh JM</searchLink>; Graduate School of Medical Science and Engineering, KAIST 34141, Daejeon, South Korea.<br /><searchLink fieldCode="AU" term="%22Lee+G%22">Lee G</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea. Electronic address: ifglee@kaist.ac.kr.<br /><searchLink fieldCode="AU" term="%22Kim+YK%22">Kim YK</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea. Electronic address: yk-kim@kaist.ac.kr.<br /><searchLink fieldCode="AU" term="%22Lee+SV%22">Lee SV</searchLink>; Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu 34141, Daejeon, South Korea. Electronic address: seungjaevlee@kaist.ac.kr.
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  Data: <searchLink fieldCode="JN" term="%229802571%22">Molecular cell</searchLink> [Mol Cell] 2026 Mar 05; Vol. 86 (5), pp. 885-900.e14. <i>Date of Electronic Publication: </i>2026 Feb 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9802571 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-4164 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210972765%22">10972765 </searchLink><i>NLM ISO Abbreviation: </i>Mol Cell <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.molcel.2026.01.031
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              Text: 2026 Mar 05
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