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Polystyrene microplastic-induced pathophysiology is driven by disruption of efferocytosis.

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Title: Polystyrene microplastic-induced pathophysiology is driven by disruption of efferocytosis.
Authors: Codo AC; Immunology & Microbial Pathogenesis Graduate Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Romero-Pichardo JE; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Wang Z; Immunology & Microbial Pathogenesis Graduate Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Aufiero MA; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lazarov T; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Saitz Rojas W; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Walker NS; Tri-Institutional Program in Chemical Biology, New York, NY, USA; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Nair A; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Cole RF; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; ACCESS Summer Research Program, Weill Cornell Medicine, New York, NY, USA; University of Central Florida, Orlando, FL, USA., Adkins S; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Dong E; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Fadojutimi K; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Bridge Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Martínez de la Torre C; Department of Radiology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., David Y; Tri-Institutional Program in Chemical Biology, New York, NY, USA; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA; Department of Physiology, Biophysics, and System Biology, Weill Cornell Medicine, New York, NY, USA., Hohl TM; Immunology & Microbial Pathogenesis Graduate Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Immuno-Oncology, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Infectious Disease Service, Department of Medicine, Memorial Hospital, New York, NY, USA., Geissmann F; Immunology & Microbial Pathogenesis Graduate Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Keshari KR; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Bridge Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Radiology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Cornell Graduate School of Medical Sciences, New York, NY, USA., Lucas CD; University of Edinburgh Centre for Inflammation Research, Edinburgh BioQuarter, UK; Institute for Regeneration and Repair, Edinburgh BioQuarter, UK., Perry JSA; Immunology & Microbial Pathogenesis Graduate Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: perryj@mskcc.org.
Source: Immunity [Immunity] 2026 Mar 10; Vol. 59 (3), pp. 618-636.e11. Date of Electronic Publication: 2026 Feb 24.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE
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  Data: Polystyrene microplastic-induced pathophysiology is driven by disruption of efferocytosis.
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  Data: <searchLink fieldCode="AU" term="%22Codo+AC%22">Codo AC</searchLink>; Immunology & Microbial Pathogenesis Graduate Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Romero-Pichardo+JE%22">Romero-Pichardo JE</searchLink>; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Immunology & Microbial Pathogenesis Graduate Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Aufiero+MA%22">Aufiero MA</searchLink>; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lazarov+T%22">Lazarov T</searchLink>; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Saitz+Rojas+W%22">Saitz Rojas W</searchLink>; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Walker+NS%22">Walker NS</searchLink>; Tri-Institutional Program in Chemical Biology, New York, NY, USA; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Nair+A%22">Nair A</searchLink>; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cole+RF%22">Cole RF</searchLink>; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; ACCESS Summer Research Program, Weill Cornell Medicine, New York, NY, USA; University of Central Florida, Orlando, FL, USA.<br /><searchLink fieldCode="AU" term="%22Adkins+S%22">Adkins S</searchLink>; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Dong+E%22">Dong E</searchLink>; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Fadojutimi+K%22">Fadojutimi K</searchLink>; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Bridge Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Martínez+de+la+Torre+C%22">Martínez de la Torre C</searchLink>; Department of Radiology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22David+Y%22">David Y</searchLink>; Tri-Institutional Program in Chemical Biology, New York, NY, USA; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Pharmacology, Weill Cornell Medicine, New York, NY, USA; Department of Physiology, Biophysics, and System Biology, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hohl+TM%22">Hohl TM</searchLink>; Immunology & Microbial Pathogenesis Graduate Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Immuno-Oncology, Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Infectious Disease Service, Department of Medicine, Memorial Hospital, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Geissmann+F%22">Geissmann F</searchLink>; Immunology & Microbial Pathogenesis Graduate Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Keshari+KR%22">Keshari KR</searchLink>; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Bridge Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Department of Radiology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Weill Cornell Graduate School of Medical Sciences, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lucas+CD%22">Lucas CD</searchLink>; University of Edinburgh Centre for Inflammation Research, Edinburgh BioQuarter, UK; Institute for Regeneration and Repair, Edinburgh BioQuarter, UK.<br /><searchLink fieldCode="AU" term="%22Perry+JSA%22">Perry JSA</searchLink>; Immunology & Microbial Pathogenesis Graduate Program, Weill Cornell Graduate School of Medical Sciences, New York, NY, USA; Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY, USA. Electronic address: perryj@mskcc.org.
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  Data: <searchLink fieldCode="JN" term="%229432918%22">Immunity</searchLink> [Immunity] 2026 Mar 10; Vol. 59 (3), pp. 618-636.e11. <i>Date of Electronic Publication: </i>2026 Feb 24.
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