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Cerebrospinal Fluid Metagenomic Next-Generation Sequencing in Pediatric Central Nervous System Infection: Clinical Experience and Diagnostic Stewardship Strategies.

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Title: Cerebrospinal Fluid Metagenomic Next-Generation Sequencing in Pediatric Central Nervous System Infection: Clinical Experience and Diagnostic Stewardship Strategies.
Authors: Li G; Division of Pediatric Infectious Diseases, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, USA., Puumala E; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Zhang Z; School of Public Health, University of California, Berkeley, Berkeley, California, USA., Rajapakse NS; Division of Pediatric Infectious Diseases, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, USA., Ristagno EH; Division of Pediatric Infectious Diseases, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, USA., Wolf MJ; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Rodning AA; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Simner PJ; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA., Gaensbauer JT; Division of Pediatric Infectious Diseases, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, USA., Patel R; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.; Division of Public Health, Infectious Diseases and Occupational Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
Source: Open forum infectious diseases [Open Forum Infect Dis] 2026 Feb 05; Vol. 13 (2), pp. ofag054. Date of Electronic Publication: 2026 Feb 05 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Published by Oxford University Press on behalf of the Infectious Diseases Society of America Country of Publication: United States NLM ID: 101637045 Publication Model: eCollection Cited Medium: Print ISSN: 2328-8957 (Print) Linking ISSN: 23288957 NLM ISO Abbreviation: Open Forum Infect Dis Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Cerebrospinal Fluid Metagenomic Next-Generation Sequencing in Pediatric Central Nervous System Infection: Clinical Experience and Diagnostic Stewardship Strategies.
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  Data: <searchLink fieldCode="AU" term="%22Li+G%22">Li G</searchLink>; Division of Pediatric Infectious Diseases, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Puumala+E%22">Puumala E</searchLink>; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Z%22">Zhang Z</searchLink>; School of Public Health, University of California, Berkeley, Berkeley, California, USA.<br /><searchLink fieldCode="AU" term="%22Rajapakse+NS%22">Rajapakse NS</searchLink>; Division of Pediatric Infectious Diseases, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Ristagno+EH%22">Ristagno EH</searchLink>; Division of Pediatric Infectious Diseases, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Wolf+MJ%22">Wolf MJ</searchLink>; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Rodning+AA%22">Rodning AA</searchLink>; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Simner+PJ%22">Simner PJ</searchLink>; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Gaensbauer+JT%22">Gaensbauer JT</searchLink>; Division of Pediatric Infectious Diseases, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, USA.<br /><searchLink fieldCode="AU" term="%22Patel+R%22">Patel R</searchLink>; Division of Clinical Microbiology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.; Division of Public Health, Infectious Diseases and Occupational Medicine, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA.
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  Data: <searchLink fieldCode="JN" term="%22101637045%22">Open forum infectious diseases</searchLink> [Open Forum Infect Dis] 2026 Feb 05; Vol. 13 (2), pp. ofag054. <i>Date of Electronic Publication: </i>2026 Feb 05 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Published+by+Oxford+University+Press+on+behalf+of+the+Infectious+Diseases+Society+of+America%22">Published by Oxford University Press on behalf of the Infectious Diseases Society of America </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101637045 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2328-8957 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223288957%22">23288957 </searchLink><i>NLM ISO Abbreviation: </i>Open Forum Infect Dis <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 Feb 05
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