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Quantitative measures of total and phosphorylated alpha-synuclein in skin tissue as potential biomarkers for synucleinopathies.

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Title: Quantitative measures of total and phosphorylated alpha-synuclein in skin tissue as potential biomarkers for synucleinopathies.
Authors: van der Gaag BL; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands., van Wetering J; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands., Morella ML; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands., Breve JJ; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands., Reijner N; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands., Pfeifer J; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Delft University of Technology, Delft, The Netherlands., Simando A 3rd; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Department of Biology, De La Salle University, Manila, Philippines.; St. Luke's Medical Center College of Medicine - William H. Quasha Memorial, Quezon City, Philippines., van Hilten JJ; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands., Berendse HW; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands.; Department of Neurology, Amsterdam UMC, Amsterdam, The Netherlands., Rozemuller AJ; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands.; Department of Pathology, Amsterdam UMC, Amsterdam, The Netherlands., Bugiani M; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands.; Department of Pathology, Amsterdam UMC, Amsterdam, The Netherlands., Kustermann T; Roche Pharma Research and Early Development, Neuroscience and Rare Diseases Discovery and Translational Area, Biomarker, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland., Machado V; Roche Pharma Research and Early Development, Neuroscience and Rare Diseases Discovery and Translational Area, Biomarker, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland., Britschgi M; Roche Pharma Research and Early Development, Neuroscience and Rare Diseases Discovery and Translational Area, Research, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland., van de Berg WD; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands.
Source: Journal of Parkinson's disease [J Parkinsons Dis] 2026 May; Vol. 16 (3), pp. 438-451. Date of Electronic Publication: 2026 Feb 26.
Publication Type: Journal Article
Journal Info: Publisher: IOS Press Country of Publication: United States NLM ID: 101567362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1877-718X (Electronic) Linking ISSN: 18777171 NLM ISO Abbreviation: J Parkinsons Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Quantitative measures of total and phosphorylated alpha-synuclein in skin tissue as potential biomarkers for synucleinopathies.
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  Data: <searchLink fieldCode="AU" term="%22van+der+Gaag+BL%22">van der Gaag BL</searchLink>; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Wetering+J%22">van Wetering J</searchLink>; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Morella+ML%22">Morella ML</searchLink>; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Breve+JJ%22">Breve JJ</searchLink>; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Reijner+N%22">Reijner N</searchLink>; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Pfeifer+J%22">Pfeifer J</searchLink>; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Delft University of Technology, Delft, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Simando+A+3rd%22">Simando A 3rd</searchLink>; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Department of Biology, De La Salle University, Manila, Philippines.; St. Luke's Medical Center College of Medicine - William H. Quasha Memorial, Quezon City, Philippines.<br /><searchLink fieldCode="AU" term="%22van+Hilten+JJ%22">van Hilten JJ</searchLink>; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Berendse+HW%22">Berendse HW</searchLink>; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands.; Department of Neurology, Amsterdam UMC, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rozemuller+AJ%22">Rozemuller AJ</searchLink>; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands.; Department of Pathology, Amsterdam UMC, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bugiani+M%22">Bugiani M</searchLink>; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands.; Department of Pathology, Amsterdam UMC, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kustermann+T%22">Kustermann T</searchLink>; Roche Pharma Research and Early Development, Neuroscience and Rare Diseases Discovery and Translational Area, Biomarker, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Machado+V%22">Machado V</searchLink>; Roche Pharma Research and Early Development, Neuroscience and Rare Diseases Discovery and Translational Area, Biomarker, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Britschgi+M%22">Britschgi M</searchLink>; Roche Pharma Research and Early Development, Neuroscience and Rare Diseases Discovery and Translational Area, Research, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22van+de+Berg+WD%22">van de Berg WD</searchLink>; Department of Anatomy and Neurosciences, section Clinical Neuroanatomy and Biobanking, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Neuroscience, program Neurodegeneration, Amsterdam, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%22101567362%22">Journal of Parkinson's disease</searchLink> [J Parkinsons Dis] 2026 May; Vol. 16 (3), pp. 438-451. <i>Date of Electronic Publication: </i>2026 Feb 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22IOS+Press%22">IOS Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101567362 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1877-718X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218777171%22">18777171 </searchLink><i>NLM ISO Abbreviation: </i>J Parkinsons Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1177/1877718X261420669
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