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Activation of Kv7.3 channels in mPFC engram neurons suppresses methamphetamine memory retrieval by reducing excitability and glutamate release in the mPFC-NAc circuit.

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Title: Activation of Kv7.3 channels in mPFC engram neurons suppresses methamphetamine memory retrieval by reducing excitability and glutamate release in the mPFC-NAc circuit.
Authors: Han W; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China.; Department of Health and Life Sciences, University of Health and Rehabilitation Sciences, Qingdao, Shandong, China., Gao Z; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China., Ren Q; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China., Liu E; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China., Tang Y; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China., Yue Y; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China., Wang L; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China., Yue Q; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China., Yu X; Department of Geriatric Medicine & Laboratory of Gerontology and Anti-Aging Research, Qilu Hospital of Shandong University, Jinan, Shandong, China. yuxin2011@email.sdu.edu.cn., Sun J; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China. sunjinhao@sdu.edu.cn.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 Feb 26; Vol. 83 (1). Date of Electronic Publication: 2026 Feb 26.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Activation of Kv7.3 channels in mPFC engram neurons suppresses methamphetamine memory retrieval by reducing excitability and glutamate release in the mPFC-NAc circuit.
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  Data: <searchLink fieldCode="AU" term="%22Han+W%22">Han W</searchLink>; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China.; Department of Health and Life Sciences, University of Health and Rehabilitation Sciences, Qingdao, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Gao+Z%22">Gao Z</searchLink>; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Ren+Q%22">Ren Q</searchLink>; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Liu+E%22">Liu E</searchLink>; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Tang+Y%22">Tang Y</searchLink>; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Yue+Y%22">Yue Y</searchLink>; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Yue+Q%22">Yue Q</searchLink>; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China.<br /><searchLink fieldCode="AU" term="%22Yu+X%22">Yu X</searchLink>; Department of Geriatric Medicine & Laboratory of Gerontology and Anti-Aging Research, Qilu Hospital of Shandong University, Jinan, Shandong, China. yuxin2011@email.sdu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Sun+J%22">Sun J</searchLink>; Department of Anatomy and Neurobiology, Shandong University School of Basic Medicine, Jinan, Shandong, China. sunjinhao@sdu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%229705402%22">Cellular and molecular life sciences : CMLS</searchLink> [Cell Mol Life Sci] 2026 Feb 26; Vol. 83 (1). <i>Date of Electronic Publication: </i>2026 Feb 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>9705402 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1420-9071 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221420682X%22">1420682X </searchLink><i>NLM ISO Abbreviation: </i>Cell Mol Life Sci <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s00018-026-06127-y
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        Text: English
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      – TitleFull: Activation of Kv7.3 channels in mPFC engram neurons suppresses methamphetamine memory retrieval by reducing excitability and glutamate release in the mPFC-NAc circuit.
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              Text: 2026 Feb 26
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              Y: 2026
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