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PD-1 protects expanding human T cells from premature restimulation-induced cell death by modulating TCR and CD28 signaling.

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Title: PD-1 protects expanding human T cells from premature restimulation-induced cell death by modulating TCR and CD28 signaling.
Authors: Lee KP; Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Elster S; Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Epstein B; Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Lake CM; Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA., Snow AL; Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. andrew.snow@usuhs.edu.
Source: Cell death & disease [Cell Death Dis] 2026 Feb 26; Vol. 17 (1). Date of Electronic Publication: 2026 Feb 26.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PD-1 protects expanding human T cells from premature restimulation-induced cell death by modulating TCR and CD28 signaling.
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  Data: <searchLink fieldCode="AU" term="%22Lee+KP%22">Lee KP</searchLink>; Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Elster+S%22">Elster S</searchLink>; Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Epstein+B%22">Epstein B</searchLink>; Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lake+CM%22">Lake CM</searchLink>; Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Snow+AL%22">Snow AL</searchLink>; Department of Pharmacology & Molecular Therapeutics, Uniformed Services University of the Health Sciences, Bethesda, MD, USA. andrew.snow@usuhs.edu.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2026 Feb 26; Vol. 17 (1). <i>Date of Electronic Publication: </i>2026 Feb 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s41419-026-08530-6
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      – TitleFull: PD-1 protects expanding human T cells from premature restimulation-induced cell death by modulating TCR and CD28 signaling.
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              Text: 2026 Feb 26
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