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Mitochondria contact lipid droplets through the mitochondrial import complex binding to lipid metabolism enzyme Ayr1.

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Title: Mitochondria contact lipid droplets through the mitochondrial import complex binding to lipid metabolism enzyme Ayr1.
Authors: Heinen S; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany., Tiku V; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany., Grevel A; Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Hugenroth M; Institute of Cell Dynamics and Imaging, University of Münster, Münster, Germany.; Cells in Motion Interfaculty Centre, University of Münster, Münster, Germany., Ellenrieder L; Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Novartis Pharma AG, Basel, Switzerland., Steymans I; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany., Licheva M; Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Bonini S; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany., Oeljeklaus S; Department of Biochemistry II, Theodor-Boveri-Institute, Biocenter, Faculty of Chemistry and Pharmacy, University of Würzburg, Würzburg, Germany., Okon N; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany., Lambertz J; Institute of Neuroanatomy, Faculty of Medicine, University of Bonn, Bonn, Germany., Poppe S; Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Song J; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany., Fester L; Institute of Neuroanatomy, Faculty of Medicine, University of Bonn, Bonn, Germany., Meisinger C; Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; CIBSS Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.; BIOSS Centre for Biological Signalling Studies, University of Freiburg, Freiburg, Germany., Warscheid B; Department of Biochemistry II, Theodor-Boveri-Institute, Biocenter, Faculty of Chemistry and Pharmacy, University of Würzburg, Würzburg, Germany., Eckhardt M; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany., Wiedemann N; Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; CIBSS Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.; BIOSS Centre for Biological Signalling Studies, University of Freiburg, Freiburg, Germany., Winter D; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany., Kraft C; Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; CIBSS Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany., den Brave F; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany., Bohnert M; Institute of Cell Dynamics and Imaging, University of Münster, Münster, Germany.; Cells in Motion Interfaculty Centre, University of Münster, Münster, Germany., Pfanner N; Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany. nikolaus.pfanner@biochemie.uni-freiburg.de.; CIBSS Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany. nikolaus.pfanner@biochemie.uni-freiburg.de.; BIOSS Centre for Biological Signalling Studies, University of Freiburg, Freiburg, Germany. nikolaus.pfanner@biochemie.uni-freiburg.de., Becker T; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany. thbecker@uni-bonn.de.
Source: Nature cell biology [Nat Cell Biol] 2026 Mar; Vol. 28 (3), pp. 436-448. Date of Electronic Publication: 2026 Feb 26.
Publication Type: Journal Article
Journal Info: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE
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  Data: Mitochondria contact lipid droplets through the mitochondrial import complex binding to lipid metabolism enzyme Ayr1.
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  Data: <searchLink fieldCode="AU" term="%22Heinen+S%22">Heinen S</searchLink>; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Tiku+V%22">Tiku V</searchLink>; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Grevel+A%22">Grevel A</searchLink>; Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hugenroth+M%22">Hugenroth M</searchLink>; Institute of Cell Dynamics and Imaging, University of Münster, Münster, Germany.; Cells in Motion Interfaculty Centre, University of Münster, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Ellenrieder+L%22">Ellenrieder L</searchLink>; Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; 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Institute of Neuroanatomy, Faculty of Medicine, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Poppe+S%22">Poppe S</searchLink>; Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Song+J%22">Song J</searchLink>; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Fester+L%22">Fester L</searchLink>; Institute of Neuroanatomy, Faculty of Medicine, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Meisinger+C%22">Meisinger C</searchLink>; Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; CIBSS Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.; BIOSS Centre for Biological Signalling Studies, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Warscheid+B%22">Warscheid B</searchLink>; Department of Biochemistry II, Theodor-Boveri-Institute, Biocenter, Faculty of Chemistry and Pharmacy, University of Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Eckhardt+M%22">Eckhardt M</searchLink>; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Wiedemann+N%22">Wiedemann N</searchLink>; Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; CIBSS Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany.; BIOSS Centre for Biological Signalling Studies, University of Freiburg, Freiburg, Germany.<br /><searchLink fieldCode="AU" term="%22Winter+D%22">Winter D</searchLink>; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Kraft+C%22">Kraft C</searchLink>; Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; 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Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Bonn, Bonn, Germany. thbecker@uni-bonn.de.
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