Kynurenine pathway dysregulation in major depressive disorder: the convergence of excitotoxicity, neuroinflammation, and oxidative stress.
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| Title: | Kynurenine pathway dysregulation in major depressive disorder: the convergence of excitotoxicity, neuroinflammation, and oxidative stress. |
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| Authors: | O'Regan G; School of Medical Sciences, University of Victoria, Victoria, BC, Canada., Plummer Z; School of Medical Sciences, University of Victoria, Victoria, BC, Canada., Christie BR; School of Medical Sciences, University of Victoria, Victoria, BC, Canada.; Island Medical Program, University of British Columbia, Victoria, BC, Canada.; Institute for Aging and Lifelong Health, University of Victoria, Victoria, BC, Canada.; Center for Behavioural Teratology, San Diego State University, San Diego, CA, USA., Shultz SR; School of Medical Sciences, University of Victoria, Victoria, BC, Canada.; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, VIC, Australia.; Centre for Trauma and Mental Health Research, Vancouver Island University, Nanaimo, BC, Canada., Allen J; School of Medical Sciences, University of Victoria, Victoria, BC, Canada. joshua.allen@viu.ca.; Institute for Aging and Lifelong Health, University of Victoria, Victoria, BC, Canada. joshua.allen@viu.ca.; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, VIC, Australia. joshua.allen@viu.ca.; Centre for Trauma and Mental Health Research, Vancouver Island University, Nanaimo, BC, Canada. joshua.allen@viu.ca.; The Clinical Psychedelic Lab, Monash University, Notting Hill, Melbourne, VIC, Australia. joshua.allen@viu.ca. |
| Source: | Journal of neuroinflammation [J Neuroinflammation] 2026 Feb 26; Vol. 23 (1). Date of Electronic Publication: 2026 Feb 26. |
| Publication Type: | Journal Article; Review |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094 (Electronic) Linking ISSN: 17422094 NLM ISO Abbreviation: J Neuroinflammation Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41749295 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Kynurenine pathway dysregulation in major depressive disorder: the convergence of excitotoxicity, neuroinflammation, and oxidative stress. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22O'Regan+G%22">O'Regan G</searchLink>; School of Medical Sciences, University of Victoria, Victoria, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Plummer+Z%22">Plummer Z</searchLink>; School of Medical Sciences, University of Victoria, Victoria, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Christie+BR%22">Christie BR</searchLink>; School of Medical Sciences, University of Victoria, Victoria, BC, Canada.; Island Medical Program, University of British Columbia, Victoria, BC, Canada.; Institute for Aging and Lifelong Health, University of Victoria, Victoria, BC, Canada.; Center for Behavioural Teratology, San Diego State University, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Shultz+SR%22">Shultz SR</searchLink>; School of Medical Sciences, University of Victoria, Victoria, BC, Canada.; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, VIC, Australia.; Centre for Trauma and Mental Health Research, Vancouver Island University, Nanaimo, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Allen+J%22">Allen J</searchLink>; School of Medical Sciences, University of Victoria, Victoria, BC, Canada. joshua.allen@viu.ca.; Institute for Aging and Lifelong Health, University of Victoria, Victoria, BC, Canada. joshua.allen@viu.ca.; Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, VIC, Australia. joshua.allen@viu.ca.; Centre for Trauma and Mental Health Research, Vancouver Island University, Nanaimo, BC, Canada. joshua.allen@viu.ca.; The Clinical Psychedelic Lab, Monash University, Notting Hill, Melbourne, VIC, Australia. joshua.allen@viu.ca. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101222974%22">Journal of neuroinflammation</searchLink> [J Neuroinflammation] 2026 Feb 26; Vol. 23 (1). <i>Date of Electronic Publication: </i>2026 Feb 26. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Review – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101222974 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1742-2094 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217422094%22">17422094 </searchLink><i>NLM ISO Abbreviation: </i>J Neuroinflammation <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41749295 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s12974-026-03717-2 Languages: – Code: eng Text: English Titles: – TitleFull: Kynurenine pathway dysregulation in major depressive disorder: the convergence of excitotoxicity, neuroinflammation, and oxidative stress. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: O'Regan G – PersonEntity: Name: NameFull: Plummer Z – PersonEntity: Name: NameFull: Christie BR – PersonEntity: Name: NameFull: Shultz SR – PersonEntity: Name: NameFull: Allen J IsPartOfRelationships: – BibEntity: Dates: – D: 26 M: 02 Text: 2026 Feb 26 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1742-2094 Numbering: – Type: volume Value: 23 – Type: issue Value: 1 Titles: – TitleFull: Journal of neuroinflammation Type: main |
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