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Increasing the Response of Mismatch Repair Proficient Rectal Cancer to Immunotherapy with Particle Radiation and DNA Damage Response Inhibitors-Preclinical Evidence.

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Title: Increasing the Response of Mismatch Repair Proficient Rectal Cancer to Immunotherapy with Particle Radiation and DNA Damage Response Inhibitors-Preclinical Evidence.
Authors: Salazar-Vilches CJ; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Ebner DK; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Kloeber JA; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Dragojevic S; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Singh J; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Haddock M; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Sharifzadeh Y; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Sherry AD; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Jethwa KR; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Hallemeier CL; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Merrell KW; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Mutter RW; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA., Lou Z; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA., Callaghan CM; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.
Source: Cancers [Cancers (Basel)] 2026 Feb 19; Vol. 18 (4). Date of Electronic Publication: 2026 Feb 19.
Publication Type: Journal Article; Review
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Increasing the Response of Mismatch Repair Proficient Rectal Cancer to Immunotherapy with Particle Radiation and DNA Damage Response Inhibitors-Preclinical Evidence.
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  Data: <searchLink fieldCode="AU" term="%22Salazar-Vilches+CJ%22">Salazar-Vilches CJ</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Ebner+DK%22">Ebner DK</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Kloeber+JA%22">Kloeber JA</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Dragojevic+S%22">Dragojevic S</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Singh+J%22">Singh J</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Haddock+M%22">Haddock M</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Sharifzadeh+Y%22">Sharifzadeh Y</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Sherry+AD%22">Sherry AD</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Jethwa+KR%22">Jethwa KR</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Hallemeier+CL%22">Hallemeier CL</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Merrell+KW%22">Merrell KW</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Mutter+RW%22">Mutter RW</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Lou+Z%22">Lou Z</searchLink>; Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA.<br /><searchLink fieldCode="AU" term="%22Callaghan+CM%22">Callaghan CM</searchLink>; Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA.
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  Data: <searchLink fieldCode="JN" term="%22101526829%22">Cancers</searchLink> [Cancers (Basel)] 2026 Feb 19; Vol. 18 (4). <i>Date of Electronic Publication: </i>2026 Feb 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI%22">MDPI </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101526829 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2072-6694 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220726694%22">20726694 </searchLink><i>NLM ISO Abbreviation: </i>Cancers (Basel) <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 Feb 19
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