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Development of a Radiotherapy-Induced Wound Model in Wistar Rats: Simulating Post-Radiation Skin and Soft Tissue Complications for Therapeutic Evaluation.

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Title: Development of a Radiotherapy-Induced Wound Model in Wistar Rats: Simulating Post-Radiation Skin and Soft Tissue Complications for Therapeutic Evaluation.
Authors: Avadanei-Luca S; Department of Plastic Surgery, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania., Tamba BI; Department of Pharmacology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.; Center for Advanced Research and Development in Experimental Medicine (CEMEX), 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania., Draga Caruntu I; Department of Morpho-Functional Sciences I, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.; Romanian Medical Science Academy, 030167 Bucharest, Romania., Giusca SE; Department of Morpho-Functional Sciences I, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania., Timofte AD; Department of Morpho-Functional Sciences I, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania., Szilagyi A; Center for Advanced Research and Development in Experimental Medicine (CEMEX), 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania., Costachescu I; Center for Advanced Research and Development in Experimental Medicine (CEMEX), 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania., Gogu MR; Center for Advanced Research and Development in Experimental Medicine (CEMEX), 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania., Avadanei AN; Department of Vascular Surgery, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania., Pertea M; Department of Plastic Surgery, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania., Benamor M; Department of Plastic Surgery, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania., Cojocaru ID; Elytis Radiotherapy and Oncology Center, 700714 Iasi, Romania., Ciofu ML; Department of Oral and Maxillo-Facial Surgery, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania., Scripcariu V; Department of General Surgery, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.
Source: Biomedicines [Biomedicines] 2026 Feb 12; Vol. 14 (2). Date of Electronic Publication: 2026 Feb 12.
Publication Type: Journal Article
Journal Info: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101691304 Publication Model: Electronic Cited Medium: Print ISSN: 2227-9059 (Print) Linking ISSN: 22279059 NLM ISO Abbreviation: Biomedicines Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Development of a Radiotherapy-Induced Wound Model in Wistar Rats: Simulating Post-Radiation Skin and Soft Tissue Complications for Therapeutic Evaluation.
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  Data: <searchLink fieldCode="AU" term="%22Avadanei-Luca+S%22">Avadanei-Luca S</searchLink>; Department of Plastic Surgery, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.<br /><searchLink fieldCode="AU" term="%22Tamba+BI%22">Tamba BI</searchLink>; Department of Pharmacology, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.; Center for Advanced Research and Development in Experimental Medicine (CEMEX), 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.<br /><searchLink fieldCode="AU" term="%22Draga+Caruntu+I%22">Draga Caruntu I</searchLink>; Department of Morpho-Functional Sciences I, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.; Romanian Medical Science Academy, 030167 Bucharest, Romania.<br /><searchLink fieldCode="AU" term="%22Giusca+SE%22">Giusca SE</searchLink>; Department of Morpho-Functional Sciences I, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.<br /><searchLink fieldCode="AU" term="%22Timofte+AD%22">Timofte AD</searchLink>; Department of Morpho-Functional Sciences I, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.<br /><searchLink fieldCode="AU" term="%22Szilagyi+A%22">Szilagyi A</searchLink>; Center for Advanced Research and Development in Experimental Medicine (CEMEX), 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.<br /><searchLink fieldCode="AU" term="%22Costachescu+I%22">Costachescu I</searchLink>; Center for Advanced Research and Development in Experimental Medicine (CEMEX), 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.<br /><searchLink fieldCode="AU" term="%22Gogu+MR%22">Gogu MR</searchLink>; Center for Advanced Research and Development in Experimental Medicine (CEMEX), 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.<br /><searchLink fieldCode="AU" term="%22Avadanei+AN%22">Avadanei AN</searchLink>; Department of Vascular Surgery, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.<br /><searchLink fieldCode="AU" term="%22Pertea+M%22">Pertea M</searchLink>; Department of Plastic Surgery, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.<br /><searchLink fieldCode="AU" term="%22Benamor+M%22">Benamor M</searchLink>; Department of Plastic Surgery, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.<br /><searchLink fieldCode="AU" term="%22Cojocaru+ID%22">Cojocaru ID</searchLink>; Elytis Radiotherapy and Oncology Center, 700714 Iasi, Romania.<br /><searchLink fieldCode="AU" term="%22Ciofu+ML%22">Ciofu ML</searchLink>; Department of Oral and Maxillo-Facial Surgery, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.<br /><searchLink fieldCode="AU" term="%22Scripcariu+V%22">Scripcariu V</searchLink>; Department of General Surgery, 'Grigore T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.
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  Data: <searchLink fieldCode="JN" term="%22101691304%22">Biomedicines</searchLink> [Biomedicines] 2026 Feb 12; Vol. 14 (2). <i>Date of Electronic Publication: </i>2026 Feb 12.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI+AG%22">MDPI AG </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101691304 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2227-9059 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222279059%22">22279059 </searchLink><i>NLM ISO Abbreviation: </i>Biomedicines <i>Subsets: </i>PubMed not MEDLINE
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              Text: 2026 Feb 12
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