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Targeting TRPA1 with Novel Synthetic Compounds Based on Different Scaffolds to Reduce Acute and Chronic Pain.

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Title: Targeting TRPA1 with Novel Synthetic Compounds Based on Different Scaffolds to Reduce Acute and Chronic Pain.
Authors: Corallo AA; Department of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy., Maramai S; Department of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy., Noli C; Department of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy., Paolino M; Department of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy., Brizzi A; Department of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy., Ligresti A; Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Italy., Allarà M; Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Italy., De Petrocellis L; Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Italy., Vitale RM; Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Italy., Schiano Moriello A; Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Italy.; Epitech Group SpA, Saccolongo, 35100 Padova, Italy., Belardo C; Department of Experimental Medicine, Division of Pharmacology, Università degli Studi della Campania 'L. Vanvitelli', 80138 Naples, Italy., Infantino R; Department of Experimental Medicine, Division of Pharmacology, Università degli Studi della Campania 'L. Vanvitelli', 80138 Naples, Italy., Maione S; Department of Experimental Medicine, Division of Pharmacology, Università degli Studi della Campania 'L. Vanvitelli', 80138 Naples, Italy., Mugnaini C; Department of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy., Corelli F; Department of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy.
Source: International journal of molecular sciences [Int J Mol Sci] 2026 Feb 10; Vol. 27 (4). Date of Electronic Publication: 2026 Feb 10.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting TRPA1 with Novel Synthetic Compounds Based on Different Scaffolds to Reduce Acute and Chronic Pain.
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  Data: <searchLink fieldCode="AU" term="%22Corallo+AA%22">Corallo AA</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Maramai+S%22">Maramai S</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Noli+C%22">Noli C</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Paolino+M%22">Paolino M</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Brizzi+A%22">Brizzi A</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Ligresti+A%22">Ligresti A</searchLink>; Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Italy.<br /><searchLink fieldCode="AU" term="%22Allarà+M%22">Allarà M</searchLink>; Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Italy.<br /><searchLink fieldCode="AU" term="%22De+Petrocellis+L%22">De Petrocellis L</searchLink>; Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Italy.<br /><searchLink fieldCode="AU" term="%22Vitale+RM%22">Vitale RM</searchLink>; Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Italy.<br /><searchLink fieldCode="AU" term="%22Schiano+Moriello+A%22">Schiano Moriello A</searchLink>; Institute of Biomolecular Chemistry, Consiglio Nazionale delle Ricerche, 80078 Pozzuoli, Italy.; Epitech Group SpA, Saccolongo, 35100 Padova, Italy.<br /><searchLink fieldCode="AU" term="%22Belardo+C%22">Belardo C</searchLink>; Department of Experimental Medicine, Division of Pharmacology, Università degli Studi della Campania 'L. Vanvitelli', 80138 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Infantino+R%22">Infantino R</searchLink>; Department of Experimental Medicine, Division of Pharmacology, Università degli Studi della Campania 'L. Vanvitelli', 80138 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Maione+S%22">Maione S</searchLink>; Department of Experimental Medicine, Division of Pharmacology, Università degli Studi della Campania 'L. Vanvitelli', 80138 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Mugnaini+C%22">Mugnaini C</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Corelli+F%22">Corelli F</searchLink>; Department of Biotechnology, Chemistry and Pharmacy, Università di Siena, Via A. Moro 2, 53100 Siena, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101092791%22">International journal of molecular sciences</searchLink> [Int J Mol Sci] 2026 Feb 10; Vol. 27 (4). <i>Date of Electronic Publication: </i>2026 Feb 10.
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