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A pilot, parallel-group, blinded, placebo-controlled, randomiseD, pRagmatic clinical trial investigating the Effect of temazepAM on objective and subjective measures of sleep in critically ill patients (the DREAM trial).

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Title: A pilot, parallel-group, blinded, placebo-controlled, randomiseD, pRagmatic clinical trial investigating the Effect of temazepAM on objective and subjective measures of sleep in critically ill patients (the DREAM trial).
Authors: Showler L; Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, Cnr Grattan Street & Royal Parade, Parkville, Melbourne, Victoria, Australia.; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia., Ali Abdelhamid Y; Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, Cnr Grattan Street & Royal Parade, Parkville, Melbourne, Victoria, Australia.; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia., Ankravs MJ; Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, Cnr Grattan Street & Royal Parade, Parkville, Melbourne, Victoria, Australia.; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.; Department of Pharmacy, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia., Goldin J; Department of Respiratory and Sleep Disorders Medicine, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia., Plummer MP; Department of Intensive Care, Royal Adelaide Hospital, Port Road, Adelaide, South Australia, Australia.; Adelaide Medical School, The University of Adelaide, 4 North Terrace, Adelaide, South Australia, Australia., Tascone B; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia., Byrne K; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia., Perkins A; Department of Respiratory and Sleep Disorders Medicine, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia., Kee K; Department of Respiratory and Sleep Disorders Medicine, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.; The School of Translational Medicine, Monash University, 99 Commercial Road, Melbourne, Victoria, Australia., Moore C; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia., Johnston B; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia., Presneill J; Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, Cnr Grattan Street & Royal Parade, Parkville, Melbourne, Victoria, Australia.; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia., Deane AM; Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, Cnr Grattan Street & Royal Parade, Parkville, Melbourne, Victoria, Australia.; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.
Source: Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine [Crit Care Resusc] 2026 Feb 19; Vol. 28 (1), pp. 100169. Date of Electronic Publication: 2026 Feb 19 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V. on behalf of College of Intensive Care Medicine of Australia and New Zealand Country of Publication: Netherlands NLM ID: 100888170 Publication Model: eCollection Cited Medium: Print ISSN: 1441-2772 (Print) Linking ISSN: 14412772 NLM ISO Abbreviation: Crit Care Resusc Subsets: In Process
Database: MEDLINE Ultimate
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  Data: A pilot, parallel-group, blinded, placebo-controlled, randomiseD, pRagmatic clinical trial investigating the Effect of temazepAM on objective and subjective measures of sleep in critically ill patients (the DREAM trial).
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  Data: <searchLink fieldCode="AU" term="%22Showler+L%22">Showler L</searchLink>; Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, Cnr Grattan Street & Royal Parade, Parkville, Melbourne, Victoria, Australia.; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Ali+Abdelhamid+Y%22">Ali Abdelhamid Y</searchLink>; Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, Cnr Grattan Street & Royal Parade, Parkville, Melbourne, Victoria, Australia.; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Ankravs+MJ%22">Ankravs MJ</searchLink>; Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, Cnr Grattan Street & Royal Parade, Parkville, Melbourne, Victoria, Australia.; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.; Department of Pharmacy, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Goldin+J%22">Goldin J</searchLink>; Department of Respiratory and Sleep Disorders Medicine, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Plummer+MP%22">Plummer MP</searchLink>; Department of Intensive Care, Royal Adelaide Hospital, Port Road, Adelaide, South Australia, Australia.; Adelaide Medical School, The University of Adelaide, 4 North Terrace, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Tascone+B%22">Tascone B</searchLink>; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Byrne+K%22">Byrne K</searchLink>; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Perkins+A%22">Perkins A</searchLink>; Department of Respiratory and Sleep Disorders Medicine, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Kee+K%22">Kee K</searchLink>; Department of Respiratory and Sleep Disorders Medicine, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.; The School of Translational Medicine, Monash University, 99 Commercial Road, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Moore+C%22">Moore C</searchLink>; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Johnston+B%22">Johnston B</searchLink>; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Presneill+J%22">Presneill J</searchLink>; Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, Cnr Grattan Street & Royal Parade, Parkville, Melbourne, Victoria, Australia.; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Deane+AM%22">Deane AM</searchLink>; Department of Critical Care, Melbourne Medical School, University of Melbourne, Melbourne, Cnr Grattan Street & Royal Parade, Parkville, Melbourne, Victoria, Australia.; Department of Intensive Care, The Royal Melbourne Hospital, 300 Grattan Street, Parkville, Melbourne, Victoria, Australia.
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