Long noncoding RNA X-inactive-specific transcript promotes hepatic fibrosis by suppressing ferroptosis in hepatic stellate cells via the miR-663a/GPX4 axis.

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Title: Long noncoding RNA X-inactive-specific transcript promotes hepatic fibrosis by suppressing ferroptosis in hepatic stellate cells via the miR-663a/GPX4 axis.
Authors: Dai J; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China., Zhong GH; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China., Yang JX; Department of Hepatobiliary and Pancreatic Surgery, Central People's Hospital of Zhanjiang, Zhanjiang, Guangdong, China., Tan XY; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China., Dai D; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China., Li MY; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Source: Frontiers in physiology [Front Physiol] 2026 Feb 11; Vol. 16, pp. 1734886. Date of Electronic Publication: 2026 Feb 11 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101549006 Publication Model: eCollection Cited Medium: Print ISSN: 1664-042X (Print) Linking ISSN: 1664042X NLM ISO Abbreviation: Front Physiol Subsets: PubMed not MEDLINE
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  Data: Long noncoding RNA X-inactive-specific transcript promotes hepatic fibrosis by suppressing ferroptosis in hepatic stellate cells via the miR-663a/GPX4 axis.
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  Data: <searchLink fieldCode="AU" term="%22Dai+J%22">Dai J</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zhong+GH%22">Zhong GH</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Yang+JX%22">Yang JX</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Central People's Hospital of Zhanjiang, Zhanjiang, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Tan+XY%22">Tan XY</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Dai+D%22">Dai D</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Li+MY%22">Li MY</searchLink>; Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
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  Data: <searchLink fieldCode="JN" term="%22101549006%22">Frontiers in physiology</searchLink> [Front Physiol] 2026 Feb 11; Vol. 16, pp. 1734886. <i>Date of Electronic Publication: </i>2026 Feb 11 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation%22">Frontiers Research Foundation </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101549006 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1664-042X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221664042X%22">1664042X </searchLink><i>NLM ISO Abbreviation: </i>Front Physiol <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.3389/fphys.2025.1734886
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        Text: English
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      – TitleFull: Long noncoding RNA X-inactive-specific transcript promotes hepatic fibrosis by suppressing ferroptosis in hepatic stellate cells via the miR-663a/GPX4 axis.
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              Text: 2026 Feb 11
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