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The impact of seizures on REM sleep and the cholinergic pedunculopontine nucleus in a mouse model of Dravet Syndrome.

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Title: The impact of seizures on REM sleep and the cholinergic pedunculopontine nucleus in a mouse model of Dravet Syndrome.
Authors: Santiago-Colon KM; Department of Pharmacology, University of Michigan, Ann Arbor, MI USA., Rana C; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI USA., Toth B; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI USA., Kravchenko JA; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI USA., Barden J; Department of Neurology, University of Michigan, Ann Arbor, MI USA., VanHorn I; Department of Neurology, University of Michigan, Ann Arbor, MI USA., Jack A; Department of Neurology, University of Michigan, Ann Arbor, MI USA., Hollier A; Department of Neurology, University of Michigan, Ann Arbor, MI USA., Qureshi R; Department of Neurology, University of Michigan, Ann Arbor, MI USA., Haberland H; Department of Neurology, University of Michigan, Ann Arbor, MI USA., Disla J; Department of Neurology, University of Michigan, Ann Arbor, MI USA., Eldroubi N; Department of Neurology, University of Michigan, Ann Arbor, MI USA., Siddiqui S; Department of Neurology, University of Michigan, Ann Arbor, MI USA., Erb-Watson S; Department of Neurology, University of Michigan, Ann Arbor, MI USA., Burgess C; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI USA.; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI USA.; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI USA., Isom LL; Department of Pharmacology, University of Michigan, Ann Arbor, MI USA.; Department of Neurology, University of Michigan, Ann Arbor, MI USA.; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI USA., Mattis J; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI USA.; Department of Neurology, University of Michigan, Ann Arbor, MI USA.; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI USA.; VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Feb 18. Date of Electronic Publication: 2026 Feb 18.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: The impact of seizures on REM sleep and the cholinergic pedunculopontine nucleus in a mouse model of Dravet Syndrome.
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  Data: <searchLink fieldCode="AU" term="%22Santiago-Colon+KM%22">Santiago-Colon KM</searchLink>; Department of Pharmacology, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22Rana+C%22">Rana C</searchLink>; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22Toth+B%22">Toth B</searchLink>; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22Kravchenko+JA%22">Kravchenko JA</searchLink>; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22Barden+J%22">Barden J</searchLink>; Department of Neurology, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22VanHorn+I%22">VanHorn I</searchLink>; Department of Neurology, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22Jack+A%22">Jack A</searchLink>; Department of Neurology, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22Hollier+A%22">Hollier A</searchLink>; Department of Neurology, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22Qureshi+R%22">Qureshi R</searchLink>; Department of Neurology, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22Haberland+H%22">Haberland H</searchLink>; Department of Neurology, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22Disla+J%22">Disla J</searchLink>; Department of Neurology, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22Eldroubi+N%22">Eldroubi N</searchLink>; Department of Neurology, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22Siddiqui+S%22">Siddiqui S</searchLink>; Department of Neurology, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22Erb-Watson+S%22">Erb-Watson S</searchLink>; Department of Neurology, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22Burgess+C%22">Burgess C</searchLink>; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI USA.; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI USA.; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22Isom+LL%22">Isom LL</searchLink>; Department of Pharmacology, University of Michigan, Ann Arbor, MI USA.; Department of Neurology, University of Michigan, Ann Arbor, MI USA.; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI USA.<br /><searchLink fieldCode="AU" term="%22Mattis+J%22">Mattis J</searchLink>; Neuroscience Graduate Program, University of Michigan, Ann Arbor, MI USA.; Department of Neurology, University of Michigan, Ann Arbor, MI USA.; Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI USA.; VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA.
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              Text: 2026 Feb 18
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