View in EDS

Excessive Ca2+-dependent ER-mitochondrial contact stabilization by EFHD1 drives liver injury.

Saved in:
Bibliographic Details
Title: Excessive Ca2+-dependent ER-mitochondrial contact stabilization by EFHD1 drives liver injury.
Authors: Eberhardt DR; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Rekate EC; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Masini YB; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Duron HE; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Mollinedo D; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Velarde AM; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Stucki D; Department of Internal Medicine, Division of Nephrology and Hypertension, University of Utah, Salt Lake City, UT., Price T; Department of Internal Medicine, Division of Nephrology and Hypertension, University of Utah, Salt Lake City, UT., Lee SHJ; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Balderas E; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Rai NK; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Bratt AR; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Balynas AM; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Stubben CJ; Bioinformatics Shared Resource, Huntsman Cancer Institute, Salt Lake City, UT., Bia R; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Maity S; Thermo Fisher Scientific, San Jose, CA., Hartel N; Thermo Fisher Scientific, San Jose, CA., Yin X; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Corbin A; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Kumari A; Department of Pharmacology and Physiology, University of Maryland School of Medicine, Baltimore, MD., Nguyen DM; Department of Pharmacology and Physiology, University of Maryland School of Medicine, Baltimore, MD., Shimura D; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Nguyen VD; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT., Vinod V; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT., Chowdhury KH; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT., Verdeguer F; InSphero AG, Schlieren, Switzerland., Zvick J; InSphero AG, Schlieren, Switzerland., Mimche PN; Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN., Boudina S; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT., Drakos SG; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, UT., Aromolaran AS; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT.; Department of Surgery, Division of Cardiothoracic Surgery, University of Utah, Salt Lake City, UT.; Departments of Biochemistry and Biomedical Engineering, University of Utah, Salt Lake City, UT., Franklin S; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, UT., Garg V; Department of Pharmacology and Physiology, University of Maryland School of Medicine, Baltimore, MD., Shaw RM; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, UT., Holland WL; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT., Summers SA; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT., Pezzolesi MG; Department of Internal Medicine, Division of Nephrology and Hypertension, University of Utah, Salt Lake City, UT.; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT.; Department of Human Genetics, University of Utah, Salt Lake City, UT., Rutter J; Howard Hughes Medical Institute, Department of Biochemistry, University of Utah, Salt Lake City, UT., Evason KJ; Department of Pathology and Huntsman Cancer Institute, University of Utah, Salt Lake City, UT., Chaudhuri D; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, UT.; Departments of Biochemistry and Biomedical Engineering, University of Utah, Salt Lake City, UT.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Feb 16. Date of Electronic Publication: 2026 Feb 16.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41756893
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Excessive Ca<superscript>2+</superscript>-dependent ER-mitochondrial contact stabilization by EFHD1 drives liver injury.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Eberhardt+DR%22">Eberhardt DR</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Rekate+EC%22">Rekate EC</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Masini+YB%22">Masini YB</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Duron+HE%22">Duron HE</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Mollinedo+D%22">Mollinedo D</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Velarde+AM%22">Velarde AM</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Stucki+D%22">Stucki D</searchLink>; Department of Internal Medicine, Division of Nephrology and Hypertension, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Price+T%22">Price T</searchLink>; Department of Internal Medicine, Division of Nephrology and Hypertension, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Lee+SHJ%22">Lee SHJ</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Balderas+E%22">Balderas E</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Rai+NK%22">Rai NK</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Bratt+AR%22">Bratt AR</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Balynas+AM%22">Balynas AM</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Stubben+CJ%22">Stubben CJ</searchLink>; Bioinformatics Shared Resource, Huntsman Cancer Institute, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Bia+R%22">Bia R</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Maity+S%22">Maity S</searchLink>; Thermo Fisher Scientific, San Jose, CA.<br /><searchLink fieldCode="AU" term="%22Hartel+N%22">Hartel N</searchLink>; Thermo Fisher Scientific, San Jose, CA.<br /><searchLink fieldCode="AU" term="%22Yin+X%22">Yin X</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Corbin+A%22">Corbin A</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Kumari+A%22">Kumari A</searchLink>; Department of Pharmacology and Physiology, University of Maryland School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Nguyen+DM%22">Nguyen DM</searchLink>; Department of Pharmacology and Physiology, University of Maryland School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Shimura+D%22">Shimura D</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Nguyen+VD%22">Nguyen VD</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Vinod+V%22">Vinod V</searchLink>; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Chowdhury+KH%22">Chowdhury KH</searchLink>; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Verdeguer+F%22">Verdeguer F</searchLink>; InSphero AG, Schlieren, Switzerland.<br /><searchLink fieldCode="AU" term="%22Zvick+J%22">Zvick J</searchLink>; InSphero AG, Schlieren, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mimche+PN%22">Mimche PN</searchLink>; Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Boudina+S%22">Boudina S</searchLink>; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Drakos+SG%22">Drakos SG</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Aromolaran+AS%22">Aromolaran AS</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT.; Department of Surgery, Division of Cardiothoracic Surgery, University of Utah, Salt Lake City, UT.; Departments of Biochemistry and Biomedical Engineering, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Franklin+S%22">Franklin S</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Garg+V%22">Garg V</searchLink>; Department of Pharmacology and Physiology, University of Maryland School of Medicine, Baltimore, MD.<br /><searchLink fieldCode="AU" term="%22Shaw+RM%22">Shaw RM</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Holland+WL%22">Holland WL</searchLink>; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Summers+SA%22">Summers SA</searchLink>; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Pezzolesi+MG%22">Pezzolesi MG</searchLink>; Department of Internal Medicine, Division of Nephrology and Hypertension, University of Utah, Salt Lake City, UT.; Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, UT.; Department of Human Genetics, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Rutter+J%22">Rutter J</searchLink>; Howard Hughes Medical Institute, Department of Biochemistry, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Evason+KJ%22">Evason KJ</searchLink>; Department of Pathology and Huntsman Cancer Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Chaudhuri+D%22">Chaudhuri D</searchLink>; Nora Eccles Harrison Cardiovascular Research and Training Institute, University of Utah, Salt Lake City, UT.; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Utah, Salt Lake City, UT.; Departments of Biochemistry and Biomedical Engineering, University of Utah, Salt Lake City, UT.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 Feb 16. <i>Date of Electronic Publication: </i>2026 Feb 16.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article; Preprint
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41756893
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.64898/2026.02.13.705622
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: Excessive Ca2+-dependent ER-mitochondrial contact stabilization by EFHD1 drives liver injury.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Eberhardt DR
      – PersonEntity:
          Name:
            NameFull: Rekate EC
      – PersonEntity:
          Name:
            NameFull: Masini YB
      – PersonEntity:
          Name:
            NameFull: Duron HE
      – PersonEntity:
          Name:
            NameFull: Mollinedo D
      – PersonEntity:
          Name:
            NameFull: Velarde AM
      – PersonEntity:
          Name:
            NameFull: Stucki D
      – PersonEntity:
          Name:
            NameFull: Price T
      – PersonEntity:
          Name:
            NameFull: Lee SHJ
      – PersonEntity:
          Name:
            NameFull: Balderas E
      – PersonEntity:
          Name:
            NameFull: Rai NK
      – PersonEntity:
          Name:
            NameFull: Bratt AR
      – PersonEntity:
          Name:
            NameFull: Balynas AM
      – PersonEntity:
          Name:
            NameFull: Stubben CJ
      – PersonEntity:
          Name:
            NameFull: Bia R
      – PersonEntity:
          Name:
            NameFull: Maity S
      – PersonEntity:
          Name:
            NameFull: Hartel N
      – PersonEntity:
          Name:
            NameFull: Yin X
      – PersonEntity:
          Name:
            NameFull: Corbin A
      – PersonEntity:
          Name:
            NameFull: Kumari A
      – PersonEntity:
          Name:
            NameFull: Nguyen DM
      – PersonEntity:
          Name:
            NameFull: Shimura D
      – PersonEntity:
          Name:
            NameFull: Nguyen VD
      – PersonEntity:
          Name:
            NameFull: Vinod V
      – PersonEntity:
          Name:
            NameFull: Chowdhury KH
      – PersonEntity:
          Name:
            NameFull: Verdeguer F
      – PersonEntity:
          Name:
            NameFull: Zvick J
      – PersonEntity:
          Name:
            NameFull: Mimche PN
      – PersonEntity:
          Name:
            NameFull: Boudina S
      – PersonEntity:
          Name:
            NameFull: Drakos SG
      – PersonEntity:
          Name:
            NameFull: Aromolaran AS
      – PersonEntity:
          Name:
            NameFull: Franklin S
      – PersonEntity:
          Name:
            NameFull: Garg V
      – PersonEntity:
          Name:
            NameFull: Shaw RM
      – PersonEntity:
          Name:
            NameFull: Holland WL
      – PersonEntity:
          Name:
            NameFull: Summers SA
      – PersonEntity:
          Name:
            NameFull: Pezzolesi MG
      – PersonEntity:
          Name:
            NameFull: Rutter J
      – PersonEntity:
          Name:
            NameFull: Evason KJ
      – PersonEntity:
          Name:
            NameFull: Chaudhuri D
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 16
              M: 02
              Text: 2026 Feb 16
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2692-8205
          Titles:
            – TitleFull: BioRxiv : the preprint server for biology
              Type: main
ResultId 1