Macroscopic to Ultrastructural Analyses Identify the Loss of Myofibrils as the Primary Mediator of Muscle Fiber Atrophy in Aging and Disuse.
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| Title: | Macroscopic to Ultrastructural Analyses Identify the Loss of Myofibrils as the Primary Mediator of Muscle Fiber Atrophy in Aging and Disuse. |
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| Authors: | Sayed RKA; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Sohag University, Sohag, Egypt., Lange AN; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA., Paez HG; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA., Hibbert JE; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA., Meinhold M; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA., Flynn CGK; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA., Vergara MBZ; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA., Dobrzycki I; Exercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, WI, USA.; Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA., Wrucke DJ; Exercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, WI, USA.; Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA., Zepeda CS; Exercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, WI, USA.; Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA., James JJ; Exercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, WI, USA.; Department of Kinesiology, University of Wisconsin-Madison, Madison, WI, USA., Sundberg CW; Exercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, WI, USA.; Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Department of Kinesiology, University of Wisconsin-Madison, Madison, WI, USA.; Athletic and Human Performance Research Center, Marquette University, Milwaukee, WI, USA., Hornberger TA; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2026 Feb 18. Date of Electronic Publication: 2026 Feb 18. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41757020 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Macroscopic to Ultrastructural Analyses Identify the Loss of Myofibrils as the Primary Mediator of Muscle Fiber Atrophy in Aging and Disuse. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Sayed+RKA%22">Sayed RKA</searchLink>; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Sohag University, Sohag, Egypt.<br /><searchLink fieldCode="AU" term="%22Lange+AN%22">Lange AN</searchLink>; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Paez+HG%22">Paez HG</searchLink>; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Hibbert+JE%22">Hibbert JE</searchLink>; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Meinhold+M%22">Meinhold M</searchLink>; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Flynn+CGK%22">Flynn CGK</searchLink>; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Vergara+MBZ%22">Vergara MBZ</searchLink>; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Dobrzycki+I%22">Dobrzycki I</searchLink>; Exercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, WI, USA.; Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Wrucke+DJ%22">Wrucke DJ</searchLink>; Exercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, WI, USA.; Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Zepeda+CS%22">Zepeda CS</searchLink>; Exercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, WI, USA.; Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22James+JJ%22">James JJ</searchLink>; Exercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, WI, USA.; Department of Kinesiology, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Sundberg+CW%22">Sundberg CW</searchLink>; Exercise and Rehabilitation Sciences Program, Department of Physical Therapy, Marquette University, Milwaukee, WI, USA.; Division of Geriatrics and Gerontology, Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA.; Department of Kinesiology, University of Wisconsin-Madison, Madison, WI, USA.; Athletic and Human Performance Research Center, Marquette University, Milwaukee, WI, USA.<br /><searchLink fieldCode="AU" term="%22Hornberger+TA%22">Hornberger TA</searchLink>; Department of Comparative Biosciences, University of Wisconsin-Madison, Madison, WI, USA.; School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101680187%22">BioRxiv : the preprint server for biology</searchLink> [bioRxiv] 2026 Feb 18. <i>Date of Electronic Publication: </i>2026 Feb 18. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Preprint – Name: TitleSource Label: Journal Info Group: Src Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101680187 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2692-8205 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226928205%22">26928205 </searchLink><i>NLM ISO Abbreviation: </i>bioRxiv <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41757020 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.64898/2026.02.16.706166 Languages: – Code: eng Text: English Titles: – TitleFull: Macroscopic to Ultrastructural Analyses Identify the Loss of Myofibrils as the Primary Mediator of Muscle Fiber Atrophy in Aging and Disuse. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Sayed RKA – PersonEntity: Name: NameFull: Lange AN – PersonEntity: Name: NameFull: Paez HG – PersonEntity: Name: NameFull: Hibbert JE – PersonEntity: Name: NameFull: Meinhold M – PersonEntity: Name: NameFull: Flynn CGK – PersonEntity: Name: NameFull: Vergara MBZ – PersonEntity: Name: NameFull: Dobrzycki I – PersonEntity: Name: NameFull: Wrucke DJ – PersonEntity: Name: NameFull: Zepeda CS – PersonEntity: Name: NameFull: James JJ – PersonEntity: Name: NameFull: Sundberg CW – PersonEntity: Name: NameFull: Hornberger TA IsPartOfRelationships: – BibEntity: Dates: – D: 18 M: 02 Text: 2026 Feb 18 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2692-8205 Titles: – TitleFull: BioRxiv : the preprint server for biology Type: main |
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