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G protein Gαq subunits engage targets in the nucleus involved in chromatin remodeling and gene expression.

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Title: G protein Gαq subunits engage targets in the nucleus involved in chromatin remodeling and gene expression.
Authors: Loomis J; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA; Program in Chemical Biology, University of Michigan, Ann Arbor, Michigan, USA., Chandan N; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA; Nurix Therapeutics, San Franscisco, California, USA., Burroughs M; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA., Abraham S; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA., Zhang R; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA., Cao Y; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA., Brody MJ; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA., Tall GG; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA., Smrcka AV; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA; Program in Chemical Biology, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: avsmrcka@umich.edu.
Source: The Journal of biological chemistry [J Biol Chem] 2026 Apr; Vol. 302 (4), pp. 111322. Date of Electronic Publication: 2026 Feb 25.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: G protein Gα<subscript>q</subscript> subunits engage targets in the nucleus involved in chromatin remodeling and gene expression.
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  Data: <searchLink fieldCode="AU" term="%22Loomis+J%22">Loomis J</searchLink>; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA; Program in Chemical Biology, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Chandan+N%22">Chandan N</searchLink>; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA; Nurix Therapeutics, San Franscisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Burroughs+M%22">Burroughs M</searchLink>; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Abraham+S%22">Abraham S</searchLink>; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+R%22">Zhang R</searchLink>; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Cao+Y%22">Cao Y</searchLink>; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Brody+MJ%22">Brody MJ</searchLink>; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Tall+GG%22">Tall GG</searchLink>; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Smrcka+AV%22">Smrcka AV</searchLink>; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA; Program in Chemical Biology, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: avsmrcka@umich.edu.
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  Data: <searchLink fieldCode="JN" term="%222985121R%22">The Journal of biological chemistry</searchLink> [J Biol Chem] 2026 Apr; Vol. 302 (4), pp. 111322. <i>Date of Electronic Publication: </i>2026 Feb 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%2E+on+behalf+of+American+Society+for+Biochemistry+and+Molecular+Biology%22">Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2985121R <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1083-351X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200219258%22">00219258 </searchLink><i>NLM ISO Abbreviation: </i>J Biol Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jbc.2026.111322
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        Text: English
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      – TitleFull: G protein Gαq subunits engage targets in the nucleus involved in chromatin remodeling and gene expression.
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              Text: 2026 Apr
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