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Molecular evolution of animal aging.

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Title: Molecular evolution of animal aging.
Authors: Nussey DH; Institute of Ecology and Evolution, The University of Edinburgh School of Biological Sciences, Edinburgh, Edinburgh, UK., d'Adda di Fagagna F; IFOM ETS-The AIRC Institute of Molecular Oncology, Milan, Italy.; Institute of Molecular Genetics IGM-CNR 'Luigi Luca Cavalli-Sforza', Pavia, Italy., Bardin AJ; Institut Curie, PSL Research University, CNRS UMR 3215, INSERM U934, Stem Cells and Tissue Homeostasis Group, Paris, 75005, France., Blau HM; Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford School of Medicine, Stanford, CA, 94305-5175, USA., Brunet A; Glenn Laboratories for the Biology of Aging, Stanford University, Stanford, CA, USA., Bulavin DV; Institute for Research on Cancer and Aging of Nice (IRCAN); Université Côte d'Azur, INSERM; CNRS, Nice, France., Guo L; Department of Molecular Integrative Physiology, Department of Cell Developmental Biology, Institute of Gerontology, Geriatrics Center, University of Michigan, Ann Arbor, MI, USA., Hara E; Department of Molecular Microbiology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan., Junker JP; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin Institute for Medical Systems Biology, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Berlin, Germany.; German Center for Cardiovascular Research (DZHK), Site Berlin, Berlin, Germany., Gorbunova V; Department of Biology, University of Rochester, Rochester, NY, USA.; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA., Mittelbrunn M; Centro de Biología Molecular, Consejo Superior de Investigaciones Científicas, CSIC-UAM, Madrid, Spain., Rera M; Université Paris Cité, Biologie Fonctionnelle et Adaptative, Paris, France., Reznick J; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University Hospital Cologne, University of Cologne, Cologne, Germany., Seluanov A; Department of Biology, University of Rochester, Rochester, NY, USA.; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA., Schumacher B; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University Hospital Cologne, University of Cologne, Cologne, Germany.; Institute for Genome Stability in Aging and Disease, Medical Faculty, University and University Hospital of Cologne, Cologne, Germany.; Department of Biology, University of Crete, Heraklion, Crete, Greece., Teeling EC; School of Biology and Environmental Science, University College Dublin, Dublin, Ireland., Valenzano DR; Leibniz Institute on Aging, Fritz Lipmann Institute (FLI), Jena, Germany., Ye J; Department of Geriatrics, Medical Center on Aging of Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.; Pôle Sino-Français de Recherches en Sciences du Vivant Et Génomique, RuiJin Hospital, Shanghai Jiao Tong University School of Medicine, CNRS, Inserm, Université Côte d'Azur, Shanghai, China., Yun MH; Chinese Institutes for Medical Research, Beijing, China., Garinis GA; Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology-Hellas, Heraklion, Crete, Greece. garinis@imbb.forth.gr., Gilson E; Institute for Research on Cancer and Aging of Nice (IRCAN); Université Côte d'Azur, INSERM; CNRS, Nice, France. eric.gilson@univ-cotedazur.fr.; Pôle Sino-Français de Recherches en Sciences du Vivant Et Génomique, RuiJin Hospital, Shanghai Jiao Tong University School of Medicine, CNRS, Inserm, Université Côte d'Azur, Shanghai, China. eric.gilson@univ-cotedazur.fr.; Department of Medical Genetics, Institut Hospitalo-Universitaire (IHU) RESPIRera, CHU Nice, Nice, France. eric.gilson@univ-cotedazur.fr.
Source: The EMBO journal [EMBO J] 2026 Apr; Vol. 45 (7), pp. 2095-2111. Date of Electronic Publication: 2026 Feb 27.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Molecular evolution of animal aging.
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  Data: <searchLink fieldCode="AU" term="%22Nussey+DH%22">Nussey DH</searchLink>; Institute of Ecology and Evolution, The University of Edinburgh School of Biological Sciences, Edinburgh, Edinburgh, UK.<br /><searchLink fieldCode="AU" term="%22d'Adda+di+Fagagna+F%22">d'Adda di Fagagna F</searchLink>; IFOM ETS-The AIRC Institute of Molecular Oncology, Milan, Italy.; Institute of Molecular Genetics IGM-CNR 'Luigi Luca Cavalli-Sforza', Pavia, Italy.<br /><searchLink fieldCode="AU" term="%22Bardin+AJ%22">Bardin AJ</searchLink>; Institut Curie, PSL Research University, CNRS UMR 3215, INSERM U934, Stem Cells and Tissue Homeostasis Group, Paris, 75005, France.<br /><searchLink fieldCode="AU" term="%22Blau+HM%22">Blau HM</searchLink>; Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Stanford School of Medicine, Stanford, CA, 94305-5175, USA.<br /><searchLink fieldCode="AU" term="%22Brunet+A%22">Brunet A</searchLink>; Glenn Laboratories for the Biology of Aging, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Bulavin+DV%22">Bulavin DV</searchLink>; Institute for Research on Cancer and Aging of Nice (IRCAN); Université Côte d'Azur, INSERM; CNRS, Nice, France.<br /><searchLink fieldCode="AU" term="%22Guo+L%22">Guo L</searchLink>; Department of Molecular Integrative Physiology, Department of Cell Developmental Biology, Institute of Gerontology, Geriatrics Center, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Hara+E%22">Hara E</searchLink>; Department of Molecular Microbiology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.<br /><searchLink fieldCode="AU" term="%22Junker+JP%22">Junker JP</searchLink>; Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin Institute for Medical Systems Biology, Berlin, Germany.; Charité - Universitätsmedizin Berlin, Berlin, Germany.; German Center for Cardiovascular Research (DZHK), Site Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Gorbunova+V%22">Gorbunova V</searchLink>; Department of Biology, University of Rochester, Rochester, NY, USA.; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mittelbrunn+M%22">Mittelbrunn M</searchLink>; Centro de Biología Molecular, Consejo Superior de Investigaciones Científicas, CSIC-UAM, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Rera+M%22">Rera M</searchLink>; Université Paris Cité, Biologie Fonctionnelle et Adaptative, Paris, France.<br /><searchLink fieldCode="AU" term="%22Reznick+J%22">Reznick J</searchLink>; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University Hospital Cologne, University of Cologne, Cologne, Germany.<br /><searchLink fieldCode="AU" term="%22Seluanov+A%22">Seluanov A</searchLink>; Department of Biology, University of Rochester, Rochester, NY, USA.; Department of Medicine, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Schumacher+B%22">Schumacher B</searchLink>; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University Hospital Cologne, University of Cologne, Cologne, Germany.; Institute for Genome Stability in Aging and Disease, Medical Faculty, University and University Hospital of Cologne, Cologne, Germany.; Department of Biology, University of Crete, Heraklion, Crete, Greece.<br /><searchLink fieldCode="AU" term="%22Teeling+EC%22">Teeling EC</searchLink>; School of Biology and Environmental Science, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Valenzano+DR%22">Valenzano DR</searchLink>; Leibniz Institute on Aging, Fritz Lipmann Institute (FLI), Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Ye+J%22">Ye J</searchLink>; Department of Geriatrics, Medical Center on Aging of Shanghai Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.; Pôle Sino-Français de Recherches en Sciences du Vivant Et Génomique, RuiJin Hospital, Shanghai Jiao Tong University School of Medicine, CNRS, Inserm, Université Côte d'Azur, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yun+MH%22">Yun MH</searchLink>; Chinese Institutes for Medical Research, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Garinis+GA%22">Garinis GA</searchLink>; Institute of Molecular Biology and Biotechnology (IMBB), Foundation for Research and Technology-Hellas, Heraklion, Crete, Greece. garinis@imbb.forth.gr.<br /><searchLink fieldCode="AU" term="%22Gilson+E%22">Gilson E</searchLink>; Institute for Research on Cancer and Aging of Nice (IRCAN); Université Côte d'Azur, INSERM; CNRS, Nice, France. eric.gilson@univ-cotedazur.fr.; Pôle Sino-Français de Recherches en Sciences du Vivant Et Génomique, RuiJin Hospital, Shanghai Jiao Tong University School of Medicine, CNRS, Inserm, Université Côte d'Azur, Shanghai, China. eric.gilson@univ-cotedazur.fr.; Department of Medical Genetics, Institut Hospitalo-Universitaire (IHU) RESPIRera, CHU Nice, Nice, France. eric.gilson@univ-cotedazur.fr.
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