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Evaluating temozolomide for pediatric adamantinomatous craniopharyngiomas using microspheroid-based drug screening.

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Title: Evaluating temozolomide for pediatric adamantinomatous craniopharyngiomas using microspheroid-based drug screening.
Authors: Cavalheiro S; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.; National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology - INCT BioOncoPed, Porto Alegre, Brazil., Pavon LF; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.; National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology - INCT BioOncoPed, Porto Alegre, Brazil., de Farias CB; National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology - INCT BioOncoPed, Porto Alegre, Brazil.; Department of Translational Research, Ziel Biosciences, Porto Alegre, Rio Grande Do Sul, Brazil.; Postgraduate Program in Biological Sciences: Pharmacology and Therapeutics, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, RS, Brazil.; Postgraduate Program in Maternal and Child Health of the Institute of Pediatrics, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, RJ, Brazil., da Silva NS; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil., Nascimento FB; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil., Sibov TT; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil., Rodrigues JB; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil., Dastoli PA; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.; National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology - INCT BioOncoPed, Porto Alegre, Brazil., Suzuki FS; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil., Watanabe RA; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil., Kim IHT; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil., Lichtenfels M; Department of Translational Research, Ziel Biosciences, Porto Alegre, Rio Grande Do Sul, Brazil., da Silva CA; Department of Translational Research, Ziel Biosciences, Porto Alegre, Rio Grande Do Sul, Brazil., Cappellano A; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil., da Costa MDS; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil. marcoscostaneuro@gmail.com.; National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology - INCT BioOncoPed, Porto Alegre, Brazil. marcoscostaneuro@gmail.com.
Source: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery [Childs Nerv Syst] 2026 Feb 27; Vol. 42 (1). Date of Electronic Publication: 2026 Feb 27.
Publication Type: Journal Article; Case Reports
Journal Info: Publisher: Springer International Country of Publication: Germany NLM ID: 8503227 Publication Model: Electronic Cited Medium: Internet ISSN: 1433-0350 (Electronic) Linking ISSN: 02567040 NLM ISO Abbreviation: Childs Nerv Syst Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Evaluating temozolomide for pediatric adamantinomatous craniopharyngiomas using microspheroid-based drug screening.
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  Data: <searchLink fieldCode="AU" term="%22Cavalheiro+S%22">Cavalheiro S</searchLink>; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.; National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology - INCT BioOncoPed, Porto Alegre, Brazil.<br /><searchLink fieldCode="AU" term="%22Pavon+LF%22">Pavon LF</searchLink>; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.; National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology - INCT BioOncoPed, Porto Alegre, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Farias+CB%22">de Farias CB</searchLink>; National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology - INCT BioOncoPed, Porto Alegre, Brazil.; Department of Translational Research, Ziel Biosciences, Porto Alegre, Rio Grande Do Sul, Brazil.; Postgraduate Program in Biological Sciences: Pharmacology and Therapeutics, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, RS, Brazil.; Postgraduate Program in Maternal and Child Health of the Institute of Pediatrics, Universidade Federal Do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+NS%22">da Silva NS</searchLink>; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Nascimento+FB%22">Nascimento FB</searchLink>; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Sibov+TT%22">Sibov TT</searchLink>; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Rodrigues+JB%22">Rodrigues JB</searchLink>; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Dastoli+PA%22">Dastoli PA</searchLink>; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.; National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology - INCT BioOncoPed, Porto Alegre, Brazil.<br /><searchLink fieldCode="AU" term="%22Suzuki+FS%22">Suzuki FS</searchLink>; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Watanabe+RA%22">Watanabe RA</searchLink>; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Kim+IHT%22">Kim IHT</searchLink>; Translacional Neurosurgery Laboratory, Department of Neurology and Neurosurgery, Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Lichtenfels+M%22">Lichtenfels M</searchLink>; Department of Translational Research, Ziel Biosciences, Porto Alegre, Rio Grande Do Sul, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Silva+CA%22">da Silva CA</searchLink>; Department of Translational Research, Ziel Biosciences, Porto Alegre, Rio Grande Do Sul, Brazil.<br /><searchLink fieldCode="AU" term="%22Cappellano+A%22">Cappellano A</searchLink>; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22da+Costa+MDS%22">da Costa MDS</searchLink>; Pediatric Oncology Institute, Grupo de Apoio Ao Adolescente E À Criança Com Câncer (GRAACC), Universidade Federal de Sao Paulo (UNIFESP), São Paulo, SP, Brazil. marcoscostaneuro@gmail.com.; National Science and Technology Institute for Children's Cancer Biology and Pediatric Oncology - INCT BioOncoPed, Porto Alegre, Brazil. marcoscostaneuro@gmail.com.
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  Data: <searchLink fieldCode="JN" term="%228503227%22">Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery</searchLink> [Childs Nerv Syst] 2026 Feb 27; Vol. 42 (1). <i>Date of Electronic Publication: </i>2026 Feb 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+International%22">Springer International </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>8503227 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1433-0350 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202567040%22">02567040 </searchLink><i>NLM ISO Abbreviation: </i>Childs Nerv Syst <i>Subsets: </i>MEDLINE
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