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Pangenome-based design of strain-specific primers enables precise monitoring of bacteria in human microbiome intervention trials.

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Title: Pangenome-based design of strain-specific primers enables precise monitoring of bacteria in human microbiome intervention trials.
Authors: Eilers T; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium., Delanghe L; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium., De Boeck I; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium., Van Rillaer T; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium., Van Malderen J; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium., Bakelants S; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium., Van Beeck W; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium., Wittouck S; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium., Lebeer S; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium. sarah.lebeer@uantwerpen.be.
Source: Scientific reports [Sci Rep] 2026 Feb 27; Vol. 16 (1). Date of Electronic Publication: 2026 Feb 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pangenome-based design of strain-specific primers enables precise monitoring of bacteria in human microbiome intervention trials.
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  Data: <searchLink fieldCode="AU" term="%22Eilers+T%22">Eilers T</searchLink>; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium.<br /><searchLink fieldCode="AU" term="%22Delanghe+L%22">Delanghe L</searchLink>; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium.<br /><searchLink fieldCode="AU" term="%22De+Boeck+I%22">De Boeck I</searchLink>; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Rillaer+T%22">Van Rillaer T</searchLink>; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Malderen+J%22">Van Malderen J</searchLink>; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium.<br /><searchLink fieldCode="AU" term="%22Bakelants+S%22">Bakelants S</searchLink>; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Beeck+W%22">Van Beeck W</searchLink>; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium.<br /><searchLink fieldCode="AU" term="%22Wittouck+S%22">Wittouck S</searchLink>; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium.<br /><searchLink fieldCode="AU" term="%22Lebeer+S%22">Lebeer S</searchLink>; Department of Bioscience Engineering, Laboratory of Applied Microbiology and Biotechnology, University of Antwerp, Groenenborgerlaan 171, Antwerp, 2020, Belgium. sarah.lebeer@uantwerpen.be.
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  Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2026 Feb 27; Vol. 16 (1). <i>Date of Electronic Publication: </i>2026 Feb 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep <i>Subsets: </i>MEDLINE
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