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Hypomethylation of VTRNA2-1 promoter predicts adverse outcomes in peripheral artery disease.

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Title: Hypomethylation of VTRNA2-1 promoter predicts adverse outcomes in peripheral artery disease.
Authors: Tsai ML; Division of Cardiology, New Taipei Municipal TuCheng Hospital, New Taipei City, Taiwan.; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; College of Management, Chang Gung University, Taoyuan City, Taiwan., Huang YC; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Division of Cardiology, Linkou Medical Center, Chang Gung Memorial Hospital, 5 Fuxing Street, Guishan District, Taoyuan City, 33305, Taiwan., Ho MY; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Division of Cardiology, Linkou Medical Center, Chang Gung Memorial Hospital, 5 Fuxing Street, Guishan District, Taoyuan City, 33305, Taiwan., Yeh JK; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Division of Cardiology, Linkou Medical Center, Chang Gung Memorial Hospital, 5 Fuxing Street, Guishan District, Taoyuan City, 33305, Taiwan., Chen CC; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Division of Cardiology, Linkou Medical Center, Chang Gung Memorial Hospital, 5 Fuxing Street, Guishan District, Taoyuan City, 33305, Taiwan.; College of Life Sciences and Medicine, National Tsing Hua University, Hsinchu, Taiwan., Chia CY; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Division of Cardiology, Linkou Medical Center, Chang Gung Memorial Hospital, 5 Fuxing Street, Guishan District, Taoyuan City, 33305, Taiwan., Fan WL; Department of Medical Research, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan., Hsieh IC; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Division of Cardiology, Linkou Medical Center, Chang Gung Memorial Hospital, 5 Fuxing Street, Guishan District, Taoyuan City, 33305, Taiwan., Tsai CN; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan., Wang CY; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan. chaoyung@cgu.edu.tw.; Division of Cardiology, Linkou Medical Center, Chang Gung Memorial Hospital, 5 Fuxing Street, Guishan District, Taoyuan City, 33305, Taiwan. chaoyung@cgu.edu.tw.; Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan. chaoyung@cgu.edu.tw.; College of Life Sciences and Medicine, National Tsing Hua University, Hsinchu, Taiwan. chaoyung@cgu.edu.tw.
Source: Clinical epigenetics [Clin Epigenetics] 2026 Feb 27; Vol. 18 (1). Date of Electronic Publication: 2026 Feb 27.
Publication Type: Journal Article
Journal Info: Publisher: Biomed Central Country of Publication: Germany NLM ID: 101516977 Publication Model: Electronic Cited Medium: Internet ISSN: 1868-7083 (Electronic) Linking ISSN: 18687075 NLM ISO Abbreviation: Clin Epigenetics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Hypomethylation of VTRNA2-1 promoter predicts adverse outcomes in peripheral artery disease.
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  Data: <searchLink fieldCode="AU" term="%22Tsai+ML%22">Tsai ML</searchLink>; Division of Cardiology, New Taipei Municipal TuCheng Hospital, New Taipei City, Taiwan.; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; College of Management, Chang Gung University, Taoyuan City, Taiwan.<br /><searchLink fieldCode="AU" term="%22Huang+YC%22">Huang YC</searchLink>; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Division of Cardiology, Linkou Medical Center, Chang Gung Memorial Hospital, 5 Fuxing Street, Guishan District, Taoyuan City, 33305, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ho+MY%22">Ho MY</searchLink>; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Division of Cardiology, Linkou Medical Center, Chang Gung Memorial Hospital, 5 Fuxing Street, Guishan District, Taoyuan City, 33305, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+JK%22">Yeh JK</searchLink>; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Division of Cardiology, Linkou Medical Center, Chang Gung Memorial Hospital, 5 Fuxing Street, Guishan District, Taoyuan City, 33305, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+CC%22">Chen CC</searchLink>; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Division of Cardiology, Linkou Medical Center, Chang Gung Memorial Hospital, 5 Fuxing Street, Guishan District, Taoyuan City, 33305, Taiwan.; College of Life Sciences and Medicine, National Tsing Hua University, Hsinchu, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chia+CY%22">Chia CY</searchLink>; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Division of Cardiology, Linkou Medical Center, Chang Gung Memorial Hospital, 5 Fuxing Street, Guishan District, Taoyuan City, 33305, Taiwan.<br /><searchLink fieldCode="AU" term="%22Fan+WL%22">Fan WL</searchLink>; Department of Medical Research, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Hsieh+IC%22">Hsieh IC</searchLink>; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Division of Cardiology, Linkou Medical Center, Chang Gung Memorial Hospital, 5 Fuxing Street, Guishan District, Taoyuan City, 33305, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+CN%22">Tsai CN</searchLink>; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan.; Graduate Institute of Clinical Medical Sciences, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wang+CY%22">Wang CY</searchLink>; School of Medicine, College of Medicine, Chang Gung University, Taoyuan City, Taiwan. chaoyung@cgu.edu.tw.; Division of Cardiology, Linkou Medical Center, Chang Gung Memorial Hospital, 5 Fuxing Street, Guishan District, Taoyuan City, 33305, Taiwan. chaoyung@cgu.edu.tw.; Institute of Cellular and System Medicine, National Health Research Institutes, Zhunan, Taiwan. chaoyung@cgu.edu.tw.; College of Life Sciences and Medicine, National Tsing Hua University, Hsinchu, Taiwan. chaoyung@cgu.edu.tw.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Biomed+Central%22">Biomed Central </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>101516977 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1868-7083 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218687075%22">18687075 </searchLink><i>NLM ISO Abbreviation: </i>Clin Epigenetics <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s13148-026-02087-z
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      – Code: eng
        Text: English
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      – TitleFull: Hypomethylation of VTRNA2-1 promoter predicts adverse outcomes in peripheral artery disease.
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              Text: 2026 Feb 27
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              Y: 2026
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