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HSPA6 is induced by RIG-I-like receptors and negatively regulates type-I interferon signaling.

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Title: HSPA6 is induced by RIG-I-like receptors and negatively regulates type-I interferon signaling.
Authors: Liu Y; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China., Zhao Z; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, China., Ji X; Haihe Laboratory of Cell Ecosystem, Tianjin, 300457, China., Lei Y; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China., Zheng D; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China., Huang Y; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China., An J; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China., Gao C; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China., Wang Z; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China., Si Y; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China., Chen X; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China., Li X; Jinnan Hospital, Tianjin University, (Tianjin Jinnan Hospital), Tianjin, 300350, China., Peng S; Jinnan Hospital, Tianjin University, (Tianjin Jinnan Hospital), Tianjin, 300350, China.; Medical School, Tianjin University, Tianjin, 300072, China., Yu H; Jinnan Hospital, Tianjin University, (Tianjin Jinnan Hospital), Tianjin, 300350, China. yuhongjian84@163.com., Liu Z; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China. zichuan.liu@tju.edu.cn.; Jinnan Hospital, Tianjin University, (Tianjin Jinnan Hospital), Tianjin, 300350, China. zichuan.liu@tju.edu.cn.; State Key Laboratory of Synthetic Biology, Tianjin University, Tianjin, 300072, China. zichuan.liu@tju.edu.cn.; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, 300072, China. zichuan.liu@tju.edu.cn., Zhu Z; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, China. zhuzixiang@caas.cn., Mu X; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China. xin_mu@tju.edu.cn.; Jinnan Hospital, Tianjin University, (Tianjin Jinnan Hospital), Tianjin, 300350, China. xin_mu@tju.edu.cn.
Source: Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2026 Feb 28; Vol. 83 (1). Date of Electronic Publication: 2026 Feb 28.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Switzerland NLM ID: 9705402 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-9071 (Electronic) Linking ISSN: 1420682X NLM ISO Abbreviation: Cell Mol Life Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: HSPA6 is induced by RIG-I-like receptors and negatively regulates type-I interferon signaling.
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  Data: <searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China.<br /><searchLink fieldCode="AU" term="%22Zhao+Z%22">Zhao Z</searchLink>; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, China.<br /><searchLink fieldCode="AU" term="%22Ji+X%22">Ji X</searchLink>; Haihe Laboratory of Cell Ecosystem, Tianjin, 300457, China.<br /><searchLink fieldCode="AU" term="%22Lei+Y%22">Lei Y</searchLink>; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China.<br /><searchLink fieldCode="AU" term="%22Zheng+D%22">Zheng D</searchLink>; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China.<br /><searchLink fieldCode="AU" term="%22An+J%22">An J</searchLink>; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China.<br /><searchLink fieldCode="AU" term="%22Gao+C%22">Gao C</searchLink>; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China.<br /><searchLink fieldCode="AU" term="%22Si+Y%22">Si Y</searchLink>; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Jinnan Hospital, Tianjin University, (Tianjin Jinnan Hospital), Tianjin, 300350, China.<br /><searchLink fieldCode="AU" term="%22Peng+S%22">Peng S</searchLink>; Jinnan Hospital, Tianjin University, (Tianjin Jinnan Hospital), Tianjin, 300350, China.; Medical School, Tianjin University, Tianjin, 300072, China.<br /><searchLink fieldCode="AU" term="%22Yu+H%22">Yu H</searchLink>; Jinnan Hospital, Tianjin University, (Tianjin Jinnan Hospital), Tianjin, 300350, China. yuhongjian84@163.com.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China. zichuan.liu@tju.edu.cn.; Jinnan Hospital, Tianjin University, (Tianjin Jinnan Hospital), Tianjin, 300350, China. zichuan.liu@tju.edu.cn.; State Key Laboratory of Synthetic Biology, Tianjin University, Tianjin, 300072, China. zichuan.liu@tju.edu.cn.; Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), Tianjin University, Tianjin, 300072, China. zichuan.liu@tju.edu.cn.<br /><searchLink fieldCode="AU" term="%22Zhu+Z%22">Zhu Z</searchLink>; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730046, China. zhuzixiang@caas.cn.<br /><searchLink fieldCode="AU" term="%22Mu+X%22">Mu X</searchLink>; Tianjin University and Health-Biotech United Group Joint Laboratory of Innovative Drug Development and Translational Medicine, School of Pharmaceutical Science and Technology, Faculty of Medicine, Tianjin University, Tianjin, 300072, China. xin_mu@tju.edu.cn.; Jinnan Hospital, Tianjin University, (Tianjin Jinnan Hospital), Tianjin, 300350, China. xin_mu@tju.edu.cn.
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        Value: 10.1007/s00018-026-06147-8
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