Constitutive neuronal expression and disease-associated upregulation of chitinases in amyotrophic lateral sclerosis.

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Title: Constitutive neuronal expression and disease-associated upregulation of chitinases in amyotrophic lateral sclerosis.
Authors: Gaur N; Hans Berger Department of Neurology, Friedrich Schiller University Hospital Jena, Jena 07740, Germany., Angerer C; Institute of Neuronal Cell Biology, School of Medicine and Health, Technical University of Munich, Munich 80802, Germany., Gunes ZI; Institute of Clinical Neuroimmunology, Klinikum der Universität München, Ludwig-Maximilians University Munich, Martinsried 82152, Germany.; Centre for Neuropathology and Prion Research, Ludwig-Maximilians-University Munich, Munich 81377, Germany., Ancau M; Institute of Neuronal Cell Biology, School of Medicine and Health, Technical University of Munich, Munich 80802, Germany.; Department of Neurology, Klinikum Rechts der Isar, School of Medicine and Health, Technical University of Munich, Munich 81675, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich 81377, Germany., Wang M; Institute of Neuronal Cell Biology, School of Medicine and Health, Technical University of Munich, Munich 80802, Germany., Riemenschneider H; Munich Cluster for Systems Neurology (SyNergy), Munich 81377, Germany.; German Centre for Neurodegenerative Diseases (DZNE), Munich 81377, Germany., Hurler CA; Institute for Stroke and Dementia Research, University Hospital, Ludwig-Maximilians-University, Munich 81377, Germany., Mungwa S; Institute of Clinical Neurobiology, University Hospital Wuerzburg, Wuerzburg 97078, Germany., Lüningschrör P; Institute of Clinical Neurobiology, University Hospital Wuerzburg, Wuerzburg 97078, Germany., Zhiti A; Institute of Neuronal Cell Biology, School of Medicine and Health, Technical University of Munich, Munich 80802, Germany., Steinbach R; Institute of Biomedicine and Translational Medicine, Laboratory Animal Centre, University of Tartu, Tartu 50411, Estonia., Briese M; Institute of Clinical Neurobiology, University Hospital Wuerzburg, Wuerzburg 97078, Germany., Srivastava M; Core Unit Systems Medicine, University of Wuerzburg, Wuerzburg 97078, Germany., Plaas M; Institute of Biomedicine and Translational Medicine, Laboratory Animal Centre, University of Tartu, Tartu 50411, Estonia., Hermann A; Translational Neurodegeneration Section 'Albrecht Kossel', Department of Neurology, University Medical Center Rostock, Rostock 18147, Germany.; German Center for Neurodegenerative Diseases (DZNE), Greifswald 17489 and Rostock 18147, Germany., Sendtner M; Institute of Clinical Neurobiology, University Hospital Wuerzburg, Wuerzburg 97078, Germany., Jäkel S; Munich Cluster for Systems Neurology (SyNergy), Munich 81377, Germany.; Institute for Stroke and Dementia Research, University Hospital, Ludwig-Maximilians-University, Munich 81377, Germany., Edbauer D; Munich Cluster for Systems Neurology (SyNergy), Munich 81377, Germany.; German Centre for Neurodegenerative Diseases (DZNE), Munich 81377, Germany., Herms J; Centre for Neuropathology and Prion Research, Ludwig-Maximilians-University Munich, Munich 81377, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich 81377, Germany.; German Centre for Neurodegenerative Diseases (DZNE), Munich 81377, Germany., Liebscher S; Institute of Clinical Neuroimmunology, Klinikum der Universität München, Ludwig-Maximilians University Munich, Martinsried 82152, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich 81377, Germany.; Department of Psychiatry and Psychotherapy, University Hospital, Ludwig-Maximilians-University, Munich 80336, Germany.; Biomedical Center, Ludwig-Maximilians University Munich, Martinsried 82152, Germany.; Institute of Systems Neuroscience, Medical University of Innsbruck, Innsbruck 6020, Austria., Grosskreutz J; Institute of Clinical Neurobiology, University Hospital Wuerzburg, Wuerzburg 97078, Germany.; Cluster for Precision Medicine in Inflammation, Universities of Kiel and Lübeck, Kiel 24118, Germany.; Precision Neurology of Neuromuscular and Motor Neuron Diseases, University of Lübeck, Lübeck 23538, Germany., Brill MS; Institute of Neuronal Cell Biology, School of Medicine and Health, Technical University of Munich, Munich 80802, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich 81377, Germany.
Source: Brain : a journal of neurology [Brain] 2026 Feb 28. Date of Electronic Publication: 2026 Feb 28.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1460-2156
DOI:10.1093/brain/awag083