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Obesity and breast density enhance immune exclusion in the primary tumor microenvironment and promote breast cancer metastasis.

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Title: Obesity and breast density enhance immune exclusion in the primary tumor microenvironment and promote breast cancer metastasis.
Authors: Williams AE; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA., Hoffmann EJ; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Inman DR; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Gari MK; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Zhou C; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Burkel BM; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Haidar N; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Pan Y; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA., Halambeck M; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA., Moore BN; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA., Wisinski KB; Department of Medicine, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.; University of Wisconsin-Carbone Cancer Center, Madison, WI, USA., McGregor SM; University of Wisconsin-Carbone Cancer Center, Madison, WI, USA.; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, USA., Kerr SC; University of Wisconsin-Carbone Cancer Center, Madison, WI, USA., Arendt LM; Department of Comparative Biosciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.; University of Wisconsin-Carbone Cancer Center, Madison, WI, USA., Ponik SM; Department of Cell and Regenerative Biology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA. ponik@wisc.edu.; University of Wisconsin-Carbone Cancer Center, Madison, WI, USA. ponik@wisc.edu.
Source: Oncogene [Oncogene] 2026 Mar; Vol. 45 (11), pp. 1057-1064. Date of Electronic Publication: 2026 Feb 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE
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  Data: <searchLink fieldCode="JN" term="%228711562%22">Oncogene</searchLink> [Oncogene] 2026 Mar; Vol. 45 (11), pp. 1057-1064. <i>Date of Electronic Publication: </i>2026 Feb 28.
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