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Multi-ancestry genome-wide association study and meta-analysis of lung function decline.

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Title: Multi-ancestry genome-wide association study and meta-analysis of lung function decline.
Authors: Patchen BK; Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Zhang J; Boston University School of Public Health, Boston, MA, USA., Gaddis N; RTI International, Research Triangle Park, NC, USA., Bartz TM; Cardiovascular Health Research Unit, Departments of Biostatistics and Medicine, University of Washington, Seattle, WA, USA., Chen J; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK., Debban C; Department of Genome Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA., Leonard H; Laboratory of Neurogenetics, National Institute of Aging, National Institute of Health, Bethesda, MD, USA., Nguyen NQH; School of Public Health, University of Texas Health Science Center, Houston, TX, USA., Seo J; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.; Department of MetaBioHealth, Sungkyunkwan University (SKKU), Suwon, Republic of Korea., Tern C; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Allen R; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK., DeMeo DL; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Fornage M; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center, Houston, TX, USA., Melbourne C; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK.; UK Biobank, Ltd, Stockport, UK., Minto M; RTI International, Research Triangle Park, NC, USA., Moll M; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., O'Connor GT; Boston University School of Medicine, Boston, MA, USA., Pottinger T; Institute for Genomic Medicine, Columbia University Irving Medical Center, New York, NY, USA., Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology, Health Systems and Population Health, University of Washington, Seattle, WA, USA., Rich SS; Department of Genome Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Silverman EK; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Stratford J; RTI International, Research Triangle Park, NC, USA., Zhang C; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Barr RG; Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA., Cho MH; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Gharib SA; Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, WA, USA., Manichaikul A; Department of Genome Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA., North K; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Oelsner EC; Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA., Simonsick EM; Intramural Research Program, National Institute on Aging, Baltimore, MD, USA., Tobin MD; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK., Yu B; School of Public Health, University of Texas Health Science Center, Houston, TX, USA., Choi SH; Boston University School of Public Health, Boston, MA, USA., Dupuis J; Boston University School of Public Health, Boston, MA, USA.; Department of Epidemiology, Biostatistics and Occupational Health, School of Population and Global Health, McGill University, Montréal, Québec, Canada., Cassano PA; Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.; Department of Population Health Sciences, Division of Epidemiology, Weill Cornell Medicine, New York, NY, USA., Hancock DB; RTI International, Research Triangle Park, NC, USA. dhancock@rti.org.
Source: Respiratory research [Respir Res] 2026 Feb 28; Vol. 27 (1). Date of Electronic Publication: 2026 Feb 28.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 101090633 Publication Model: Electronic Cited Medium: Internet ISSN: 1465-993X (Electronic) Linking ISSN: 14659921 NLM ISO Abbreviation: Respir Res Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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  Data: <searchLink fieldCode="AU" term="%22Patchen+BK%22">Patchen BK</searchLink>; Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gaddis+N%22">Gaddis N</searchLink>; RTI International, Research Triangle Park, NC, USA.<br /><searchLink fieldCode="AU" term="%22Bartz+TM%22">Bartz TM</searchLink>; Cardiovascular Health Research Unit, Departments of Biostatistics and Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Debban+C%22">Debban C</searchLink>; Department of Genome Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Leonard+H%22">Leonard H</searchLink>; Laboratory of Neurogenetics, National Institute of Aging, National Institute of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Nguyen+NQH%22">Nguyen NQH</searchLink>; School of Public Health, University of Texas Health Science Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Seo+J%22">Seo J</searchLink>; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.; Department of MetaBioHealth, Sungkyunkwan University (SKKU), Suwon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Tern+C%22">Tern C</searchLink>; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Allen+R%22">Allen R</searchLink>; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22DeMeo+DL%22">DeMeo DL</searchLink>; 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RTI International, Research Triangle Park, NC, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Barr+RG%22">Barr RG</searchLink>; Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Cho+MH%22">Cho MH</searchLink>; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Gharib+SA%22">Gharib SA</searchLink>; Division of Pulmonary, Critical Care and Sleep Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Manichaikul+A%22">Manichaikul A</searchLink>; Department of Genome Sciences, University of Virginia School of Medicine, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22North+K%22">North K</searchLink>; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Oelsner+EC%22">Oelsner EC</searchLink>; Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Simonsick+EM%22">Simonsick EM</searchLink>; Intramural Research Program, National Institute on Aging, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Tobin+MD%22">Tobin MD</searchLink>; Division of Public Health and Epidemiology, School of Medical Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Yu+B%22">Yu B</searchLink>; School of Public Health, University of Texas Health Science Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Choi+SH%22">Choi SH</searchLink>; Boston University School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Dupuis+J%22">Dupuis J</searchLink>; Boston University School of Public Health, Boston, MA, USA.; Department of Epidemiology, Biostatistics and Occupational Health, School of Population and Global Health, McGill University, Montréal, Québec, Canada.<br /><searchLink fieldCode="AU" term="%22Cassano+PA%22">Cassano PA</searchLink>; Division of Nutritional Sciences, Cornell University, Ithaca, NY, USA.; Department of Population Health Sciences, Division of Epidemiology, Weill Cornell Medicine, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Hancock+DB%22">Hancock DB</searchLink>; RTI International, Research Triangle Park, NC, USA. dhancock@rti.org.
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