A novel Chinese medicine formula against hyperuricemia-induced kidney inflammation involving pyroptosis inhibition via modulating AMPK-TLR4-NLRP3 pathway.

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Title: A novel Chinese medicine formula against hyperuricemia-induced kidney inflammation involving pyroptosis inhibition via modulating AMPK-TLR4-NLRP3 pathway.
Authors: Tian YY; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, 999077, China., Wu YL; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, 999077, China., Lam KK; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, 999077, China., Zhu H; Department of Oncology, Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China., Xian YF; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, 999077, China. lisaxian@cuhk.edu.hk.; The Chinese University of Hong Kong Chinese Medicine Specialty Clinic Cum Clinical Teaching and Research Centre, School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China. lisaxian@cuhk.edu.hk., Lin ZX; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, 999077, China. linzx@cuhk.edu.hk.; The Chinese University of Hong Kong Chinese Medicine Specialty Clinic Cum Clinical Teaching and Research Centre, School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China. linzx@cuhk.edu.hk.; Hong Kong Institute of Integrative Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China. linzx@cuhk.edu.hk.
Source: Chinese medicine [Chin Med] 2026 Mar 01; Vol. 21 (1). Date of Electronic Publication: 2026 Mar 01.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101265109 Publication Model: Electronic Cited Medium: Print ISSN: 1749-8546 (Print) Linking ISSN: 17498546 NLM ISO Abbreviation: Chin Med Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: A novel Chinese medicine formula against hyperuricemia-induced kidney inflammation involving pyroptosis inhibition via modulating AMPK-TLR4-NLRP3 pathway.
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  Data: <searchLink fieldCode="AU" term="%22Tian+YY%22">Tian YY</searchLink>; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, 999077, China.<br /><searchLink fieldCode="AU" term="%22Wu+YL%22">Wu YL</searchLink>; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, 999077, China.<br /><searchLink fieldCode="AU" term="%22Lam+KK%22">Lam KK</searchLink>; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, 999077, China.<br /><searchLink fieldCode="AU" term="%22Zhu+H%22">Zhu H</searchLink>; Department of Oncology, Wuxi Affiliated Hospital of Nanjing University of Chinese Medicine, Wuxi, China.<br /><searchLink fieldCode="AU" term="%22Xian+YF%22">Xian YF</searchLink>; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, 999077, China. lisaxian@cuhk.edu.hk.; The Chinese University of Hong Kong Chinese Medicine Specialty Clinic Cum Clinical Teaching and Research Centre, School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China. lisaxian@cuhk.edu.hk.<br /><searchLink fieldCode="AU" term="%22Lin+ZX%22">Lin ZX</searchLink>; School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong SAR, 999077, China. linzx@cuhk.edu.hk.; The Chinese University of Hong Kong Chinese Medicine Specialty Clinic Cum Clinical Teaching and Research Centre, School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China. linzx@cuhk.edu.hk.; Hong Kong Institute of Integrative Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China. linzx@cuhk.edu.hk.
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        Value: 10.1186/s13020-025-01271-2
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        Text: English
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      – TitleFull: A novel Chinese medicine formula against hyperuricemia-induced kidney inflammation involving pyroptosis inhibition via modulating AMPK-TLR4-NLRP3 pathway.
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              Text: 2026 Mar 01
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