Sepsis.

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Title: Sepsis.
Authors: Singer M; Bloomsbury Intensive Care Medicine Institute, Centre for Respiratory Medicine, University College London, London, UK. Electronic address: m.singer@ucl.ac.uk., Angus DC; Center for Clinical Research, Investigation, and Systems Modeling of Acute Illness, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Annane D; IHU PROMETHEUS, Comprehensive Sepsis Centre, General Intensive Care Unit, Raymond Poincaré Hospital, Garches, France; School of Medicine Simone Veil, University of Versailles Saint-Quentin-en-Yvelines, Paris, France., Bauer M; Department of Anaesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany., Kalil AC; Division of Infectious Diseases, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA., Klompas M; Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Healthcare Institute, Boston, MA, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA., Machado FR; Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil., Martin GS; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University, Atlanta, GA, USA; Grady Memorial Hospital, Atlanta, GA, USA., Randolph AG; Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, MA, USA; Department of Anesthesiology, and Department of Pediatrics, Harvard Medical School, Boston, MA, USA., Shankar-Hari M; Centre for Critical Illness Research, King's College London, London, UK., Shapiro NI; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Van den Berghe G; Clinical Division, and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
Source: Lancet (London, England) [Lancet] 2026 Mar 28; Vol. 407 (10535), pp. 1276-1288. Date of Electronic Publication: 2026 Feb 26.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 2985213R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-547X (Electronic) Linking ISSN: 01406736 NLM ISO Abbreviation: Lancet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Sepsis.
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  Data: <searchLink fieldCode="AU" term="%22Singer+M%22">Singer M</searchLink>; Bloomsbury Intensive Care Medicine Institute, Centre for Respiratory Medicine, University College London, London, UK. Electronic address: m.singer@ucl.ac.uk.<br /><searchLink fieldCode="AU" term="%22Angus+DC%22">Angus DC</searchLink>; Center for Clinical Research, Investigation, and Systems Modeling of Acute Illness, Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Annane+D%22">Annane D</searchLink>; IHU PROMETHEUS, Comprehensive Sepsis Centre, General Intensive Care Unit, Raymond Poincaré Hospital, Garches, France; School of Medicine Simone Veil, University of Versailles Saint-Quentin-en-Yvelines, Paris, France.<br /><searchLink fieldCode="AU" term="%22Bauer+M%22">Bauer M</searchLink>; Department of Anaesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Kalil+AC%22">Kalil AC</searchLink>; Division of Infectious Diseases, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Klompas+M%22">Klompas M</searchLink>; Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Healthcare Institute, Boston, MA, USA; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Machado+FR%22">Machado FR</searchLink>; Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Martin+GS%22">Martin GS</searchLink>; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University, Atlanta, GA, USA; Grady Memorial Hospital, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Randolph+AG%22">Randolph AG</searchLink>; Department of Anesthesiology, Critical Care, and Pain Medicine, Boston Children's Hospital, Boston, MA, USA; Department of Anesthesiology, and Department of Pediatrics, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Shankar-Hari+M%22">Shankar-Hari M</searchLink>; Centre for Critical Illness Research, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Shapiro+NI%22">Shapiro NI</searchLink>; Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Van+den+Berghe+G%22">Van den Berghe G</searchLink>; Clinical Division, and Laboratory of Intensive Care Medicine, Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.
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  Data: <searchLink fieldCode="JN" term="%222985213R%22">Lancet (London, England)</searchLink> [Lancet] 2026 Mar 28; Vol. 407 (10535), pp. 1276-1288. <i>Date of Electronic Publication: </i>2026 Feb 26.
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              Text: 2026 Mar 28
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