Aetiology of sepsis in adults living with HIV in East Africa: a secondary analysis of an open-label, multicentre, randomised, controlled phase 3 trial.

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Title: Aetiology of sepsis in adults living with HIV in East Africa: a secondary analysis of an open-label, multicentre, randomised, controlled phase 3 trial.
Authors: Otoupalova E; Division of Pulmonary, Critical Care, and Environmental Medicine, Department of Medicine, Tulane University School of Medicine, New Orleans, USA., Ampaire L; Department of Medical Laboratory Sciences, Mbarara University School of Science and Technology Faculty of Medicine, Mbarara, Uganda., Null M; Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, USA., Mujaga B; Biotechnology Laboratory, Kilimanjaro Clinical Research Institute, Moshi, Tanzania., Liu J; Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, USA., Said B; Department of Medicine, Kibong'oto Infectious Disease Hospital, Sanya Juu, Tanzania., Nuwagira E; Department of Medicine, Mbarara University School of Science and Technology Faculty of Medicine, Mbarara, Uganda., Sariko M; Biotechnology Laboratory, Kilimanjaro Clinical Research Institute, Moshi, Tanzania., Gidoi G; Department of Medicine, Mbarara University School of Science and Technology Faculty of Medicine, Mbarara, Uganda., Gulinja A; Department of Medicine, Kibong'oto Infectious Disease Hospital, Sanya Juu, Tanzania., Jjunju S; Department of Medicine, Mbarara University School of Science and Technology Faculty of Medicine, Mbarara, Uganda., Rimoy A; Department of Medicine, Kibong'oto Infectious Disease Hospital, Sanya Juu, Tanzania., Mwita FC; Mwanza Research Centre, National Institute for Medical Research, Mwanza, Tanzania., Kidola J; Mwanza Research Centre, National Institute for Medical Research, Mwanza, Tanzania., Atwiine O; Fort Portal Regional Referral Hospital, Fort Portal, Uganda., Ocaaki D; Fort Portal Regional Referral Hospital, Fort Portal, Uganda., Munyambalu DK; Fort Portal Regional Referral Hospital, Fort Portal, Uganda., Rao P; Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, USA., Boulware DR; Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, USA., Thomas TA; Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, USA., Mpagama S; Department of Medicine, Kibong'oto Infectious Disease Hospital, Sanya Juu, Tanzania., Muzoora C; Department of Medicine, Mbarara University School of Science and Technology Faculty of Medicine, Mbarara, Uganda., Heysell SK; Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, USA., Moore CC; Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, USA.; Department of Medicine, Mbarara University School of Science and Technology Faculty of Medicine, Mbarara, Uganda.
Source: EClinicalMedicine [EClinicalMedicine] 2026 Jan 28; Vol. 92, pp. 103719. Date of Electronic Publication: 2026 Jan 28 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: The Lancet Country of Publication: England NLM ID: 101733727 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-5370 (Electronic) Linking ISSN: 25895370 NLM ISO Abbreviation: EClinicalMedicine Subsets: PubMed not MEDLINE
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  Data: Aetiology of sepsis in adults living with HIV in East Africa: a secondary analysis of an open-label, multicentre, randomised, controlled phase 3 trial.
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  Data: <searchLink fieldCode="AU" term="%22Otoupalova+E%22">Otoupalova E</searchLink>; Division of Pulmonary, Critical Care, and Environmental Medicine, Department of Medicine, Tulane University School of Medicine, New Orleans, USA.<br /><searchLink fieldCode="AU" term="%22Ampaire+L%22">Ampaire L</searchLink>; Department of Medical Laboratory Sciences, Mbarara University School of Science and Technology Faculty of Medicine, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Null+M%22">Null M</searchLink>; Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, USA.<br /><searchLink fieldCode="AU" term="%22Mujaga+B%22">Mujaga B</searchLink>; Biotechnology Laboratory, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, USA.<br /><searchLink fieldCode="AU" term="%22Said+B%22">Said B</searchLink>; Department of Medicine, Kibong'oto Infectious Disease Hospital, Sanya Juu, Tanzania.<br /><searchLink fieldCode="AU" term="%22Nuwagira+E%22">Nuwagira E</searchLink>; Department of Medicine, Mbarara University School of Science and Technology Faculty of Medicine, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Sariko+M%22">Sariko M</searchLink>; Biotechnology Laboratory, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.<br /><searchLink fieldCode="AU" term="%22Gidoi+G%22">Gidoi G</searchLink>; Department of Medicine, Mbarara University School of Science and Technology Faculty of Medicine, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Gulinja+A%22">Gulinja A</searchLink>; Department of Medicine, Kibong'oto Infectious Disease Hospital, Sanya Juu, Tanzania.<br /><searchLink fieldCode="AU" term="%22Jjunju+S%22">Jjunju S</searchLink>; Department of Medicine, Mbarara University School of Science and Technology Faculty of Medicine, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Rimoy+A%22">Rimoy A</searchLink>; Department of Medicine, Kibong'oto Infectious Disease Hospital, Sanya Juu, Tanzania.<br /><searchLink fieldCode="AU" term="%22Mwita+FC%22">Mwita FC</searchLink>; Mwanza Research Centre, National Institute for Medical Research, Mwanza, Tanzania.<br /><searchLink fieldCode="AU" term="%22Kidola+J%22">Kidola J</searchLink>; Mwanza Research Centre, National Institute for Medical Research, Mwanza, Tanzania.<br /><searchLink fieldCode="AU" term="%22Atwiine+O%22">Atwiine O</searchLink>; Fort Portal Regional Referral Hospital, Fort Portal, Uganda.<br /><searchLink fieldCode="AU" term="%22Ocaaki+D%22">Ocaaki D</searchLink>; Fort Portal Regional Referral Hospital, Fort Portal, Uganda.<br /><searchLink fieldCode="AU" term="%22Munyambalu+DK%22">Munyambalu DK</searchLink>; Fort Portal Regional Referral Hospital, Fort Portal, Uganda.<br /><searchLink fieldCode="AU" term="%22Rao+P%22">Rao P</searchLink>; Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, USA.<br /><searchLink fieldCode="AU" term="%22Boulware+DR%22">Boulware DR</searchLink>; Division of Infectious Diseases and International Medicine, Department of Medicine, University of Minnesota, Minneapolis, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+TA%22">Thomas TA</searchLink>; Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, USA.<br /><searchLink fieldCode="AU" term="%22Mpagama+S%22">Mpagama S</searchLink>; Department of Medicine, Kibong'oto Infectious Disease Hospital, Sanya Juu, Tanzania.<br /><searchLink fieldCode="AU" term="%22Muzoora+C%22">Muzoora C</searchLink>; Department of Medicine, Mbarara University School of Science and Technology Faculty of Medicine, Mbarara, Uganda.<br /><searchLink fieldCode="AU" term="%22Heysell+SK%22">Heysell SK</searchLink>; Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, USA.<br /><searchLink fieldCode="AU" term="%22Moore+CC%22">Moore CC</searchLink>; Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, USA.; Department of Medicine, Mbarara University School of Science and Technology Faculty of Medicine, Mbarara, Uganda.
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  Data: <searchLink fieldCode="JN" term="%22101733727%22">EClinicalMedicine</searchLink> [EClinicalMedicine] 2026 Jan 28; Vol. 92, pp. 103719. <i>Date of Electronic Publication: </i>2026 Jan 28 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22The+Lancet%22">The Lancet </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101733727 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2589-5370 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225895370%22">25895370 </searchLink><i>NLM ISO Abbreviation: </i>EClinicalMedicine <i>Subsets: </i>PubMed not MEDLINE
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