View in EDS HTML Full Text PDF Full Text

Cheminformatics-driven discovery of natural isoquinoline alkaloid inhibitors of Beta-secretase I for Alzheimer's management.

Saved in:
Bibliographic Details
Title: Cheminformatics-driven discovery of natural isoquinoline alkaloid inhibitors of Beta-secretase I for Alzheimer's management.
Authors: Ahmad I; Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan., Waheed S; Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan., Alotaibi BS; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Al- Quwayiyah, Shaqra University, Riyadh, Saudi Arabia., Abbasi SW; Department of Biological Sciences, National University of Medical Sciences, Rawalpindi, Pakistan., Khan MU; Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan., Rahman FU; Department of Zoology, University of Shangla, Swat, Khyber Pakhtunkhwa, Pakistan., Dib H; College of Engineering and Technology, American University of the Middle East, Kuwait., Fawy KF; Department of Chemistry, Faculty of Science, Research Center for Advanced Materials Science (RCAMS), King Khalid University, Abha, Saudi Arabia., Nishan U; Department of Chemistry, Kohat University of Science & Technology, Kohat, Pakistan., Ali A; Department of Zoology, Abdul Wali Khan University Mardan, Mardan, Pakistan., Zaman A; Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.; Department of Microbiology & Molecular Genetics, Bahauddin Zakariya University, Multan, Pakistan., Shah M; Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.; Department of Animal Science, Federal University of Ceara, Fortaleza, Brazil.
Source: PloS one [PLoS One] 2026 Mar 02; Vol. 21 (3), pp. e0343717. Date of Electronic Publication: 2026 Mar 02 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41770783
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Cheminformatics-driven discovery of natural isoquinoline alkaloid inhibitors of Beta-secretase I for Alzheimer's management.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Ahmad+I%22">Ahmad I</searchLink>; Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.<br /><searchLink fieldCode="AU" term="%22Waheed+S%22">Waheed S</searchLink>; Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.<br /><searchLink fieldCode="AU" term="%22Alotaibi+BS%22">Alotaibi BS</searchLink>; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Al- Quwayiyah, Shaqra University, Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Abbasi+SW%22">Abbasi SW</searchLink>; Department of Biological Sciences, National University of Medical Sciences, Rawalpindi, Pakistan.<br /><searchLink fieldCode="AU" term="%22Khan+MU%22">Khan MU</searchLink>; Institute of Molecular Biology and Biotechnology, The University of Lahore, Lahore, Pakistan.<br /><searchLink fieldCode="AU" term="%22Rahman+FU%22">Rahman FU</searchLink>; Department of Zoology, University of Shangla, Swat, Khyber Pakhtunkhwa, Pakistan.<br /><searchLink fieldCode="AU" term="%22Dib+H%22">Dib H</searchLink>; College of Engineering and Technology, American University of the Middle East, Kuwait.<br /><searchLink fieldCode="AU" term="%22Fawy+KF%22">Fawy KF</searchLink>; Department of Chemistry, Faculty of Science, Research Center for Advanced Materials Science (RCAMS), King Khalid University, Abha, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Nishan+U%22">Nishan U</searchLink>; Department of Chemistry, Kohat University of Science & Technology, Kohat, Pakistan.<br /><searchLink fieldCode="AU" term="%22Ali+A%22">Ali A</searchLink>; Department of Zoology, Abdul Wali Khan University Mardan, Mardan, Pakistan.<br /><searchLink fieldCode="AU" term="%22Zaman+A%22">Zaman A</searchLink>; Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.; Department of Microbiology & Molecular Genetics, Bahauddin Zakariya University, Multan, Pakistan.<br /><searchLink fieldCode="AU" term="%22Shah+M%22">Shah M</searchLink>; Department of Biochemistry, Bahauddin Zakariya University, Multan, Pakistan.; Department of Animal Science, Federal University of Ceara, Fortaleza, Brazil.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2026 Mar 02; Vol. 21 (3), pp. e0343717. <i>Date of Electronic Publication: </i>2026 Mar 02 (<i>Print Publication: </i>2026).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101285081 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1932-6203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219326203%22">19326203 </searchLink><i>NLM ISO Abbreviation: </i>PLoS One <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41770783
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1371/journal.pone.0343717
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e0343717
    Titles:
      – TitleFull: Cheminformatics-driven discovery of natural isoquinoline alkaloid inhibitors of Beta-secretase I for Alzheimer's management.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Ahmad I
      – PersonEntity:
          Name:
            NameFull: Waheed S
      – PersonEntity:
          Name:
            NameFull: Alotaibi BS
      – PersonEntity:
          Name:
            NameFull: Abbasi SW
      – PersonEntity:
          Name:
            NameFull: Khan MU
      – PersonEntity:
          Name:
            NameFull: Rahman FU
      – PersonEntity:
          Name:
            NameFull: Dib H
      – PersonEntity:
          Name:
            NameFull: Fawy KF
      – PersonEntity:
          Name:
            NameFull: Nishan U
      – PersonEntity:
          Name:
            NameFull: Ali A
      – PersonEntity:
          Name:
            NameFull: Zaman A
      – PersonEntity:
          Name:
            NameFull: Shah M
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 02
              M: 03
              Text: 2026 Mar 02
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1932-6203
          Numbering:
            – Type: volume
              Value: 21
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: PloS one
              Type: main
ResultId 1