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Colorectal cancer in metabolic dysfunction-associated steatotic liver disease: an international Delphi consensus statement.

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Title: Colorectal cancer in metabolic dysfunction-associated steatotic liver disease: an international Delphi consensus statement.
Authors: Wu CT; Department of Gastroenterology, The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China., Targher G; Department of Medicine, University of Verona, Verona, Italy.; Metabolic Diseases Research Unit, IRCCS Sacro Cuore - Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy., Byrne CD; Southampton National Institute for Health and Care Research Biomedical Research Centre, University Hospital Southampton, and University of Southampton, Southampton General Hospital, Southampton, UK., Younossi ZM; The Global NASH/MASH Council, Washington, DC, USA.; Beatty Liver and Obesity Research Program, Inova Health System, Falls Church, VA, USA.; Center for Outcomes Research in Liver Diseases, Washington, DC, USA., Armstrong MJ; Liver Unit, Queen Elizabeth University Hospital, Birmingham, UK.; Birmingham NIHR Biomedical Research Centre, University of Birmingham, Birmingham, UK., Luu HN; Dr. Mary and Ron Neal Cancer Center, Houston Methodist Research Institute, Houston, Texas, USA.; Division of Cancer Control and Population Sciences, University of Pittsburgh Medical Center Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.; Department of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, USA., Lesmana CRA; Department of Internal Medicine, Hepatobiliary Division, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty, University of Indonesia, Jakarta, Indonesia.; Digestive Disease and GI Oncology Centre, Medistra Hospital, Jakarta, Indonesia., Rustgi VK; Division of Gastroenterology and Hepatology, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.; Center for Liver Diseases and Masses, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA., Thomas JA; Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.; Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia., Okabayashi K; Department of Surgery, Keio University School of Medicine, Tokyo, Japan., Lee JWJ; Division of Gastroenterology and Hepatology, National University Hospital, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; iHealthtech, National University of Singapore, Singapore., El-Serag HB; Department of Medicine, Section of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA., Kim W; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government Boramae Medical Center, Seoul, Korea., Zhang HJ; Department of Oncology, The Affiliated Zhongda Hospital of Southeast University, Nanjing, China., Lonardo A; Department of Internal Medicine, Ospedale Civile di Baggiovara (-2023), Azienda Ospedaliero-Universitaria di Modena, Modena, Italy., Souza M; Department of Internal Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., George ES; Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC, Australia., Yang W; Department of Metabolic and Bariatric Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China., Yilmaz Y; Department of Gastroenterology, School of Medicine, Recep Tayyip Erdoğan University, Rize, Türkiye., Papatheodoridis G; 1st Department of Gastroenterology, Medical School of National and Kapodistrian University of Athens, General Hospital of Athens 'Laiko', Athens, Greece., Sookoian S; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.; Department of Clinical and Molecular Hepatology, Translational Research in Health Center (CENITRES), Maimónides University, Buenos Aires, Argentina., Romero-Gómez M; Digestive Diseases Unit and CIBERehd, Virgen Del Rocío University Hospital, Sevilla, Spain.; Institute of Biomedicine of Seville (HUVR/CSIC/US), University of Seville, Sevilla, Spain., Sebastiani G; Division of Gastroenterology and Hepatology, Chronic Viral Illness Service, McGill University Health Centre, Royal Victoria Hospital, Montreal, Quebec, Canada., Schattenberg JM; Department of Medicine II, University Medical Center Homburg, Homburg and Saarland University, Saarbrücken, Germany., El-Kassas M; Department of Endemic Medicine, Faculty of Medicine, Helwan University, Cairo, Egypt.; Applied Science Research Center, Applied Science Private University, Amman, Jordan.; Steatotic Liver Disease Study Foundation in Middle East and North Africa (SLMENA), Cairo, Egypt., Chan WK; Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Ocama P; Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda., Lupșor-Platon M; Department of Medical Imaging, 'Prof. Dr. Octavian Fodor' Regional Institute of Gastroenterology and Hepatology, 'Iuliu Hațieganu' University of Medicine and Pharmacy, Cluj-Napoca, Romania., Perera N; Department of Medicine, University of Sri Jayewardenepura, Nugegoda, Sri Lanka., Alswat K; Liver Disease Research Center, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia., Méndez-Sánchez N; Liver Research Unit, Medica Sur Clinic & Foundation, Mexico City, Mexico.; Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico., Wong VW; Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China., Chai J; Department of Gastroenterology, the First Affiliated Hospital (Southwest Hospital) of Third Military Medical University (Army Medical University), Chongqing, China.; Institute of Digestive Diseases of PLA, the First Affiliated Hospital (Southwest Hospital) of Third Military Medical University (Army Medical University), Chongqing, China.; Cholestatic Liver Diseases Center and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Medical Research Center, the First Affiliated Hospital (Southwest Hospital) of Third Military Medical University (Army Medical University), Chongqing, China., Tilg H; Department of Internal Medicine I, Gastroenterology, Endocrinology & Metabolism, Medical University Innsbruck, Innsbruck, Austria., Sung JJ; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore zhengmh@wmu.edu.cn josephsung@ntu.edu.sg., Zheng MH; MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China zhengmh@wmu.edu.cn josephsung@ntu.edu.sg.; Key Laboratory of Diagnosis and Treatment for The Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China.
Source: Gut [Gut] 2026 Jan 21. Date of Electronic Publication: 2026 Jan 21.
Publication Type: Journal Article
Journal Info: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Wu+CT%22">Wu CT</searchLink>; Department of Gastroenterology, The Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Targher+G%22">Targher G</searchLink>; Department of Medicine, University of Verona, Verona, Italy.; Metabolic Diseases Research Unit, IRCCS Sacro Cuore - Don Calabria Hospital, Negrar di Valpolicella, Verona, Italy.<br /><searchLink fieldCode="AU" term="%22Byrne+CD%22">Byrne CD</searchLink>; Southampton National Institute for Health and Care Research Biomedical Research Centre, University Hospital Southampton, and University of Southampton, Southampton General Hospital, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Younossi+ZM%22">Younossi ZM</searchLink>; The Global NASH/MASH Council, Washington, DC, USA.; Beatty Liver and Obesity Research Program, Inova Health System, Falls Church, VA, USA.; Center for Outcomes Research in Liver Diseases, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Armstrong+MJ%22">Armstrong MJ</searchLink>; Liver Unit, Queen Elizabeth University Hospital, Birmingham, UK.; Birmingham NIHR Biomedical Research Centre, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Luu+HN%22">Luu HN</searchLink>; Dr. Mary and Ron Neal Cancer Center, Houston Methodist Research Institute, Houston, Texas, USA.; Division of Cancer Control and Population Sciences, University of Pittsburgh Medical Center Hillman Cancer Center, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.; Department of Epidemiology, University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Lesmana+CRA%22">Lesmana CRA</searchLink>; Department of Internal Medicine, Hepatobiliary Division, Dr. Cipto Mangunkusumo National General Hospital, Medical Faculty, University of Indonesia, Jakarta, Indonesia.; Digestive Disease and GI Oncology Centre, Medistra Hospital, Jakarta, Indonesia.<br /><searchLink fieldCode="AU" term="%22Rustgi+VK%22">Rustgi VK</searchLink>; Division of Gastroenterology and Hepatology, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.; Center for Liver Diseases and Masses, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+JA%22">Thomas JA</searchLink>; Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.; Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Okabayashi+K%22">Okabayashi K</searchLink>; Department of Surgery, Keio University School of Medicine, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Lee+JWJ%22">Lee JWJ</searchLink>; Division of Gastroenterology and Hepatology, National University Hospital, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; iHealthtech, National University of Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22El-Serag+HB%22">El-Serag HB</searchLink>; Department of Medicine, Section of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Kim+W%22">Kim W</searchLink>; Division of Gastroenterology and Hepatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government Boramae Medical Center, Seoul, Korea.<br /><searchLink fieldCode="AU" term="%22Zhang+HJ%22">Zhang HJ</searchLink>; Department of Oncology, The Affiliated Zhongda Hospital of Southeast University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Lonardo+A%22">Lonardo A</searchLink>; Department of Internal Medicine, Ospedale Civile di Baggiovara (-2023), Azienda Ospedaliero-Universitaria di Modena, Modena, Italy.<br /><searchLink fieldCode="AU" term="%22Souza+M%22">Souza M</searchLink>; Department of Internal Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22George+ES%22">George ES</searchLink>; Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Yang+W%22">Yang W</searchLink>; Department of Metabolic and Bariatric Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Yilmaz+Y%22">Yilmaz Y</searchLink>; Department of Gastroenterology, School of Medicine, Recep Tayyip Erdoğan University, Rize, Türkiye.<br /><searchLink fieldCode="AU" term="%22Papatheodoridis+G%22">Papatheodoridis G</searchLink>; 1st Department of Gastroenterology, Medical School of National and Kapodistrian University of Athens, General Hospital of Athens 'Laiko', Athens, Greece.<br /><searchLink fieldCode="AU" term="%22Sookoian+S%22">Sookoian S</searchLink>; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Buenos Aires, Argentina.; Department of Clinical and Molecular Hepatology, Translational Research in Health Center (CENITRES), Maimónides University, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Romero-Gómez+M%22">Romero-Gómez M</searchLink>; Digestive Diseases Unit and CIBERehd, Virgen Del Rocío University Hospital, Sevilla, Spain.; Institute of Biomedicine of Seville (HUVR/CSIC/US), University of Seville, Sevilla, Spain.<br /><searchLink fieldCode="AU" term="%22Sebastiani+G%22">Sebastiani G</searchLink>; Division of Gastroenterology and Hepatology, Chronic Viral Illness Service, McGill University Health Centre, Royal Victoria Hospital, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Schattenberg+JM%22">Schattenberg JM</searchLink>; Department of Medicine II, University Medical Center Homburg, Homburg and Saarland University, Saarbrücken, Germany.<br /><searchLink fieldCode="AU" term="%22El-Kassas+M%22">El-Kassas M</searchLink>; Department of Endemic Medicine, Faculty of Medicine, Helwan University, Cairo, Egypt.; Applied Science Research Center, Applied Science Private University, Amman, Jordan.; Steatotic Liver Disease Study Foundation in Middle East and North Africa (SLMENA), Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Chan+WK%22">Chan WK</searchLink>; Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.<br /><searchLink fieldCode="AU" term="%22Ocama+P%22">Ocama P</searchLink>; Department of Medicine, Makerere University College of Health Sciences, Kampala, Uganda.<br /><searchLink fieldCode="AU" term="%22Lupșor-Platon+M%22">Lupșor-Platon M</searchLink>; Department of Medical Imaging, 'Prof. Dr. Octavian Fodor' Regional Institute of Gastroenterology and Hepatology, 'Iuliu Hațieganu' University of Medicine and Pharmacy, Cluj-Napoca, Romania.<br /><searchLink fieldCode="AU" term="%22Perera+N%22">Perera N</searchLink>; Department of Medicine, University of Sri Jayewardenepura, Nugegoda, Sri Lanka.<br /><searchLink fieldCode="AU" term="%22Alswat+K%22">Alswat K</searchLink>; Liver Disease Research Center, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Méndez-Sánchez+N%22">Méndez-Sánchez N</searchLink>; Liver Research Unit, Medica Sur Clinic & Foundation, Mexico City, Mexico.; Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Wong+VW%22">Wong VW</searchLink>; Medical Data Analytics Centre, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.; State Key Laboratory of Digestive Disease, Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China.<br /><searchLink fieldCode="AU" term="%22Chai+J%22">Chai J</searchLink>; Department of Gastroenterology, the First Affiliated Hospital (Southwest Hospital) of Third Military Medical University (Army Medical University), Chongqing, China.; Institute of Digestive Diseases of PLA, the First Affiliated Hospital (Southwest Hospital) of Third Military Medical University (Army Medical University), Chongqing, China.; Cholestatic Liver Diseases Center and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Medical Research Center, the First Affiliated Hospital (Southwest Hospital) of Third Military Medical University (Army Medical University), Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Tilg+H%22">Tilg H</searchLink>; Department of Internal Medicine I, Gastroenterology, Endocrinology & Metabolism, Medical University Innsbruck, Innsbruck, Austria.<br /><searchLink fieldCode="AU" term="%22Sung+JJ%22">Sung JJ</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore zhengmh@wmu.edu.cn josephsung@ntu.edu.sg.<br /><searchLink fieldCode="AU" term="%22Zheng+MH%22">Zheng MH</searchLink>; MAFLD Research Center, Department of Hepatology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China zhengmh@wmu.edu.cn josephsung@ntu.edu.sg.; Key Laboratory of Diagnosis and Treatment for The Development of Chronic Liver Disease in Zhejiang Province, Wenzhou, China.
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