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CSF Proteomic Profiles Associated With White Matter Integrity in Cognitively Normal Older Adults With and Without Amyloid Pathology.

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Title: CSF Proteomic Profiles Associated With White Matter Integrity in Cognitively Normal Older Adults With and Without Amyloid Pathology.
Authors: Lorenzini L; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, Vrije Universiteit, the Netherlands.; Amsterdam Neuroscience, Brain Imaging, the Netherlands.; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Italy., Tranfa M; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, Vrije Universiteit, the Netherlands.; Department of Advanced Biomedical Sciences, University of Naples 'Federico II', Italy., Kate MT; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, Vrije Universiteit, the Netherlands.; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands., Braber AD; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Department of Biological Psychology, Vrije Universiteit Amsterdam, the Netherlands., Vermunt L; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, the Netherlands.; Neurochemistry Laboratory, Department of Laboratory Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam UMC, the Netherlands., Duits FH; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, the Netherlands., Lageman SB; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, the Netherlands.; Neurophysiology and MEG Center, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, the Netherlands., de Leeuw D; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, the Netherlands., Teunissen CE; Amsterdam Neuroscience, Neurodegeneration, the Netherlands.; Neurochemistry Laboratory, Department of Laboratory Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam UMC, the Netherlands., Garbarino S; Dipartimento di Matematica (DIMA), Università di Genova, Italy.; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Roccatagliata L; Department of Health Sciences (DISSAL), University of Genoa, Italy.; Department of Neuroradiology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Pardini M; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Italy.; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Van Der Flier WM; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, the Netherlands.; Department of Epidemiology & Biostatistics, Amsterdam Neuroscience, Amsterdam UMC, the Netherlands., Visser PJ; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, the Netherlands.; Department of Psychiatry, Maastricht University, the Netherlands; and., Barkhof F; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, Vrije Universiteit, the Netherlands.; Institutes of Neurology and Healthcare Engineering, University College London, United Kingdom., Tijms BM; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, the Netherlands.
Source: Neurology [Neurology] 2026 Apr 14; Vol. 106 (7), pp. e214675. Date of Electronic Publication: 2026 Mar 02.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0401060 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-632X (Electronic) Linking ISSN: 00283878 NLM ISO Abbreviation: Neurology Subsets: MEDLINE
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  Data: CSF Proteomic Profiles Associated With White Matter Integrity in Cognitively Normal Older Adults With and Without Amyloid Pathology.
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  Data: <searchLink fieldCode="AU" term="%22Lorenzini+L%22">Lorenzini L</searchLink>; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, Vrije Universiteit, the Netherlands.; Amsterdam Neuroscience, Brain Imaging, the Netherlands.; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Tranfa+M%22">Tranfa M</searchLink>; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, Vrije Universiteit, the Netherlands.; Department of Advanced Biomedical Sciences, University of Naples 'Federico II', Italy.<br /><searchLink fieldCode="AU" term="%22Kate+MT%22">Kate MT</searchLink>; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, Vrije Universiteit, the Netherlands.; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Braber+AD%22">Braber AD</searchLink>; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Department of Biological Psychology, Vrije Universiteit Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Vermunt+L%22">Vermunt L</searchLink>; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, the Netherlands.; Neurochemistry Laboratory, Department of Laboratory Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam UMC, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Duits+FH%22">Duits FH</searchLink>; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Lageman+SB%22">Lageman SB</searchLink>; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, the Netherlands.; Neurophysiology and MEG Center, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Leeuw+D%22">de Leeuw D</searchLink>; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Teunissen+CE%22">Teunissen CE</searchLink>; Amsterdam Neuroscience, Neurodegeneration, the Netherlands.; Neurochemistry Laboratory, Department of Laboratory Medicine, Amsterdam Neuroscience, VU University Medical Center, Amsterdam UMC, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Garbarino+S%22">Garbarino S</searchLink>; Dipartimento di Matematica (DIMA), Università di Genova, Italy.; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Roccatagliata+L%22">Roccatagliata L</searchLink>; Department of Health Sciences (DISSAL), University of Genoa, Italy.; Department of Neuroradiology, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Pardini+M%22">Pardini M</searchLink>; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genoa, Italy.; IRCCS Ospedale Policlinico San Martino, Genoa, Italy.<br /><searchLink fieldCode="AU" term="%22Van+Der+Flier+WM%22">Van Der Flier WM</searchLink>; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, the Netherlands.; Department of Epidemiology & Biostatistics, Amsterdam Neuroscience, Amsterdam UMC, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Visser+PJ%22">Visser PJ</searchLink>; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, the Netherlands.; Department of Psychiatry, Maastricht University, the Netherlands; and.<br /><searchLink fieldCode="AU" term="%22Barkhof+F%22">Barkhof F</searchLink>; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Centre, Vrije Universiteit, the Netherlands.; Institutes of Neurology and Healthcare Engineering, University College London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Tijms+BM%22">Tijms BM</searchLink>; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam UMC, the Netherlands.; Amsterdam Neuroscience, Neurodegeneration, the Netherlands.
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