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Defects in auxiliary fuel oxidation and mitochondrial pyruvate transport mark transition to overt heart failure in Tgαq*44 mice.

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Title: Defects in auxiliary fuel oxidation and mitochondrial pyruvate transport mark transition to overt heart failure in Tgαq*44 mice.
Authors: Olkowicz M; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, 30-348, Poland. m.olkowicz@gumed.edu.pl.; Department of Biopharmaceutics and Pharmacodynamics, Medical University of Gdansk, Hallera 107, Gdansk, 80-416, Poland. m.olkowicz@gumed.edu.pl., Jedrzejewska A; Department of Biochemistry, Medical University of Gdansk, Debinki 1, Gdansk, 80-211, Poland., Tyrankiewicz U; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, 30-348, Poland., Fedak FA; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, 30-348, Poland.; Doctoral School of Exact and Natural Sciences, Jagiellonian University, Lojasiewicza 11, Krakow, 30-348, Poland., Berkowicz P; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, 30-348, Poland., Kwiatkowski G; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, 30-348, Poland., Rosales-Solano H; Department of Chemistry, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada., Roy KS; Department of Chemistry, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada., Karas A; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, 30-348, Poland.; Doctoral School of Exact and Natural Sciences, Jagiellonian University, Lojasiewicza 11, Krakow, 30-348, Poland., Krol O; Department of Biochemistry, Medical University of Gdansk, Debinki 1, Gdansk, 80-211, Poland., Tomczyk M; Department of Biochemistry, Medical University of Gdansk, Debinki 1, Gdansk, 80-211, Poland., Smolenski RT; Department of Biochemistry, Medical University of Gdansk, Debinki 1, Gdansk, 80-211, Poland., Pawliszyn J; Department of Chemistry, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada., Chlopicki S; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, 30-348, Poland.; Department of Pharmacology, Jagiellonian University Medical College, Grzegorzecka 16, Krakow, 31-531, Poland.
Source: Journal of translational medicine [J Transl Med] 2026 Mar 03; Vol. 24 (1). Date of Electronic Publication: 2026 Mar 03.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Defects in auxiliary fuel oxidation and mitochondrial pyruvate transport mark transition to overt heart failure in Tgαq*44 mice.
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  Data: <searchLink fieldCode="AU" term="%22Olkowicz+M%22">Olkowicz M</searchLink>; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, 30-348, Poland. m.olkowicz@gumed.edu.pl.; Department of Biopharmaceutics and Pharmacodynamics, Medical University of Gdansk, Hallera 107, Gdansk, 80-416, Poland. m.olkowicz@gumed.edu.pl.<br /><searchLink fieldCode="AU" term="%22Jedrzejewska+A%22">Jedrzejewska A</searchLink>; Department of Biochemistry, Medical University of Gdansk, Debinki 1, Gdansk, 80-211, Poland.<br /><searchLink fieldCode="AU" term="%22Tyrankiewicz+U%22">Tyrankiewicz U</searchLink>; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, 30-348, Poland.<br /><searchLink fieldCode="AU" term="%22Fedak+FA%22">Fedak FA</searchLink>; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, 30-348, Poland.; Doctoral School of Exact and Natural Sciences, Jagiellonian University, Lojasiewicza 11, Krakow, 30-348, Poland.<br /><searchLink fieldCode="AU" term="%22Berkowicz+P%22">Berkowicz P</searchLink>; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, 30-348, Poland.<br /><searchLink fieldCode="AU" term="%22Kwiatkowski+G%22">Kwiatkowski G</searchLink>; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, 30-348, Poland.<br /><searchLink fieldCode="AU" term="%22Rosales-Solano+H%22">Rosales-Solano H</searchLink>; Department of Chemistry, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada.<br /><searchLink fieldCode="AU" term="%22Roy+KS%22">Roy KS</searchLink>; Department of Chemistry, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada.<br /><searchLink fieldCode="AU" term="%22Karas+A%22">Karas A</searchLink>; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, 30-348, Poland.; Doctoral School of Exact and Natural Sciences, Jagiellonian University, Lojasiewicza 11, Krakow, 30-348, Poland.<br /><searchLink fieldCode="AU" term="%22Krol+O%22">Krol O</searchLink>; Department of Biochemistry, Medical University of Gdansk, Debinki 1, Gdansk, 80-211, Poland.<br /><searchLink fieldCode="AU" term="%22Tomczyk+M%22">Tomczyk M</searchLink>; Department of Biochemistry, Medical University of Gdansk, Debinki 1, Gdansk, 80-211, Poland.<br /><searchLink fieldCode="AU" term="%22Smolenski+RT%22">Smolenski RT</searchLink>; Department of Biochemistry, Medical University of Gdansk, Debinki 1, Gdansk, 80-211, Poland.<br /><searchLink fieldCode="AU" term="%22Pawliszyn+J%22">Pawliszyn J</searchLink>; Department of Chemistry, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada.<br /><searchLink fieldCode="AU" term="%22Chlopicki+S%22">Chlopicki S</searchLink>; Jagiellonian Centre for Experimental Therapeutics (JCET), Jagiellonian University, Bobrzynskiego 14, Krakow, 30-348, Poland.; Department of Pharmacology, Jagiellonian University Medical College, Grzegorzecka 16, Krakow, 31-531, Poland.
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