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Neddylation-Mediated hnRNPA2B1 Degradation Aggravates Retinal Endothelial Cell Dysfunction in Diabetic Retinopathy by Regulating miR-93-5p/VEGFA.

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Title: Neddylation-Mediated hnRNPA2B1 Degradation Aggravates Retinal Endothelial Cell Dysfunction in Diabetic Retinopathy by Regulating miR-93-5p/VEGFA.
Authors: Chen TR; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China.; NHC Key Laboratory of Otorhinolaryngology, Qilu Hospital of Shandong University, Jinan, Shandong Province China.; Laboratory of Basic Medical Sciences, Qilu Hospital of Shandong University, Jinan, Shandong Province, China., Zhou JX; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China.; Laboratory of Basic Medical Sciences, Qilu Hospital of Shandong University, Jinan, Shandong Province, China., Hou YR; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China.; NHC Key Laboratory of Otorhinolaryngology, Qilu Hospital of Shandong University, Jinan, Shandong Province China.; Laboratory of Basic Medical Sciences, Qilu Hospital of Shandong University, Jinan, Shandong Province, China., Zhang YN; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China.; NHC Key Laboratory of Otorhinolaryngology, Qilu Hospital of Shandong University, Jinan, Shandong Province China.; Laboratory of Basic Medical Sciences, Qilu Hospital of Shandong University, Jinan, Shandong Province, China., Li CX; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China., Zhu J; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China., Guo ZR; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China.; NHC Key Laboratory of Otorhinolaryngology, Qilu Hospital of Shandong University, Jinan, Shandong Province China.; Laboratory of Basic Medical Sciences, Qilu Hospital of Shandong University, Jinan, Shandong Province, China., Cui Y; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China.
Source: Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2026 Mar 02; Vol. 67 (3), pp. 5.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Association For Research In Vision And Ophthalmology (Arvo) Country of Publication: United States NLM ID: 7703701 Publication Model: Print Cited Medium: Internet ISSN: 1552-5783 (Electronic) Linking ISSN: 01460404 NLM ISO Abbreviation: Invest Ophthalmol Vis Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Neddylation-Mediated hnRNPA2B1 Degradation Aggravates Retinal Endothelial Cell Dysfunction in Diabetic Retinopathy by Regulating miR-93-5p/VEGFA.
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  Data: <searchLink fieldCode="AU" term="%22Chen+TR%22">Chen TR</searchLink>; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China.; NHC Key Laboratory of Otorhinolaryngology, Qilu Hospital of Shandong University, Jinan, Shandong Province China.; Laboratory of Basic Medical Sciences, Qilu Hospital of Shandong University, Jinan, Shandong Province, China.<br /><searchLink fieldCode="AU" term="%22Zhou+JX%22">Zhou JX</searchLink>; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China.; Laboratory of Basic Medical Sciences, Qilu Hospital of Shandong University, Jinan, Shandong Province, China.<br /><searchLink fieldCode="AU" term="%22Hou+YR%22">Hou YR</searchLink>; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China.; NHC Key Laboratory of Otorhinolaryngology, Qilu Hospital of Shandong University, Jinan, Shandong Province China.; Laboratory of Basic Medical Sciences, Qilu Hospital of Shandong University, Jinan, Shandong Province, China.<br /><searchLink fieldCode="AU" term="%22Zhang+YN%22">Zhang YN</searchLink>; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China.; NHC Key Laboratory of Otorhinolaryngology, Qilu Hospital of Shandong University, Jinan, Shandong Province China.; Laboratory of Basic Medical Sciences, Qilu Hospital of Shandong University, Jinan, Shandong Province, China.<br /><searchLink fieldCode="AU" term="%22Li+CX%22">Li CX</searchLink>; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China.<br /><searchLink fieldCode="AU" term="%22Zhu+J%22">Zhu J</searchLink>; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China.<br /><searchLink fieldCode="AU" term="%22Guo+ZR%22">Guo ZR</searchLink>; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China.; NHC Key Laboratory of Otorhinolaryngology, Qilu Hospital of Shandong University, Jinan, Shandong Province China.; Laboratory of Basic Medical Sciences, Qilu Hospital of Shandong University, Jinan, Shandong Province, China.<br /><searchLink fieldCode="AU" term="%22Cui+Y%22">Cui Y</searchLink>; Department of Ophthalmology, Qilu Hospital of Shandong University, Shandong University, Jinan, Shandong Province, China.; School of Medicine, Shandong University, Jinan, Shandong Province, China.
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        Value: 10.1167/iovs.67.3.5
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      – TitleFull: Neddylation-Mediated hnRNPA2B1 Degradation Aggravates Retinal Endothelial Cell Dysfunction in Diabetic Retinopathy by Regulating miR-93-5p/VEGFA.
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              Text: 2026 Mar 02
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              Y: 2026
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