Promoting intervertebral disc fusion using BMP2, L51P, and the EP4 agonist KMN-159: synergistic osteogenesis in human annulus fibrosus cells.
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| Title: | Promoting intervertebral disc fusion using BMP2, L51P, and the EP4 agonist KMN-159: synergistic osteogenesis in human annulus fibrosus cells. |
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| Authors: | Chen S; Department of Orthopaedic Surgery & Traumatology, Inselspital, Bern University Hospital, Faculty of Medicine, University of Bern, CH-3010, Bern, Switzerland.; Tissue Engineering for Orthopaedics & Mechanobiology (TOM), Bone & Joint Program, Department for Bio-Medical Research (DBMR), Faculty of Medicine, University of Bern, CH-3008, Bern, Switzerland.; Graduate School for Cellular and Biomedical Sciences (GCB), University of Bern, CH-3012, Bern, Switzerland., Tian X; Center for Orthopaedic, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, 17475, Greifswald, Germany., Zwingenberger S; Center for Orthopaedic, Trauma Surgery and Rehabilitation Medicine, University Medicine Greifswald, 17475, Greifswald, Germany., Albers CE; Department of Orthopaedic Surgery & Traumatology, Inselspital, Bern University Hospital, Faculty of Medicine, University of Bern, CH-3010, Bern, Switzerland.; Orthopäädie Sonnenhof, KLG, CH-3006, Bern, Switzerland., Gantenbein B; Department of Orthopaedic Surgery & Traumatology, Inselspital, Bern University Hospital, Faculty of Medicine, University of Bern, CH-3010, Bern, Switzerland. benjamin.gantenbein@unibe.ch.; Tissue Engineering for Orthopaedics & Mechanobiology (TOM), Bone & Joint Program, Department for Bio-Medical Research (DBMR), Faculty of Medicine, University of Bern, CH-3008, Bern, Switzerland. benjamin.gantenbein@unibe.ch., Häckel S; Department of Orthopaedic Surgery & Traumatology, Inselspital, Bern University Hospital, Faculty of Medicine, University of Bern, CH-3010, Bern, Switzerland. sonja.haeckel@insel.ch.; Graduate School for Health Sciences(GHS), University of Bern, CH-3012, Bern, Switzerland. sonja.haeckel@insel.ch. |
| Source: | European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society [Eur Spine J] 2026 Jul; Vol. 35 (7), pp. 3784-3794. Date of Electronic Publication: 2026 Mar 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 9301980 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0932 (Electronic) Linking ISSN: 09406719 NLM ISO Abbreviation: Eur Spine J Subsets: MEDLINE; In Process |
| Database: | MEDLINE Ultimate |
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