MAGL Inhibition Relieves Psoriasiform Inflammation and Pruritus Via Modulation of ALOX12-12-HETE Axis in Mice.

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Title: MAGL Inhibition Relieves Psoriasiform Inflammation and Pruritus Via Modulation of ALOX12-12-HETE Axis in Mice.
Authors: Lin S; Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei, China., Liu X; Department of Dermatology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, Hubei, China., Jiang J; Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei, China.; Department of Dermatology, Institute of Dermatology, Peking University Shenzhen Hospital, Shenzhen Peking Unicersity-The Hong Kong University of Science and Technology Medical Center, Shenzhen, 518036, Guangdong, China., Ge W; Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China., Tao Q; Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei, China., Liu S; Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei, China., Zhanmu O; Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China., Yang Y; Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China., Li M; Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China. liman73@mails.tjmu.edu.cn., Chen H; Department of Dermatology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, Hubei, China. hongxiangchen@hotmail.com.; Shenzhen Nanshan People's Hospital, The 6th Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, 518052, Guangdong, China. hongxiangchen@hotmail.com.
Source: Inflammation [Inflammation] 2026 Mar 03; Vol. 49 (1). Date of Electronic Publication: 2026 Mar 03.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7600105 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-2576 (Electronic) Linking ISSN: 03603997 NLM ISO Abbreviation: Inflammation Subsets: MEDLINE
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  Data: MAGL Inhibition Relieves Psoriasiform Inflammation and Pruritus Via Modulation of ALOX12-12-HETE Axis in Mice.
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  Data: <searchLink fieldCode="AU" term="%22Lin+S%22">Lin S</searchLink>; Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Dermatology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Jiang+J%22">Jiang J</searchLink>; Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei, China.; Department of Dermatology, Institute of Dermatology, Peking University Shenzhen Hospital, Shenzhen Peking Unicersity-The Hong Kong University of Science and Technology Medical Center, Shenzhen, 518036, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Ge+W%22">Ge W</searchLink>; Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Tao+Q%22">Tao Q</searchLink>; Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Department of Dermatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Zhanmu+O%22">Zhanmu O</searchLink>; Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Department of Neurobiology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, Hubei, China. liman73@mails.tjmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Chen+H%22">Chen H</searchLink>; Department of Dermatology, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, 430071, Hubei, China. hongxiangchen@hotmail.com.; Shenzhen Nanshan People's Hospital, The 6th Affiliated Hospital of Shenzhen University Health Science Center, Shenzhen, 518052, Guangdong, China. hongxiangchen@hotmail.com.
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  Data: <searchLink fieldCode="JN" term="%227600105%22">Inflammation</searchLink> [Inflammation] 2026 Mar 03; Vol. 49 (1). <i>Date of Electronic Publication: </i>2026 Mar 03.
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        Value: 10.1007/s10753-025-02383-5
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        Text: English
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              Text: 2026 Mar 03
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              Y: 2026
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