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Semaglutide reduces murine blood pressure through the vascular smooth muscle GLP-1 receptor.

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Title: Semaglutide reduces murine blood pressure through the vascular smooth muscle GLP-1 receptor.
Authors: Medak KD; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada., Koehler JA; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada., Baggio LL; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada., Gonzalez-Rellan MJ; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada., Wong CK; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada., Cao X; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada., Rao V; Section of Nephrology, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Kao S; Section of Nephrology, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Cui Y; Section of Nephrology, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Fu J; Section of Nephrology, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Liaw E; Section of Nephrology, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Kabir MG; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada., Zhang J; Section of Nephrology, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Wei J; Section of Nephrology, Department of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Drucker DJ; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada.
Source: JCI insight [JCI Insight] 2026 Mar 03; Vol. 11 (8). Date of Electronic Publication: 2026 Mar 03 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2379-3708
DOI:10.1172/jci.insight.201148