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Mesenchymal stromal cells modulate survival and regeneration of human hematopoietic stem cells via PGE2/cAMP signaling.

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Title: Mesenchymal stromal cells modulate survival and regeneration of human hematopoietic stem cells via PGE2/cAMP signaling.
Authors: Muddineni SSNA; Department of Pathology, Tel Aviv University, Tel-Aviv, Israel.; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel., Katz-Even C; Department of Pathology, Tel Aviv University, Tel-Aviv, Israel.; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel., Zipin-Roitman A; Department of Pathology, Tel Aviv University, Tel-Aviv, Israel.; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel., Rasoulouniriana D; Department of Pathology, Tel Aviv University, Tel-Aviv, Israel.; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel., Singha Roy D; Department of Pathology, Tel Aviv University, Tel-Aviv, Israel.; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel., Aborgies R; Department of Pathology, Tel Aviv University, Tel-Aviv, Israel.; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel., Beider K; Hematology Division, Chaim Sheba Medical Center, Tel-Hashomer, Israel., Raz Y; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel.; Department of Obstetrics and Gynecology, Gynecologic Oncology Division, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel-Aviv, Israel., Solomon N; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel.; Department of Obstetrics and Gynecology, Gynecologic Oncology Division, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel-Aviv, Israel., Hershkovitz G; Department of Obstetrics and Gynecology, Gynecologic Oncology Division, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel-Aviv, Israel., Shulman Y; Department of Obstetrics and Gynecology, Gynecologic Oncology Division, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel-Aviv, Israel., Chen R; Helen Schneider Hospital for Women, Rabin Medical Center, Petach-Tikva, Israel., Weizman E; G-INCPM, Weizmann Institute of Science, Rehovot, Israel., Waskow C; Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany.; Institute of Biochemistry and Biophysics, Faculty of Biological Sciences, Friedrich-Schiller-University, Jena, Germany., Nagler A; Hematology Division, Chaim Sheba Medical Center, Tel-Hashomer, Israel., Milyavsky M; Department of Pathology, Tel Aviv University, Tel-Aviv, Israel. mmilyavsky@post.tau.ac.il.; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel. mmilyavsky@post.tau.ac.il.
Source: Cell death & disease [Cell Death Dis] 2026 Mar 03; Vol. 17 (1). Date of Electronic Publication: 2026 Mar 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mesenchymal stromal cells modulate survival and regeneration of human hematopoietic stem cells via PGE2/cAMP signaling.
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  Data: <searchLink fieldCode="AU" term="%22Muddineni+SSNA%22">Muddineni SSNA</searchLink>; Department of Pathology, Tel Aviv University, Tel-Aviv, Israel.; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Katz-Even+C%22">Katz-Even C</searchLink>; Department of Pathology, Tel Aviv University, Tel-Aviv, Israel.; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Zipin-Roitman+A%22">Zipin-Roitman A</searchLink>; Department of Pathology, Tel Aviv University, Tel-Aviv, Israel.; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Rasoulouniriana+D%22">Rasoulouniriana D</searchLink>; Department of Pathology, Tel Aviv University, Tel-Aviv, Israel.; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Singha+Roy+D%22">Singha Roy D</searchLink>; Department of Pathology, Tel Aviv University, Tel-Aviv, Israel.; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Aborgies+R%22">Aborgies R</searchLink>; Department of Pathology, Tel Aviv University, Tel-Aviv, Israel.; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Beider+K%22">Beider K</searchLink>; Hematology Division, Chaim Sheba Medical Center, Tel-Hashomer, Israel.<br /><searchLink fieldCode="AU" term="%22Raz+Y%22">Raz Y</searchLink>; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel.; Department of Obstetrics and Gynecology, Gynecologic Oncology Division, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Solomon+N%22">Solomon N</searchLink>; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel.; Department of Obstetrics and Gynecology, Gynecologic Oncology Division, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Hershkovitz+G%22">Hershkovitz G</searchLink>; Department of Obstetrics and Gynecology, Gynecologic Oncology Division, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Shulman+Y%22">Shulman Y</searchLink>; Department of Obstetrics and Gynecology, Gynecologic Oncology Division, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Tel-Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Chen+R%22">Chen R</searchLink>; Helen Schneider Hospital for Women, Rabin Medical Center, Petach-Tikva, Israel.<br /><searchLink fieldCode="AU" term="%22Weizman+E%22">Weizman E</searchLink>; G-INCPM, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Waskow+C%22">Waskow C</searchLink>; Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany.; Institute of Biochemistry and Biophysics, Faculty of Biological Sciences, Friedrich-Schiller-University, Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Nagler+A%22">Nagler A</searchLink>; Hematology Division, Chaim Sheba Medical Center, Tel-Hashomer, Israel.<br /><searchLink fieldCode="AU" term="%22Milyavsky+M%22">Milyavsky M</searchLink>; Department of Pathology, Tel Aviv University, Tel-Aviv, Israel. mmilyavsky@post.tau.ac.il.; Gray Faculty of Medical & Health Sciences, Tel Aviv University, Tel-Aviv, Israel. mmilyavsky@post.tau.ac.il.
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