Patient-derived complex organoids are a critical tool to understand and explore pediatric malignant brain tumors.
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| Title: | Patient-derived complex organoids are a critical tool to understand and explore pediatric malignant brain tumors. |
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| Authors: | Deschuyter M; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France. deschuyter@unistra.fr.; UMR CNRS 7021, Laboratory of Bioimaging and Pathologies, Translational, Transversal and Therapeutic Oncology Team, OnKO-3T, Faculty of Pharmacy, Illkirch, France. deschuyter@unistra.fr., Martin S; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; UMR CNRS 7021, Laboratory of Bioimaging and Pathologies, Translational, Transversal and Therapeutic Oncology Team, OnKO-3T, Faculty of Pharmacy, Illkirch, France., Salmanli C; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; UMR CNRS 7021, Laboratory of Bioimaging and Pathologies, Translational, Transversal and Therapeutic Oncology Team, OnKO-3T, Faculty of Pharmacy, Illkirch, France., Hubsch C; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; UMR CNRS 7021, Laboratory of Bioimaging and Pathologies, Translational, Transversal and Therapeutic Oncology Team, OnKO-3T, Faculty of Pharmacy, Illkirch, France., Vincent A; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; OrgaRes Platform, Lille, France.; University of Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity Plasticity and Resistance to Therapies, Lille, France., Meignan S; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; University of Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity Plasticity and Resistance to Therapies, Lille, France.; Tumorigenesis and Resistance to Treatment Unit, Centre Oscar Lambret, Lille, France., Furlan A; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; University of Lille, CNRS, Inserm, CHU Lille, UMR9020-U1277-CANTHER-Cancer Heterogeneity Plasticity and Resistance to Therapies, Lille, France.; Tumorigenesis and Resistance to Treatment Unit, Centre Oscar Lambret, Lille, France., Cosset E; GLIMMER Of lIght (GLIoblastoma MetabolisM, HetERogeneity, and OrganoIds), Cancer Research Centre of Lyon, INSERM U1052, CNRS UMR 5286, Lyon, France., Burckel H; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; Radiobiology Laboratory, Institut Strauss, Unicancer, Strasbourg, France.; CNRS ICube UMR 7357, University of Strasbourg, Strasbourg, France., Noel G; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; Radiobiology Laboratory, Institut Strauss, Unicancer, Strasbourg, France.; CNRS ICube UMR 7357, University of Strasbourg, Strasbourg, France., Salzet M; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; Laboratory PRISM-U1192, University of Lille, Lille, France., Duhamel M; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; Laboratory PRISM-U1192, University of Lille, Lille, France., Raffo-Romero A; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; Laboratory PRISM-U1192, University of Lille, Lille, France., Boura C; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; CRAN UMR 7039 UL, CNRS, Département BioSiS, Vandoeuvre Les Nancy, France., Pinel S; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; CRAN UMR 7039 UL, CNRS, Département BioSiS, Vandoeuvre Les Nancy, France., Coca A; Neurosurgery Department, University Hospitals of Strasbourg, Strasbourg, France., Joud A; Neurosurgery Department, University Hospital of Nancy, Vandoeuvre Les Nancy, France., Karnoub MA; Neurosurgery Department, University Hospital of Lille, Lille, France., Chastagner P; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; CRAN UMR 7039 UL, CNRS, Département BioSiS, Vandoeuvre Les Nancy, France.; Pediatric Onco-Hematology Department, University Hospital of Nancy, Vandoeuvre Les Nancy, France., Raimbault S; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; Pediatric Oncology, Centre Oscar Lambret, Lille, France., Sudour-Bonnange H; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; Pediatric Oncology, Centre Oscar Lambret, Lille, France., Flacher V; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France.; CNRS UPR3572, Laboratory I2CT, Immunology, Immunopathology and Therapeutic Chemistry, Strasbourg Drug Discovery and Development Institute (IMS), Institut de Biologie Moléculaire et Cellulaire (IBMC), Strasbourg, France., Bernhard C; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France., Entz-Werlé N; EN-HOPE SMART4CBT Research Center, PEDIACRIEX, Lille, Nancy, Strasbourg, University Hospitals of Strasbourg, Strasbourg, France. Natacha.entz-werle@chru-strasbourg.fr.; UMR CNRS 7021, Laboratory of Bioimaging and Pathologies, Translational, Transversal and Therapeutic Oncology Team, OnKO-3T, Faculty of Pharmacy, Illkirch, France. Natacha.entz-werle@chru-strasbourg.fr.; Pediatric Onco-Hematology Unit, University Hospitals of Strasbourg, Strasbourg, France. Natacha.entz-werle@chru-strasbourg.fr. |
| Source: | Cancer metastasis reviews [Cancer Metastasis Rev] 2026 Mar 03; Vol. 45 (1). Date of Electronic Publication: 2026 Mar 03. |
| Publication Type: | Journal Article; Review; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 8605731 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-7233 (Electronic) Linking ISSN: 01677659 NLM ISO Abbreviation: Cancer Metastasis Rev Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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