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Disruption of the angiopoietin-like system connects lipid homeostasis and hypothalamic dysfunction in ALS.

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Title: Disruption of the angiopoietin-like system connects lipid homeostasis and hypothalamic dysfunction in ALS.
Authors: Krishnamurthy SS; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany.; CEMMA Graduate School, Ulm University, Ulm, 80981, Germany., Buzatto AZ; Department of Biological Sciences, University of Calgary, Calgary, AB, T2N 1N4, Canada., Campkin C; The Metabolomics Innovation Centre, University of Alberta, Edmonton, AB, T6G 2R3, Canada., Müller HP; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany., Wiesner D; German Center for Neurodegenerative Diseases (DZNE), Ulm, 89081, Germany., Weishaupt J; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany., Klose V; German Center for Neurodegenerative Diseases (DZNE), Ulm, 89081, Germany., Wiesenfarth M; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany., Elmas Z; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany., Herrmann C; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany., Parlak Ö; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany., Günther K; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany., Saad R; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany., Weiland U; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany., Dupuis L; Université de Strasbourg, Inserm, UMR-S 1329, Strasbourg, 67081, France., Ludolph A; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany.; German Center for Neurodegenerative Diseases (DZNE), Ulm, 89081, Germany., Li L; The Metabolomics Innovation Centre, University of Alberta, Edmonton, AB, T6G 2R3, Canada.; Department of Chemistry, University of Alberta, Edmonton, AB, T6G 2R3, Canada., Kassubek J; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany., Dorst J; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany., Roselli F; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany. francesco.roselli@uni-ulm.de.; German Center for Neurodegenerative Diseases (DZNE), Ulm, 89081, Germany. francesco.roselli@uni-ulm.de.
Source: BMC medicine [BMC Med] 2026 Mar 03; Vol. 24 (1). Date of Electronic Publication: 2026 Mar 03.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190723 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7015 (Electronic) Linking ISSN: 17417015 NLM ISO Abbreviation: BMC Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Disruption of the angiopoietin-like system connects lipid homeostasis and hypothalamic dysfunction in ALS.
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  Data: <searchLink fieldCode="AU" term="%22Krishnamurthy+SS%22">Krishnamurthy SS</searchLink>; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany.; CEMMA Graduate School, Ulm University, Ulm, 80981, Germany.<br /><searchLink fieldCode="AU" term="%22Buzatto+AZ%22">Buzatto AZ</searchLink>; Department of Biological Sciences, University of Calgary, Calgary, AB, T2N 1N4, Canada.<br /><searchLink fieldCode="AU" term="%22Campkin+C%22">Campkin C</searchLink>; The Metabolomics Innovation Centre, University of Alberta, Edmonton, AB, T6G 2R3, Canada.<br /><searchLink fieldCode="AU" term="%22Müller+HP%22">Müller HP</searchLink>; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Wiesner+D%22">Wiesner D</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Ulm, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Weishaupt+J%22">Weishaupt J</searchLink>; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Klose+V%22">Klose V</searchLink>; German Center for Neurodegenerative Diseases (DZNE), Ulm, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Wiesenfarth+M%22">Wiesenfarth M</searchLink>; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Elmas+Z%22">Elmas Z</searchLink>; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Herrmann+C%22">Herrmann C</searchLink>; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Parlak+Ö%22">Parlak Ö</searchLink>; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Günther+K%22">Günther K</searchLink>; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Saad+R%22">Saad R</searchLink>; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Weiland+U%22">Weiland U</searchLink>; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Dupuis+L%22">Dupuis L</searchLink>; Université de Strasbourg, Inserm, UMR-S 1329, Strasbourg, 67081, France.<br /><searchLink fieldCode="AU" term="%22Ludolph+A%22">Ludolph A</searchLink>; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany.; German Center for Neurodegenerative Diseases (DZNE), Ulm, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; The Metabolomics Innovation Centre, University of Alberta, Edmonton, AB, T6G 2R3, Canada.; Department of Chemistry, University of Alberta, Edmonton, AB, T6G 2R3, Canada.<br /><searchLink fieldCode="AU" term="%22Kassubek+J%22">Kassubek J</searchLink>; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Dorst+J%22">Dorst J</searchLink>; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany.<br /><searchLink fieldCode="AU" term="%22Roselli+F%22">Roselli F</searchLink>; Department of Neurology, Ulm University, Center for Biomedical Research (ZBF), Helmholtzstrasse 8/2, Ulm, 89081, Germany. francesco.roselli@uni-ulm.de.; German Center for Neurodegenerative Diseases (DZNE), Ulm, 89081, Germany. francesco.roselli@uni-ulm.de.
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  Data: <searchLink fieldCode="JN" term="%22101190723%22">BMC medicine</searchLink> [BMC Med] 2026 Mar 03; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Mar 03.
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              Text: 2026 Mar 03
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