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Doxorubicin enhances adipogenesis in an FGF2-dependent manner and induces a tumour-promoting secretory phenotype.

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Title: Doxorubicin enhances adipogenesis in an FGF2-dependent manner and induces a tumour-promoting secretory phenotype.
Authors: Kreps LM; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada., Yakubovich E; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada.; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada., Zhao H; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada., Yimer S; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada.; Translational and Molecular Medicine Program, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada., Yang E; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada., Cruz J; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada.; Translational and Molecular Medicine Program, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada., Vanderhyden B; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada.; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada., Addison CL; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada.; Department of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada.
Source: Journal of bone oncology [J Bone Oncol] 2026 Feb 21; Vol. 57, pp. 100754. Date of Electronic Publication: 2026 Feb 21 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101610292 Publication Model: eCollection Cited Medium: Print ISSN: 2212-1366 (Print) Linking ISSN: 22121366 NLM ISO Abbreviation: J Bone Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Doxorubicin enhances adipogenesis in an FGF2-dependent manner and induces a tumour-promoting secretory phenotype.
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  Data: <searchLink fieldCode="AU" term="%22Kreps+LM%22">Kreps LM</searchLink>; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Yakubovich+E%22">Yakubovich E</searchLink>; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada.; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Zhao+H%22">Zhao H</searchLink>; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Yimer+S%22">Yimer S</searchLink>; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada.; Translational and Molecular Medicine Program, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Yang+E%22">Yang E</searchLink>; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Cruz+J%22">Cruz J</searchLink>; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada.; Translational and Molecular Medicine Program, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Vanderhyden+B%22">Vanderhyden B</searchLink>; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada.; Department of Cellular and Molecular Medicine, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Addison+CL%22">Addison CL</searchLink>; Cancer Research Program, Ottawa Hospital Research Institute, 501 Smyth Road, Ottawa, Ontario, Canada.; Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada.; Department of Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101610292%22">Journal of bone oncology</searchLink> [J Bone Oncol] 2026 Feb 21; Vol. 57, pp. 100754. <i>Date of Electronic Publication: </i>2026 Feb 21 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101610292 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2212-1366 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222121366%22">22121366 </searchLink><i>NLM ISO Abbreviation: </i>J Bone Oncol <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1016/j.jbo.2026.100754
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        Text: English
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              Text: 2026 Feb 21
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