Prothrombin G20210A and Factor V Leiden Variants Are Not Associated With Thrombotic Events in Congenital Heart Disease: An Observational Trial.

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Title: Prothrombin G20210A and Factor V Leiden Variants Are Not Associated With Thrombotic Events in Congenital Heart Disease: An Observational Trial.
Authors: Ladha FA; Department of Pediatrics Boston Children's Hospital Boston MA., VanderPluym C; Department of Cardiology Boston Children's Hospital Boston MA., Mondragon-Estrada E; Division of Newborn Medicine, Department of Pediatrics Boston Children's Hospital Boston MA.; Fetal Neonatal Neuroimaging and Developmental Science Center Boston Children's Hospital Boston MA., Avillach P; Computational Health Informatics Program Boston Children's Hospital Boston MA.; Department of Pediatrics Harvard Medical School Boston MA.; Department of Epidemiology Harvard T. H. Chan School of Public Health Boston MA., Brueckner M; Department of Genetics and Pediatrics Yale University School of Medicine New Haven CT., Chung WK; Department of Pediatrics Boston Children's Hospital Boston MA.; Department of Pediatrics Harvard Medical School Boston MA.; Department of Pediatrics and Medicine Columbia University Medical Center New York NY., Cnota JF; Heart Institute, Cincinnati Children's Hospital Medical Center Cincinnati OH.; Mindich Child Health and Development Institute and Department of Pediatrics, Icahn School of Medicine at Mount Sinai New York NY., Gelb BD; Mindich Child Health and Development Institute and Department of Pediatrics, Icahn School of Medicine at Mount Sinai New York NY., Lewis M; Division of Cardiology, Department of Medicine Columbia University New York NY., Liu C; Division of Genetics and Genomics, Department of Pediatrics Boston Children's Hospital Boston MA., Roberts AE; Department of Pediatrics Boston Children's Hospital Boston MA.; Department of Cardiology Boston Children's Hospital Boston MA.; Division of Genetics, Department of Pediatrics Boston Children's Hospital Boston MA., Seidman CE; Division of Genetics, Department of Pediatrics Boston Children's Hospital Boston MA.; Department of Cardiology Brigham and Women's Hospital Boston MA., Tristani-Firouzi M; Division of Pediatric Cardiology University of Utah School of Medicine Salt Lake City UT., Wagner M; Divisions of Biomedical Informatics and of Biostatistics and Epidemiology Cincinnati Children's Hospital Medical Center Cincinnati OH.; Department of Pediatrics University of Cincinnati College of Medicine Cincinnati OH., Morton SU; Division of Newborn Medicine, Department of Pediatrics Boston Children's Hospital Boston MA.; Department of Pediatrics Harvard Medical School Boston MA., Newburger JW; Department of Cardiology Boston Children's Hospital Boston MA.; Department of Pediatrics Harvard Medical School Boston MA.
Corporate Authors: Pediatric Cardiac Genomics Consortium Investigators
Source: Journal of the American Heart Association [J Am Heart Assoc] 2026 Mar 17; Vol. 15 (6), pp. e046959. Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article; Observational Study; Multicenter Study
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Prothrombin G20210A and Factor V Leiden Variants Are Not Associated With Thrombotic Events in Congenital Heart Disease: An Observational Trial.
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  Data: <searchLink fieldCode="AU" term="%22Ladha+FA%22">Ladha FA</searchLink>; Department of Pediatrics Boston Children's Hospital Boston MA.<br /><searchLink fieldCode="AU" term="%22VanderPluym+C%22">VanderPluym C</searchLink>; Department of Cardiology Boston Children's Hospital Boston MA.<br /><searchLink fieldCode="AU" term="%22Mondragon-Estrada+E%22">Mondragon-Estrada E</searchLink>; Division of Newborn Medicine, Department of Pediatrics Boston Children's Hospital Boston MA.; Fetal Neonatal Neuroimaging and Developmental Science Center Boston Children's Hospital Boston MA.<br /><searchLink fieldCode="AU" term="%22Avillach+P%22">Avillach P</searchLink>; Computational Health Informatics Program Boston Children's Hospital Boston MA.; Department of Pediatrics Harvard Medical School Boston MA.; Department of Epidemiology Harvard T. H. Chan School of Public Health Boston MA.<br /><searchLink fieldCode="AU" term="%22Brueckner+M%22">Brueckner M</searchLink>; Department of Genetics and Pediatrics Yale University School of Medicine New Haven CT.<br /><searchLink fieldCode="AU" term="%22Chung+WK%22">Chung WK</searchLink>; Department of Pediatrics Boston Children's Hospital Boston MA.; Department of Pediatrics Harvard Medical School Boston MA.; Department of Pediatrics and Medicine Columbia University Medical Center New York NY.<br /><searchLink fieldCode="AU" term="%22Cnota+JF%22">Cnota JF</searchLink>; Heart Institute, Cincinnati Children's Hospital Medical Center Cincinnati OH.; Mindich Child Health and Development Institute and Department of Pediatrics, Icahn School of Medicine at Mount Sinai New York NY.<br /><searchLink fieldCode="AU" term="%22Gelb+BD%22">Gelb BD</searchLink>; Mindich Child Health and Development Institute and Department of Pediatrics, Icahn School of Medicine at Mount Sinai New York NY.<br /><searchLink fieldCode="AU" term="%22Lewis+M%22">Lewis M</searchLink>; Division of Cardiology, Department of Medicine Columbia University New York NY.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Division of Genetics and Genomics, Department of Pediatrics Boston Children's Hospital Boston MA.<br /><searchLink fieldCode="AU" term="%22Roberts+AE%22">Roberts AE</searchLink>; Department of Pediatrics Boston Children's Hospital Boston MA.; Department of Cardiology Boston Children's Hospital Boston MA.; Division of Genetics, Department of Pediatrics Boston Children's Hospital Boston MA.<br /><searchLink fieldCode="AU" term="%22Seidman+CE%22">Seidman CE</searchLink>; Division of Genetics, Department of Pediatrics Boston Children's Hospital Boston MA.; Department of Cardiology Brigham and Women's Hospital Boston MA.<br /><searchLink fieldCode="AU" term="%22Tristani-Firouzi+M%22">Tristani-Firouzi M</searchLink>; Division of Pediatric Cardiology University of Utah School of Medicine Salt Lake City UT.<br /><searchLink fieldCode="AU" term="%22Wagner+M%22">Wagner M</searchLink>; Divisions of Biomedical Informatics and of Biostatistics and Epidemiology Cincinnati Children's Hospital Medical Center Cincinnati OH.; Department of Pediatrics University of Cincinnati College of Medicine Cincinnati OH.<br /><searchLink fieldCode="AU" term="%22Morton+SU%22">Morton SU</searchLink>; Division of Newborn Medicine, Department of Pediatrics Boston Children's Hospital Boston MA.; Department of Pediatrics Harvard Medical School Boston MA.<br /><searchLink fieldCode="AU" term="%22Newburger+JW%22">Newburger JW</searchLink>; Department of Cardiology Boston Children's Hospital Boston MA.; Department of Pediatrics Harvard Medical School Boston MA.
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  Data: <searchLink fieldCode="JN" term="%22101580524%22">Journal of the American Heart Association</searchLink> [J Am Heart Assoc] 2026 Mar 17; Vol. 15 (6), pp. e046959. <i>Date of Electronic Publication: </i>2026 Mar 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley-Blackwell%22">Wiley-Blackwell </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101580524 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2047-9980 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220479980%22">20479980 </searchLink><i>NLM ISO Abbreviation: </i>J Am Heart Assoc <i>Subsets: </i>MEDLINE
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        Value: 10.1161/JAHA.125.046959
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      – TitleFull: Prothrombin G20210A and Factor V Leiden Variants Are Not Associated With Thrombotic Events in Congenital Heart Disease: An Observational Trial.
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