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Esketamine Alleviates Postoperative Cognitive Dysfunction via Rock2/Add1 Signaling Pathway in Aged Mice.

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Title: Esketamine Alleviates Postoperative Cognitive Dysfunction via Rock2/Add1 Signaling Pathway in Aged Mice.
Authors: Xu C; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China., Zhang Y; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China., Liu Y; Ningxia Key Laboratory of Craniocerebral Diseases, Ningxia Medical University, Yinchuan, 750004, Ningxia, China., Niu X; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China., Zhang C; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China., Zhao N; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China., Wu Y; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China., Ma H; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China., Wen Y; Ningxia Key Laboratory of Craniocerebral Diseases, Ningxia Medical University, Yinchuan, 750004, Ningxia, China. wenyj@nxmu.edu.cn., Ni X; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China. xinlini6@nyfy.com.cn.
Source: Neurochemical research [Neurochem Res] 2026 Mar 04; Vol. 51 (2). Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article
Journal Info: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 7613461 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6903 (Electronic) Linking ISSN: 03643190 NLM ISO Abbreviation: Neurochem Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Esketamine Alleviates Postoperative Cognitive Dysfunction via Rock2/Add1 Signaling Pathway in Aged Mice.
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  Data: <searchLink fieldCode="AU" term="%22Xu+C%22">Xu C</searchLink>; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China.<br /><searchLink fieldCode="AU" term="%22Liu+Y%22">Liu Y</searchLink>; Ningxia Key Laboratory of Craniocerebral Diseases, Ningxia Medical University, Yinchuan, 750004, Ningxia, China.<br /><searchLink fieldCode="AU" term="%22Niu+X%22">Niu X</searchLink>; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China.<br /><searchLink fieldCode="AU" term="%22Zhang+C%22">Zhang C</searchLink>; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China.<br /><searchLink fieldCode="AU" term="%22Zhao+N%22">Zhao N</searchLink>; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China.<br /><searchLink fieldCode="AU" term="%22Ma+H%22">Ma H</searchLink>; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China.<br /><searchLink fieldCode="AU" term="%22Wen+Y%22">Wen Y</searchLink>; Ningxia Key Laboratory of Craniocerebral Diseases, Ningxia Medical University, Yinchuan, 750004, Ningxia, China. wenyj@nxmu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Ni+X%22">Ni X</searchLink>; Department of Anesthesiology and Perioperative Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China. xinlini6@nyfy.com.cn.
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  Data: <searchLink fieldCode="JN" term="%227613461%22">Neurochemical research</searchLink> [Neurochem Res] 2026 Mar 04; Vol. 51 (2). <i>Date of Electronic Publication: </i>2026 Mar 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Kluwer+Academic%2FPlenum+Publishers%22">Kluwer Academic/Plenum Publishers </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7613461 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-6903 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203643190%22">03643190 </searchLink><i>NLM ISO Abbreviation: </i>Neurochem Res <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s11064-026-04710-0
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        Text: English
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            – D: 04
              M: 03
              Text: 2026 Mar 04
              Type: published
              Y: 2026
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