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Nanoparticle based siRNA therapeutics for ovarian cancer overcoming drug resistance and future directions.

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Title: Nanoparticle based siRNA therapeutics for ovarian cancer overcoming drug resistance and future directions.
Authors: Di Fonte R; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124, Bari, Italy., Bolognino I; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124, Bari, Italy., Sommonte F; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124, Bari, Italy., Serratì S; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124, Bari, Italy., Fasano R; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124, Bari, Italy., Arduino I; Department of Pharmacy-Pharmaceutical Sciences, University of Bari, 70125, Bari, Italy., Iacobazzi RM; Department of Pharmacy-Pharmaceutical Sciences, University of Bari, 70125, Bari, Italy., Denora N; Department of Pharmacy-Pharmaceutical Sciences, University of Bari, 70125, Bari, Italy., Perego P; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133, Milano, Italy., Rossi G; Unit of Neurology V and Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133, Milano, Italy., Tosi D; Early Clinical Trial Unit, Medical Oncology Department, Institut régional du Cancer de Montpellier, Inserm U1194, Montpellier University, Montpellier, France.; Fondazione Gianni Bonadonna, 20154, Milano, Italy., Porcelli L; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124, Bari, Italy., Azzariti A; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124, Bari, Italy. a.azzariti@oncologico.bari.it.
Source: Discover nano [Discov Nano] 2026 Mar 04; Vol. 21 (1). Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article; Review
Journal Info: Publisher: Springer Nature Switzerland Country of Publication: Switzerland NLM ID: 9918540788706676 Publication Model: Electronic Cited Medium: Internet ISSN: 2731-9229 (Electronic) Linking ISSN: 27319229 NLM ISO Abbreviation: Discov Nano Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Nanoparticle based siRNA therapeutics for ovarian cancer overcoming drug resistance and future directions.
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  Data: <searchLink fieldCode="AU" term="%22Di+Fonte+R%22">Di Fonte R</searchLink>; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Bolognino+I%22">Bolognino I</searchLink>; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Sommonte+F%22">Sommonte F</searchLink>; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Serratì+S%22">Serratì S</searchLink>; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Fasano+R%22">Fasano R</searchLink>; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Arduino+I%22">Arduino I</searchLink>; Department of Pharmacy-Pharmaceutical Sciences, University of Bari, 70125, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Iacobazzi+RM%22">Iacobazzi RM</searchLink>; Department of Pharmacy-Pharmaceutical Sciences, University of Bari, 70125, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Denora+N%22">Denora N</searchLink>; Department of Pharmacy-Pharmaceutical Sciences, University of Bari, 70125, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Perego+P%22">Perego P</searchLink>; Molecular Pharmacology Unit, Department of Experimental Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Rossi+G%22">Rossi G</searchLink>; Unit of Neurology V and Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Tosi+D%22">Tosi D</searchLink>; Early Clinical Trial Unit, Medical Oncology Department, Institut régional du Cancer de Montpellier, Inserm U1194, Montpellier University, Montpellier, France.; Fondazione Gianni Bonadonna, 20154, Milano, Italy.<br /><searchLink fieldCode="AU" term="%22Porcelli+L%22">Porcelli L</searchLink>; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124, Bari, Italy.<br /><searchLink fieldCode="AU" term="%22Azzariti+A%22">Azzariti A</searchLink>; Laboratory of Experimental Pharmacology, IRCCS Istituto Tumori Giovanni Paolo II, Viale Orazio Flacco, 65, 70124, Bari, Italy. a.azzariti@oncologico.bari.it.
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