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Surgery alone achieves comparable survival to adjuvant therapy in T4aN0M0 gingival squamous cell carcinoma with clear surgical margins: A registry-based propensity-matched analysis.

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Title: Surgery alone achieves comparable survival to adjuvant therapy in T4aN0M0 gingival squamous cell carcinoma with clear surgical margins: A registry-based propensity-matched analysis.
Authors: Tsai YT; Department of Otorhinolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan, ROC., Wen YW; Clinical Informatics and Medical Statistics Research Center, Chang Gung University, Taoyuan, Taiwan, ROC; Division of Thoracic Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC., Kang CJ; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC., Lin CY; Department of Radiation Oncology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC., Ng SH; Department of Diagnostic Radiology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC., Ch'ang HJ; National Institute of Cancer Research, National Health Research Institutes, Miaoli, Taiwan, ROC., Lou PJ; Department of Otolaryngology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan, ROC., Wang CP; Department of Otolaryngology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan, ROC., Lin JC; Department of Radiation Oncology, Changhua Christian Hospital, Changhua, Taiwan, ROC., Hua CH; Department of Otorhinolaryngology, China Medical University Hospital, Taichung, Taiwan, ROC., Lee SR; Research Service Center for Health Information, Chang Gung University, Taoyuan, Taiwan, ROC., Fan KH; Department of Radiation Oncology, New Taipei Municipal TuCheng Hospital, Taiwan, ROC., Chen WC; Department of Radiation Oncology, Chang Gung Memorial Hospital, Chiayi and Chang Gung University, Taoyuan, Taiwan, ROC., Lee LY; Department of Pathology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC., Chien CY; Kaohsiung Chang Gung Memorial Hospital, Doctoral Program of Clinical and Experimental Medicine, National Sun Yat-sen University, Taiwan, ROC., Chen TM; Department of Otolaryngology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan, ROC., Terng SD; Department of Head and Neck Surgery, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan, ROC., Tsai CY; Department of Oral and Maxillofacial Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, ROC., Wang HM; Department of Medical Oncology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC., Hsieh CH; Department of Medical Oncology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC., Yeh CH; Department of Radiation Oncology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC., Lin CH; Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC., Tsao CK; Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC., Cheng NM; Department of Nuclear Medicine and Molecular Imaging Center, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC., Fang TJ; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC., Huang SF; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC., Lee LA; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC., Fang KH; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC., Wang YC; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC., Lin WN; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC., Hsin LJ; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC., Yen TC; Department of Nuclear Medicine and Molecular Imaging Center, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC., Liao CT; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC. Electronic address: liaoct@cgmh.org.tw.
Source: Oral oncology [Oral Oncol] 2026 May; Vol. 176, pp. 107915. Date of Electronic Publication: 2026 Mar 03.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9709118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0593 (Electronic) Linking ISSN: 13688375 NLM ISO Abbreviation: Oral Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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An: 41780292
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PubType: Academic Journal
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  Label: Title
  Group: Ti
  Data: Surgery alone achieves comparable survival to adjuvant therapy in T4aN0M0 gingival squamous cell carcinoma with clear surgical margins: A registry-based propensity-matched analysis.
– Name: Author
  Label: Authors
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  Data: <searchLink fieldCode="AU" term="%22Tsai+YT%22">Tsai YT</searchLink>; Department of Otorhinolaryngology-Head and Neck Surgery, Chang Gung Memorial Hospital, Chiayi, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Wen+YW%22">Wen YW</searchLink>; Clinical Informatics and Medical Statistics Research Center, Chang Gung University, Taoyuan, Taiwan, ROC; Division of Thoracic Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Kang+CJ%22">Kang CJ</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lin+CY%22">Lin CY</searchLink>; Department of Radiation Oncology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Ng+SH%22">Ng SH</searchLink>; Department of Diagnostic Radiology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Ch'ang+HJ%22">Ch'ang HJ</searchLink>; National Institute of Cancer Research, National Health Research Institutes, Miaoli, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lou+PJ%22">Lou PJ</searchLink>; Department of Otolaryngology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Wang+CP%22">Wang CP</searchLink>; Department of Otolaryngology, National Taiwan University Hospital and College of Medicine, National Taiwan University, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lin+JC%22">Lin JC</searchLink>; Department of Radiation Oncology, Changhua Christian Hospital, Changhua, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Hua+CH%22">Hua CH</searchLink>; Department of Otorhinolaryngology, China Medical University Hospital, Taichung, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lee+SR%22">Lee SR</searchLink>; Research Service Center for Health Information, Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Fan+KH%22">Fan KH</searchLink>; Department of Radiation Oncology, New Taipei Municipal TuCheng Hospital, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chen+WC%22">Chen WC</searchLink>; Department of Radiation Oncology, Chang Gung Memorial Hospital, Chiayi and Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lee+LY%22">Lee LY</searchLink>; Department of Pathology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chien+CY%22">Chien CY</searchLink>; Kaohsiung Chang Gung Memorial Hospital, Doctoral Program of Clinical and Experimental Medicine, National Sun Yat-sen University, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Chen+TM%22">Chen TM</searchLink>; Department of Otolaryngology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Terng+SD%22">Terng SD</searchLink>; Department of Head and Neck Surgery, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Tsai+CY%22">Tsai CY</searchLink>; Department of Oral and Maxillofacial Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Wang+HM%22">Wang HM</searchLink>; Department of Medical Oncology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Hsieh+CH%22">Hsieh CH</searchLink>; Department of Medical Oncology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Yeh+CH%22">Yeh CH</searchLink>; Department of Radiation Oncology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lin+CH%22">Lin CH</searchLink>; Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Tsao+CK%22">Tsao CK</searchLink>; Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Cheng+NM%22">Cheng NM</searchLink>; Department of Nuclear Medicine and Molecular Imaging Center, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Fang+TJ%22">Fang TJ</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Huang+SF%22">Huang SF</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lee+LA%22">Lee LA</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Fang+KH%22">Fang KH</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Wang+YC%22">Wang YC</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Lin+WN%22">Lin WN</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Hsin+LJ%22">Hsin LJ</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Yen+TC%22">Yen TC</searchLink>; Department of Nuclear Medicine and Molecular Imaging Center, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Liao+CT%22">Liao CT</searchLink>; Department of Otorhinolaryngology, Head and Neck Surgery, Linkou Chang Gung Memorial Hospital and Chang Gung University, at Linkou, No. 5, Fu-Hsing St., Kwei-Shan, Taoyuan, Taiwan, ROC. Electronic address: liaoct@cgmh.org.tw.
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  Data: <searchLink fieldCode="JN" term="%229709118%22">Oral oncology</searchLink> [Oral Oncol] 2026 May; Vol. 176, pp. 107915. <i>Date of Electronic Publication: </i>2026 Mar 03.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9709118 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0593 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213688375%22">13688375 </searchLink><i>NLM ISO Abbreviation: </i>Oral Oncol <i>Subsets: </i>MEDLINE
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