Genome-wide analyses of Mycobacterium tuberculosis complex isolates reveal insights into circulating lineages and drug resistance mutations in The Gambia.

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Title: Genome-wide analyses of Mycobacterium tuberculosis complex isolates reveal insights into circulating lineages and drug resistance mutations in The Gambia.
Authors: Faal F; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK., Top N; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia., Jobe O; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia., Colley SM; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia., Ayorinde A; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia., Mendy A; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia., Sarr-Kuyateh B; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia., Donkor S; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia., Antonio M; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK., de Jong BC; Institute of Tropical Medicine, Antwerp, Belgium., Rachow A; Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; German Center for Infection Research, Partner site Munich, Munich, Germany.; Unit Global Health, Helmholtz Zentrum München, German Research Centre for Environmental Health (HMGU), Neuherberg, Germany., Kampmann B; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.; Charité - Universitätsmedizin Berlin, Berlin, Germany., Sutherland JS; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK., Li H; VPD Heart and Lung Research Institute, University of Cambridge, Cambridge, UK., Blundell TL; VPD Heart and Lung Research Institute, University of Cambridge, Cambridge, UK., Campino S; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK., Kohl T; Molecular and Experimental Mycobacteriology, Research Center Borstel, Parkallee 1, 23845, Borstel, Germany., Dreyer V; Molecular and Experimental Mycobacteriology, Research Center Borstel, Parkallee 1, 23845, Borstel, Germany., Neimann S; Molecular and Experimental Mycobacteriology, Research Center Borstel, Parkallee 1, 23845, Borstel, Germany., Pandurangan AP; VPD Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; Gonville and Caius College, University of Cambridge, Cambridge, UK., Clark TG; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK., Phelan JE; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK., Tientcheu LD; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia. leopold.tientcheu@lshtm.ac.uk.; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK. leopold.tientcheu@lshtm.ac.uk.; Department of Biochemistry, Faculty of Sciences, University of Yaoundé 1, Yaoundé, Cameroon. leopold.tientcheu@lshtm.ac.uk.
Source: Scientific reports [Sci Rep] 2026 Mar 04; Vol. 16 (1). Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
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  Data: Genome-wide analyses of Mycobacterium tuberculosis complex isolates reveal insights into circulating lineages and drug resistance mutations in The Gambia.
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  Data: <searchLink fieldCode="AU" term="%22Faal+F%22">Faal F</searchLink>; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Top+N%22">Top N</searchLink>; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.<br /><searchLink fieldCode="AU" term="%22Jobe+O%22">Jobe O</searchLink>; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.<br /><searchLink fieldCode="AU" term="%22Colley+SM%22">Colley SM</searchLink>; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.<br /><searchLink fieldCode="AU" term="%22Ayorinde+A%22">Ayorinde A</searchLink>; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.<br /><searchLink fieldCode="AU" term="%22Mendy+A%22">Mendy A</searchLink>; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.<br /><searchLink fieldCode="AU" term="%22Sarr-Kuyateh+B%22">Sarr-Kuyateh B</searchLink>; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.<br /><searchLink fieldCode="AU" term="%22Donkor+S%22">Donkor S</searchLink>; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.<br /><searchLink fieldCode="AU" term="%22Antonio+M%22">Antonio M</searchLink>; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22de+Jong+BC%22">de Jong BC</searchLink>; Institute of Tropical Medicine, Antwerp, Belgium.<br /><searchLink fieldCode="AU" term="%22Rachow+A%22">Rachow A</searchLink>; Institute of Infectious Diseases and Tropical Medicine, LMU University Hospital, LMU Munich, Munich, Germany.; German Center for Infection Research, Partner site Munich, Munich, Germany.; Unit Global Health, Helmholtz Zentrum München, German Research Centre for Environmental Health (HMGU), Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kampmann+B%22">Kampmann B</searchLink>; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.; Charité - Universitätsmedizin Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Sutherland+JS%22">Sutherland JS</searchLink>; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia.; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; VPD Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Blundell+TL%22">Blundell TL</searchLink>; VPD Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Campino+S%22">Campino S</searchLink>; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Kohl+T%22">Kohl T</searchLink>; Molecular and Experimental Mycobacteriology, Research Center Borstel, Parkallee 1, 23845, Borstel, Germany.<br /><searchLink fieldCode="AU" term="%22Dreyer+V%22">Dreyer V</searchLink>; Molecular and Experimental Mycobacteriology, Research Center Borstel, Parkallee 1, 23845, Borstel, Germany.<br /><searchLink fieldCode="AU" term="%22Neimann+S%22">Neimann S</searchLink>; Molecular and Experimental Mycobacteriology, Research Center Borstel, Parkallee 1, 23845, Borstel, Germany.<br /><searchLink fieldCode="AU" term="%22Pandurangan+AP%22">Pandurangan AP</searchLink>; VPD Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; Gonville and Caius College, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Clark+TG%22">Clark TG</searchLink>; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Phelan+JE%22">Phelan JE</searchLink>; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK.<br /><searchLink fieldCode="AU" term="%22Tientcheu+LD%22">Tientcheu LD</searchLink>; MRC Unit The Gambia at London School of Hygiene and Tropical Medicine, Banjul, The Gambia. leopold.tientcheu@lshtm.ac.uk.; Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK. leopold.tientcheu@lshtm.ac.uk.; Department of Biochemistry, Faculty of Sciences, University of Yaoundé 1, Yaoundé, Cameroon. leopold.tientcheu@lshtm.ac.uk.
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