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Oxidized PDI promotes thrombus formation in oxidative stress.

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Title: Oxidized PDI promotes thrombus formation in oxidative stress.
Authors: Yang M; Bloodworks Northwest Research Institute, Seattle, WA.; Division of Hematology and Oncology, Department of Medicine, University of Washington School of Medicine, Seattle, WA.; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA., Owegie OC; Bloodworks Northwest Research Institute, Seattle, WA., Patel A; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA., Kennedy QP; Bloodworks Northwest Research Institute, Seattle, WA.; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA., Flaumenhaft JT; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA., Chinnaraj M; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO., Ponzar N; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO., Fulcidor EM; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA., Rico MC; Department of Cardiovascular Sciences, Sol Sherry Thrombosis Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA., Bhowmik A; Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL., Carroll KS; Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL., Handy DE; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Loscalzo J; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA., Essex DW; Department of Cardiovascular Sciences, Sol Sherry Thrombosis Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA., Pozzi N; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO., Flaumenhaft R; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.
Source: Blood [Blood] 2026 Jul 16; Vol. 148 (3), pp. 376-388.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
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  Data: Oxidized PDI promotes thrombus formation in oxidative stress.
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  Data: <searchLink fieldCode="AU" term="%22Yang+M%22">Yang M</searchLink>; Bloodworks Northwest Research Institute, Seattle, WA.; Division of Hematology and Oncology, Department of Medicine, University of Washington School of Medicine, Seattle, WA.; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Owegie+OC%22">Owegie OC</searchLink>; Bloodworks Northwest Research Institute, Seattle, WA.<br /><searchLink fieldCode="AU" term="%22Patel+A%22">Patel A</searchLink>; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Kennedy+QP%22">Kennedy QP</searchLink>; Bloodworks Northwest Research Institute, Seattle, WA.; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Flaumenhaft+JT%22">Flaumenhaft JT</searchLink>; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Chinnaraj+M%22">Chinnaraj M</searchLink>; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO.<br /><searchLink fieldCode="AU" term="%22Ponzar+N%22">Ponzar N</searchLink>; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO.<br /><searchLink fieldCode="AU" term="%22Fulcidor+EM%22">Fulcidor EM</searchLink>; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Rico+MC%22">Rico MC</searchLink>; Department of Cardiovascular Sciences, Sol Sherry Thrombosis Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Bhowmik+A%22">Bhowmik A</searchLink>; Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL.<br /><searchLink fieldCode="AU" term="%22Carroll+KS%22">Carroll KS</searchLink>; Department of Chemistry and Biochemistry, Florida Atlantic University, Boca Raton, FL.<br /><searchLink fieldCode="AU" term="%22Handy+DE%22">Handy DE</searchLink>; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Loscalzo+J%22">Loscalzo J</searchLink>; Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Essex+DW%22">Essex DW</searchLink>; Department of Cardiovascular Sciences, Sol Sherry Thrombosis Research Center, Lewis Katz School of Medicine, Temple University, Philadelphia, PA.<br /><searchLink fieldCode="AU" term="%22Pozzi+N%22">Pozzi N</searchLink>; Edward A. Doisy Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, St. Louis, MO.<br /><searchLink fieldCode="AU" term="%22Flaumenhaft+R%22">Flaumenhaft R</searchLink>; Division of Hemostasis and Thrombosis, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA.
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        Value: 10.1182/blood.2025031756
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              Text: 2026 Jul 16
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