Prospective study of patients with immune checkpoint inhibitor-induced hepatitis; characterization of liver injury, outcome of therapy, and management of steroid-unresponsive and steroid-dependent hepatitis.
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| Title: | Prospective study of patients with immune checkpoint inhibitor-induced hepatitis; characterization of liver injury, outcome of therapy, and management of steroid-unresponsive and steroid-dependent hepatitis. |
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| Authors: | Holmstroem RB; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark., Teisner AS; Department of Medical Gastroenterology and Hepatology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark., Sweep MWD; Department of Medical Oncology, Radboud University Medical Center, Nijmegen, Netherlands.; Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, Netherlands., Noringriis IM; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark., Khan S; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark., Aagaard NK; Department of Medical Gastroenterology and Hepatology, Aarhus University Hospital, Aarhus, Denmark., Karlström J; Division of Oncology, Department of Clinical Science, Faculty of Medicine, Lund University, Lund, Sweden., Jurlander RS; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark., Sohlin JE; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark., Monberg TJ; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark., Vestergaard C; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark., Stoltenborg Granhøj J; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark., Stenbøg P; Department of Medical Gastroenterology and Hepatology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark., Toxvaerd A; Department of Pathology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark., Hansen AB; Department of Pathology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark., Bjerring PN; Department of Transplantation and Digestive Diseases, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Capital Region of Denmark, Denmark., Lorentzen T; Department of Medical Gastroenterology and Hepatology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.; Department of Radiology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark., Thielsen P; Department of Medical Gastroenterology and Hepatology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.; Department of Radiology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark., Bol K; Department of Medical Oncology, Radboud University Medical Center, Nijmegen, Netherlands.; Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, Netherlands., Jonsson G; Division of Oncology, Department of Clinical Science, Faculty of Medicine, Lund University, Lund, Sweden., Ellebaek E; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark., Svane IM; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark Inge.Marie.Svane@regionh.dk. |
| Source: | Journal for immunotherapy of cancer [J Immunother Cancer] 2026 Mar 05; Vol. 14 (3). Date of Electronic Publication: 2026 Mar 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41786454 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Prospective study of patients with immune checkpoint inhibitor-induced hepatitis; characterization of liver injury, outcome of therapy, and management of steroid-unresponsive and steroid-dependent hepatitis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Holmstroem+RB%22">Holmstroem RB</searchLink>; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Teisner+AS%22">Teisner AS</searchLink>; Department of Medical Gastroenterology and Hepatology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Sweep+MWD%22">Sweep MWD</searchLink>; Department of Medical Oncology, Radboud University Medical Center, Nijmegen, Netherlands.; Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, Netherlands.<br /><searchLink fieldCode="AU" term="%22Noringriis+IM%22">Noringriis IM</searchLink>; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Khan+S%22">Khan S</searchLink>; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Aagaard+NK%22">Aagaard NK</searchLink>; Department of Medical Gastroenterology and Hepatology, Aarhus University Hospital, Aarhus, Denmark.<br /><searchLink fieldCode="AU" term="%22Karlström+J%22">Karlström J</searchLink>; Division of Oncology, Department of Clinical Science, Faculty of Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Jurlander+RS%22">Jurlander RS</searchLink>; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Sohlin+JE%22">Sohlin JE</searchLink>; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Monberg+TJ%22">Monberg TJ</searchLink>; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Vestergaard+C%22">Vestergaard C</searchLink>; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Stoltenborg+Granhøj+J%22">Stoltenborg Granhøj J</searchLink>; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Stenbøg+P%22">Stenbøg P</searchLink>; Department of Medical Gastroenterology and Hepatology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Toxvaerd+A%22">Toxvaerd A</searchLink>; Department of Pathology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Hansen+AB%22">Hansen AB</searchLink>; Department of Pathology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Bjerring+PN%22">Bjerring PN</searchLink>; Department of Transplantation and Digestive Diseases, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Lorentzen+T%22">Lorentzen T</searchLink>; Department of Medical Gastroenterology and Hepatology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.; Department of Radiology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Thielsen+P%22">Thielsen P</searchLink>; Department of Medical Gastroenterology and Hepatology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.; Department of Radiology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Bol+K%22">Bol K</searchLink>; Department of Medical Oncology, Radboud University Medical Center, Nijmegen, Netherlands.; Department of Medical BioSciences, Radboud University Medical Center, Nijmegen, Netherlands.<br /><searchLink fieldCode="AU" term="%22Jonsson+G%22">Jonsson G</searchLink>; Division of Oncology, Department of Clinical Science, Faculty of Medicine, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Ellebaek+E%22">Ellebaek E</searchLink>; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark.<br /><searchLink fieldCode="AU" term="%22Svane+IM%22">Svane IM</searchLink>; National Center for Cancer Immune Therapy (CCIT-DK), Department of Oncology, Copenhagen University Hospital - Herlev and Gentofte Hospital, Herlev, Capital Region of Denmark, Denmark Inge.Marie.Svane@regionh.dk. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101620585%22">Journal for immunotherapy of cancer</searchLink> [J Immunother Cancer] 2026 Mar 05; Vol. 14 (3). <i>Date of Electronic Publication: </i>2026 Mar 05. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BMJ+Publishing+Group+Ltd%22">BMJ Publishing Group Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101620585 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2051-1426 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220511426%22">20511426 </searchLink><i>NLM ISO Abbreviation: </i>J Immunother Cancer <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41786454 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1136/jitc-2025-013861 Languages: – Code: eng Text: English Titles: – TitleFull: Prospective study of patients with immune checkpoint inhibitor-induced hepatitis; characterization of liver injury, outcome of therapy, and management of steroid-unresponsive and steroid-dependent hepatitis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Holmstroem RB – PersonEntity: Name: NameFull: Teisner AS – PersonEntity: Name: NameFull: Sweep MWD – PersonEntity: Name: NameFull: Noringriis IM – PersonEntity: Name: NameFull: Khan S – PersonEntity: Name: NameFull: Aagaard NK – PersonEntity: Name: NameFull: Karlström J – PersonEntity: Name: NameFull: Jurlander RS – PersonEntity: Name: NameFull: Sohlin JE – PersonEntity: Name: NameFull: Monberg TJ – PersonEntity: Name: NameFull: Vestergaard C – PersonEntity: Name: NameFull: Stoltenborg Granhøj J – PersonEntity: Name: NameFull: Stenbøg P – PersonEntity: Name: NameFull: Toxvaerd A – PersonEntity: Name: NameFull: Hansen AB – PersonEntity: Name: NameFull: Bjerring PN – PersonEntity: Name: NameFull: Lorentzen T – PersonEntity: Name: NameFull: Thielsen P – PersonEntity: Name: NameFull: Bol K – PersonEntity: Name: NameFull: Jonsson G – PersonEntity: Name: NameFull: Ellebaek E – PersonEntity: Name: NameFull: Svane IM IsPartOfRelationships: – BibEntity: Dates: – D: 05 M: 03 Text: 2026 Mar 05 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2051-1426 Numbering: – Type: volume Value: 14 – Type: issue Value: 3 Titles: – TitleFull: Journal for immunotherapy of cancer Type: main |
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