Glycoengineering CAR-T cells to overcome galectin-3-mediated immunosuppression.

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Title: Glycoengineering CAR-T cells to overcome galectin-3-mediated immunosuppression.
Authors: Lau LS; Department of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, United States., Suarez M; Department of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, United States., Fernandez B; Department of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, United States., Souchak J; Department of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, United States., Antonopoulos A; Department of Life Sciences, Imperial College London, London, United Kingdom.; Department of Wine, Vine & Beverage Sciences, School of Food Sciences, University of West Attica, Athens, Greece., Hu N; Department of Biostatistics, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL, United States., Abreu MM; Miami Cancer Institute, Baptist Health-South Florida, Miami, FL, United States., Koehne G; Miami Cancer Institute, Baptist Health-South Florida, Miami, FL, United States., Dell A; Department of Life Sciences, Imperial College London, London, United Kingdom., Haslam SM; Department of Life Sciences, Imperial College London, London, United Kingdom., Posey AD Jr; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, United States., Dimitroff CJ; Department of Cellular and Molecular Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL, United States.
Source: Frontiers in immunology [Front Immunol] 2026 Feb 18; Vol. 17, pp. 1766555. Date of Electronic Publication: 2026 Feb 18 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1766555