Computational Design, Synthesis, and Evaluation of Stapled Peptide-Based Antagonists of the CGRP Receptor.

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Bibliographic Details
Title: Computational Design, Synthesis, and Evaluation of Stapled Peptide-Based Antagonists of the CGRP Receptor.
Authors: Schofield AL; EaStChem School of Chemistry, The University of Edinburgh, Joseph Black Building, David Brewster Road, Edinburgh EH9 3FJ, U.K., Notari E; EaStChem School of Chemistry, The University of Edinburgh, Joseph Black Building, David Brewster Road, Edinburgh EH9 3FJ, U.K., Rožňovcová M; School of Pharmacy, University of Reading, Reading RG6 6AP, U.K., Cox KW; School of Pharmacy, University of Reading, Reading RG6 6AP, U.K., D'Aloisio V; School of Pharmacy and Biomolecular Sciences, Faculty of Science, Liverpool John Moores University, Liverpool L3 3AF, U.K., Steuer C; Institute of Pharmaceutical Sciences, ETH Zurich, HCI H401, Vladimir-Prelog-Weg 1-5/10, Zurich 8093, Switzerland., Michel J; EaStChem School of Chemistry, The University of Edinburgh, Joseph Black Building, David Brewster Road, Edinburgh EH9 3FJ, U.K., Cottrell GS; School of Pharmacy, University of Reading, Reading RG6 6AP, U.K., Coxon CR; EaStChem School of Chemistry, The University of Edinburgh, Joseph Black Building, David Brewster Road, Edinburgh EH9 3FJ, U.K.
Source: Journal of medicinal chemistry [J Med Chem] 2026 Mar 26; Vol. 69 (6), pp. 7142-7159. Date of Electronic Publication: 2026 Mar 06.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1520-4804
DOI:10.1021/acs.jmedchem.5c03445