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The fibrinogen αC region promotes arterial thrombosis in the context of hypofibrinogenemia.

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Title: The fibrinogen αC region promotes arterial thrombosis in the context of hypofibrinogenemia.
Authors: Lee RH; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Ferraresso F; Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.; Versiti Blood Research Institute, Milwaukee, WI., Couzens A; Department of Genetic Medicine and Development, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Jameson AT; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Department of Pathology and Laboratory Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Hanes HE; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Department of Pathology and Laboratory Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Casini A; Division of Angiology and Hemostasis, University Hospitals of Geneva, Geneva, Switzerland., Neerman-Arbez M; Department of Genetic Medicine and Development, Faculty of Medicine, University of Geneva, Geneva, Switzerland., Nieswandt B; Institute of Experimental Biomedicine I, Würzburg, Germany., Kastrup CJ; Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.; Versiti Blood Research Institute, Milwaukee, WI.; Department of Surgery, Medical College of Wisconsin, Milwaukee, WI.; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI.; Department of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI.; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI., Bergmeier W; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Flick MJ; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Department of Pathology and Laboratory Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC., Hur WS; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Department of Pathology and Laboratory Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Source: Blood [Blood] 2026 Jun 04; Vol. 147 (23), pp. 2821-2827.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
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  Data: The fibrinogen αC region promotes arterial thrombosis in the context of hypofibrinogenemia.
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  Data: <searchLink fieldCode="AU" term="%22Lee+RH%22">Lee RH</searchLink>; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Ferraresso+F%22">Ferraresso F</searchLink>; Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.; Versiti Blood Research Institute, Milwaukee, WI.<br /><searchLink fieldCode="AU" term="%22Couzens+A%22">Couzens A</searchLink>; Department of Genetic Medicine and Development, Faculty of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Jameson+AT%22">Jameson AT</searchLink>; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Department of Pathology and Laboratory Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Hanes+HE%22">Hanes HE</searchLink>; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Department of Pathology and Laboratory Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Casini+A%22">Casini A</searchLink>; Division of Angiology and Hemostasis, University Hospitals of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Neerman-Arbez+M%22">Neerman-Arbez M</searchLink>; Department of Genetic Medicine and Development, Faculty of Medicine, University of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Nieswandt+B%22">Nieswandt B</searchLink>; Institute of Experimental Biomedicine I, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Kastrup+CJ%22">Kastrup CJ</searchLink>; Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, BC, Canada.; Versiti Blood Research Institute, Milwaukee, WI.; Department of Surgery, Medical College of Wisconsin, Milwaukee, WI.; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, WI.; Department of Biomedical Engineering, Medical College of Wisconsin, Milwaukee, WI.; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, WI.<br /><searchLink fieldCode="AU" term="%22Bergmeier+W%22">Bergmeier W</searchLink>; Department of Biochemistry and Biophysics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Flick+MJ%22">Flick MJ</searchLink>; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Department of Pathology and Laboratory Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.<br /><searchLink fieldCode="AU" term="%22Hur+WS%22">Hur WS</searchLink>; UNC Blood Research Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Department of Pathology and Laboratory Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.; Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
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              Text: 2026 Jun 04
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